Solution Structure of the Reduced Form of the First Heavy Metal Binding Motif of the Menkes Protein

Summary for 1KVI

DescriptorCopper-transporting ATPase 1 (1 entity in total)
Functional Keywordsmenkes, cu-protein, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationGolgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Isoform 3: Cytoplasm, cytosol (Probable). Isoform 5: Endoplasmic reticulum Q04656
Total number of polymer chains1
Total molecular weight8691.85
De Silva, T.M.,Veglia, G.,Opella, S.J. (deposition date: 2002-01-26, release date: 2003-11-18, Last modification date: 2011-07-13)
Primary citation
DeSilva, T.M.,Veglia, G.,Opella, S.J.
Solution structures of the reduced and Cu(I) bound forms of the first metal binding sequence of ATP7A associated with Menkes disease.
Proteins, 61:1038-1049, 2005
PubMed: 16211579 (PDB entries with the same primary citation)
DOI: 10.1002/prot.20639
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers787.5%28.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 1kvi
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