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PDB: 223166 件

1KV0
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Cis/trans Isomerization of Non-prolyl Peptide Bond Observed in Crystal Structure of an Scorpion Toxin
分子名称: Alpha-like toxin BmK-M7
著者Guan, R.J, He, X.L, Wang, M, Xiang, Y, Wang, D.C.
登録日2002-01-23
公開日2003-09-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins.
J.Mol.Biol., 341, 2004
1KV1
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p38 MAP Kinase in Complex with Inhibitor 1
分子名称: 1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA, p38 MAP kinase
著者Pargellis, C, Tong, L, Churchill, L, Cirillo, P.F, Gilmore, T, Graham, A.G, Grob, P.M, Hickey, E.R, Moss, N, Pav, S, Regan, J.
登録日2002-01-23
公開日2002-03-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site.
Nat.Struct.Biol., 9, 2002
1KV2
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Human p38 MAP Kinase in Complex with BIRB 796
分子名称: 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, p38 MAP kinase
著者Pargellis, C, Tong, L, Churchill, L, Cirillo, P.F, Gilmore, T, Graham, A.G, Grob, P.M, Hickey, E.R, Moss, N, Pav, S, Regan, J.
登録日2002-01-23
公開日2002-03-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site.
Nat.Struct.Biol., 9, 2002
1KV3
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HUMAN TISSUE TRANSGLUTAMINASE IN GDP BOUND FORM
分子名称: GUANOSINE-5'-DIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase
著者Liu, S, Cerione, R.A, Clardy, J.
登録日2002-01-24
公開日2002-03-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KV4
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Solution structure of antibacterial peptide (Moricin)
分子名称: moricin
著者Hemmi, H, Ishibashi, J, Hara, S, Yamakawa, M.
登録日2002-01-25
公開日2002-05-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of moricin, an antibacterial peptide, isolated from the silkworm Bombyx mori.
FEBS Lett., 518, 2002
1KV5
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Structure of Trypanosoma brucei brucei TIM with the salt-bridge-forming residue Arg191 mutated to Ser
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, ...
著者Kursula, I, Partanen, S, Lambeir, A.-M, Wierenga, R.K.
登録日2002-01-25
公開日2002-03-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The importance of the conserved Arg191-Asp227 salt bridge of triosephosphate isomerase for folding, stability, and catalysis
FEBS Lett., 518, 2002
1KV6
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X-ray structure of the orphan nuclear receptor ERR3 ligand-binding domain in the constitutively active conformation
分子名称: ESTROGEN-RELATED RECEPTOR GAMMA, steroid receptor coactivator 1
著者Greschik, H, Wurtz, J.-M, Sanglier, S, Bourguet, W, van Dorsselaer, A, Moras, D, Renaud, J.-P, Structural Proteomics in Europe (SPINE)
登録日2002-01-25
公開日2003-01-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Functional Evidence for Ligand-Independent Transcriptional Activation by the Estrogen-Related Receptor 3
Mol.Cell, 9, 2002
1KV7
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Crystal Structure of CueO, a multi-copper oxidase from E. coli involved in copper homeostasis
分子名称: COPPER (II) ION, CU-O-CU LINKAGE, PROBABLE BLUE-COPPER PROTEIN YACK
著者Roberts, S.A, Weichsel, A, Grass, G, Thakali, K, Hazzard, J.T, Tollin, G, Rensing, C, Montfort, W.R.
登録日2002-01-25
公開日2002-02-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure and electron transfer kinetics of CueO, a multicopper oxidase required for copper homeostasis in Escherichia coli.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KV8
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Crystal Structure of 3-Keto-L-Gulonate 6-Phosphate Decarboxylase
分子名称: 3-Keto-L-Gulonate 6-Phosphate Decarboxylase, MAGNESIUM ION, PHOSPHATE ION
著者Wise, E, Yew, W.S, Babbitt, P.C, Gerlt, J.A, Rayment, I.
