4RQX
| Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA | Descriptor: | 1-THIOETHANESULFONIC ACID, Peroxiredoxin-4 | Authors: | Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L. | Deposit date: | 2014-11-05 | Release date: | 2015-04-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.256 Å) | Cite: | Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787. Molecules, 20, 2015
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4FH8
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6UTL
| Yeast Thiol Specific antoxidant 2 with C171S mutation and catalytic cysteine alkylated with iodoacetamide | Descriptor: | Peroxiredoxin TSA2 | Authors: | Tairum, C.A, Bannitz-Fernandes, R, Tonoli, C.C.C, Murakami, M.T, de Oliveira, M.A, Netto, L.E.S. | Deposit date: | 2019-10-29 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Reduction of sulfenic acids by ascorbate in proteins, connecting thiol-dependent to alternative redox pathways. Free Radic Biol Med, 156, 2020
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3EMP
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7LJ1
| Human Prx1-Srx Decameric Complex | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Forshaw, T.E, Reisz, J.A, Nelson, K.J, Gumpena, R, Lawson, J.R, Jonsson, T, Wu, H, Clodfelter, J.E, Johnson, L, Furdui, C.M, Lowther, W.T. | Deposit date: | 2021-01-28 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State. Antioxidants (Basel), 10, 2021
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3HY2
| Crystal Structure of Sulfiredoxin in Complex with Peroxiredoxin I and ATP:Mg2+ | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxiredoxin-1, ... | Authors: | Jonsson, T.J, Johnson, L.C, Lowther, W.T. | Deposit date: | 2009-06-22 | Release date: | 2009-10-06 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Protein Engineering of the Quaternary Sulfiredoxin-Peroxiredoxin Enzyme-Substrate Complex Reveals the Molecular Basis for Cysteine Sulfinic Acid Phosphorylation J.Biol.Chem., 284, 2009
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5OVQ
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1E2Y
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5JCG
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5XBR
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5XBQ
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6P0W
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5JLY
| Structure of Peroxiredoxin-1 from Schistosoma japonicum | Descriptor: | Thioredoxin peroxidase-1 | Authors: | Wu, Q, Huang, F, Zeng, D, Liu, X, Zhao, J, Wang, H, Peng, Y, Li, P, Li, Y. | Deposit date: | 2016-04-27 | Release date: | 2017-05-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.051 Å) | Cite: | Crystal structure of Peroxiredoxin-1 from Schistosoma japonicum To Be Published
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6E0G
| Mitochondrial peroxiredoxin from Leishmania infantum after heat stress without unfolding client protein | Descriptor: | mitochondrial 2-cys-peroxiredoxin | Authors: | Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U. | Deposit date: | 2018-07-06 | Release date: | 2019-02-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun, 10, 2019
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6E0F
| Mitochondrial peroxiredoxin from Leishmania infantum in complex with unfolding client protein after heat stress | Descriptor: | mitochondrial 2-cys-peroxiredoxin | Authors: | Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U. | Deposit date: | 2018-07-06 | Release date: | 2019-02-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun, 10, 2019
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5HQP
| Crystal structure of the ERp44-peroxiredoxin 4 complex | Descriptor: | Endoplasmic reticulum resident protein 44, Peroxiredoxin-4 | Authors: | Yang, K, Li, D.F, Wang, X, Wang, C.C. | Deposit date: | 2016-01-22 | Release date: | 2016-10-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention. Structure, 24, 2016
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6Q5V
| 1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus | Descriptor: | Peroxiredoxin | Authors: | Stroobants, S, Maes, D, Peeters, E, van Molle, I. | Deposit date: | 2018-12-09 | Release date: | 2019-05-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.747 Å) | Cite: | Structure of the Prx6-subfamily 1-Cys peroxiredoxin from Sulfolobus islandicus. Acta Crystallogr.,Sect.F, 75, 2019
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5EPT
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7WEU
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7WET
| Crystal structure of Peroxiredoxin I in complex with the inhibitor Cela | Descriptor: | (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid, Peroxiredoxin-1 | Authors: | Zhang, H, Luo, C. | Deposit date: | 2021-12-24 | Release date: | 2022-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1. Signal Transduct Target Ther, 8, 2023
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8HH0
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8HLA
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8EKY
| Cryo-EM structure of the human PRDX4-ErP46 complex | Descriptor: | Peroxiredoxin-4, Thioredoxin domain-containing protein 5 | Authors: | Su, C.C. | Deposit date: | 2022-09-22 | Release date: | 2023-05-03 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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8EKW
| Cryo-EM structure of human PRDX4 | Descriptor: | Peroxiredoxin-4 | Authors: | Su, C.C. | Deposit date: | 2022-09-22 | Release date: | 2023-05-03 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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5DVB
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