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PDB: 10 件
8C7M
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BU of 8c7m by Molmil
Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb fragment.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FAb4 Crystal Kappa Light chain, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-01-16
公開日2024-01-31
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8CR5
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BU of 8cr5 by Molmil
Murine Interleukin-12 receptor beta 1 domain 1 in complex with murine Interleukin-12 beta.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, Interleukin-12 subunit beta, ...
著者Merceron, R, Bloch, Y, Felix, J, Savvides, S.N.
登録日2023-03-07
公開日2024-02-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8CR6
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BU of 8cr6 by Molmil
mouse Interleukin-12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 subunit alpha, Interleukin-12 subunit beta, ...
著者Merceron, R, Felix, J, Lambert, E, Bloch, Y, Savvides, S.N.
登録日2023-03-07
公開日2024-02-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8ODZ
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BU of 8odz by Molmil
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ...
著者Felix, J, Bloch, Y, Savvides, S.N.
登録日2023-03-10
公開日2024-02-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8OE4
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BU of 8oe4 by Molmil
Cryo-EM structure of a pre-dimerized human IL-23 complete extracellular signaling complex.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ...
著者Bloch, Y, Felix, J, Savvides, S.N.
登録日2023-03-10
公開日2024-02-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8OE0
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BU of 8oe0 by Molmil
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 2).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ...
著者Felix, J, Bloch, Y, Savvides, S.N.
登録日2023-03-10
公開日2024-02-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8ODX
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BU of 8odx by Molmil
Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb4 fragment and VHH.
分子名称: FAb4 Heavy chain, FAb4 Light chain, Interleukin-12 receptor subunit beta-1, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-03-09
公開日2024-02-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8PPM
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BU of 8ppm by Molmil
IL-12Rb1 neutralizing Fab4, crystal kappa variant
分子名称: Fab4 Light chain, crystal kappa variant, Fab4 heavy chain, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-07-07
公開日2024-02-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8PB1
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BU of 8pb1 by Molmil
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1), obtained after local refinement.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ...
著者Felix, J, Bloch, Y, Savvides, S.N.
登録日2023-06-08
公開日2024-02-07
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8CR8
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BU of 8cr8 by Molmil
human Interleukin-23
分子名称: Interleukin-12 subunit beta, Interleukin-23 subunit alpha, TERBIUM(III) ION, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-03-08
公開日2024-02-07
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024

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件を2024-11-06に公開中

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