登録日2002-01-25
公開日2002-04-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Homologous (beta/alpha)8-barrel enzymes that catalyze unrelated reactions: orotidine 5'-monophosphate decarboxylase and 3-keto-L-gulonate 6-phosphate decarboxylase.
Biochemistry, 41, 2002
1KV9
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Structure at 1.9 A Resolution of a Quinohemoprotein Alcohol Dehydrogenase from Pseudomonas putida HK5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETONE, CALCIUM ION, ...
著者Chen, Z.-W, Matsushita, K, Yamashita, T, Fujii, T, Toyama, H, Adachi, O, Bellamy, H.D, Mathews, F.S.
登録日2002-01-25
公開日2002-07-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure at 1.9 A resolution of a quinohemoprotein alcohol dehydrogenase from Pseudomonas putida HK5.
Structure, 10, 2002
1KVA
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E. COLI RIBONUCLEASE HI D134A MUTANT
分子名称: RIBONUCLEASE H
著者Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
登録日1996-10-04
公開日1997-03-12
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1KVB
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E. COLI RIBONUCLEASE HI D134H MUTANT
分子名称: RIBONUCLEASE H
著者Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
登録日1996-10-04
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1KVC
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E. COLI RIBONUCLEASE HI D134N MUTANT
分子名称: RIBONUCLEASE H
著者Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
登録日1996-10-04
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1KVD
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KILLER TOXIN FROM HALOTOLERANT YEAST
分子名称: SMK TOXIN, SULFATE ION
著者Kashiwagi, T, Kunishima, N, Suzuki, C, Tsuchiya, F, Nikkuni, S, Arata, Y, Morikawa, K.
登録日1996-10-04
公開日1997-04-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The novel acidophilic structure of the killer toxin from halotolerant yeast demonstrates remarkable folding similarity with a fungal killer toxin.
Structure, 5, 1997
1KVE
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KILLER TOXIN FROM HALOTOLERANT YEAST
分子名称: SMK TOXIN
著者Kashiwagi, T, Kunishima, N, Suzuki, C, Tsuchiya, F, Nikkuni, S, Arata, Y, Morikawa, K.
登録日1996-10-04
公開日1997-04-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The novel acidophilic structure of the killer toxin from halotolerant yeast demonstrates remarkable folding similarity with a fungal killer toxin.
Structure, 5, 1997
1KVF
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EMP-18 Erythropoietin Receptor Agonist Peptide
分子名称: PROTEIN: EMP-18 Receptor Agonist
著者Skelton, N.J, Russell, S, de Sauvage, F, Cochran, A.G.
登録日2002-01-25
公開日2002-03-06
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Amino acid determinants of beta-hairpin conformation in erythropoeitin receptor agonist peptides derived from a phage display library
J.Mol.Biol., 316, 2002
1KVG
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EPO-3 beta Hairpin Peptide
分子名称: Protein: EPO-3 Receptor Agonist
著者Skelton, N.J, Russell, S, de Sauvage, F, Cochran, A.G.
登録日2002-01-25
公開日2002-03-06
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Amino Acid Determinants of beta-Hairpin Conformation in Erythropoeitin Receptor Agonist Peptides Derived from a Phage Display Library
J.Mol.Biol., 316, 2002
1KVH
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NCSi-gb-bulge-DNA complex induced formation of a DNA bulge structure by a molecular wedge ligand-post-activated neocarzinostatin chromophore
分子名称: 5'-D(*CP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*TP*TP*CP*GP*GP*G)-3', SPIRO[[7-METHOXY-5-METHYL-1,2-DIHYDRO-NAPHTHALENE]-3,1'-[5-HYDROXY-9-[2-METHYLAMINO-2,6-DIDEOXYGALACTOPYRANOSYL-OXY]-5-(2-OXO-[1,3]DIOXOLAN-4-YL)-3A,5,9,9A-TETRAHYDRO-3H-1-OXA-CYCLOPENTA[A]-S-INDACEN-2-ONE]]
著者Gao, X, Stassinopoulos, A, Ji, J, Kwon, Y, Bare, S, Goldberg, I.H.
