4RQX

Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA

Summary for 4RQX

Entry DOI	10.2210/pdb4rqx/pdb
Descriptor	Peroxiredoxin-4, 1-THIOETHANESULFONIC ACID (3 entities in total)
Functional Keywords	peroxiredoxin, thioredoxin, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : Q13162
Total number of polymer chains	5
Total formula weight	127995.22
Authors	Badger, J.,Sridhar, V.,Logan, C.,Hausheer, F.H.,Nienaber, V.L. (deposition date: 2014-11-05, release date: 2015-04-01, Last modification date: 2023-09-20)
Primary citation	Parker, A.R.,Petluru, P.N.,Nienaber, V.L.,Badger, J.,Leverett, B.D.,Jair, K.,Sridhar, V.,Logan, C.,Ayala, P.Y.,Kochat, H.,Hausheer, F.H. Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787. Molecules, 20:4928-4950, 2015 Cited by PubMed: 25793542 DOI: 10.3390/molecules20034928 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.256 Å)

Structure validation