登録日2002-01-26
公開日2002-06-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Induced formation of a DNA bulge structure by a molecular wedge ligand-postactivated neocarzinostatin chromophore.
Biochemistry, 41, 2002
1KVI
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Solution Structure of the Reduced Form of the First Heavy Metal Binding Motif of the Menkes Protein
分子名称: Copper-transporting ATPase 1
著者De Silva, T.M, Veglia, G, Opella, S.J.
登録日2002-01-26
公開日2003-11-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of the reduced and Cu(I) bound forms of the first metal binding sequence of ATP7A associated with Menkes disease.
Proteins, 61, 2005
1KVJ
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Solution Structure of the Cu(I) bound form of the first heavy metal binding motif of the Menkes protein
分子名称: COPPER (I) ION, Copper-transporting ATPase 1
著者De Silva, T.M, Veglia, G, Opella, S.J.
登録日2002-01-26
公開日2003-11-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of the reduced and Cu(I) bound forms of the first metal binding sequence of ATP7A associated with Menkes disease.
Proteins, 61, 2005
1KVK
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The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mevalonate kinase
著者Fu, Z, Wang, M, Potter, D, Mizioko, H.M, Kim, J.J.
登録日2002-01-26
公開日2002-03-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
1KVL
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X-ray Crystal Structure of AmpC S64G Mutant beta-Lactamase in Complex with Substrate and Product Forms of Cephalothin
分子名称: 2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, 2-[CARBOXY-(2-THIOPHEN-2-YL-ACETYLAMINO)-METHYL]-5-METHYLENE-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase, ...
著者Beadle, B.M, Trehan, I, Focia, P.J, Shoichet, B.K.
登録日2002-01-27
公開日2002-03-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural milestones in the reaction pathway of an amide hydrolase: substrate, acyl, and product complexes of cephalothin with AmpC beta-lactamase.
Structure, 10, 2002
1KVM
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X-ray Crystal Structure of AmpC WT beta-Lactamase in Complex with Covalently Bound Cephalothin
分子名称: 5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, PHOSPHATE ION, beta-lactamase
著者Beadle, B.M, Trehan, I, Focia, P.J, Shoichet, B.K.
登録日2002-01-27
公開日2002-03-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structural milestones in the reaction pathway of an amide hydrolase: substrate, acyl, and product complexes of cephalothin with AmpC beta-lactamase.
Structure, 10, 2002
1KVN
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Solution Structure Of Protein SRP19 Of The Arhaeoglobus fulgidus Signal Recognition Particle, 10 Structures
分子名称: SRP19
著者Pakhomova, O.N, Deep, S, Huang, Q, Zwieb, C, Hinck, A.P.
登録日2002-01-27
公開日2002-03-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of protein SRP19 of Archaeoglobus fulgidus signal recognition particle.
J.Mol.Biol., 317, 2002
1KVO
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HUMAN PHOSPHOLIPASE A2 COMPLEXED WITH A HIGHLY POTENT SUBSTRATE ANOLOGUE
分子名称: 4-(S)-[(1-OXO-7-PHENYLHEPTYL)AMINO]-5-[4-(PHENYLMETHYL)PHENYLTHIO]PENTANOIC ACID, CALCIUM ION, HUMAN PHOSPHOLIPASE A2
著者Cha, S.-S, Abdel-Meguid, S.S, Oh, B.-H.
登録日1996-07-29
公開日1997-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High-resolution X-ray crystallography reveals precise binding interactions between human nonpancreatic secreted phospholipase A2 and a highly potent inhibitor (FPL67047XX).
J.Med.Chem., 39, 1996

223166

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