4RQX

Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0051920	molecular_function	peroxiredoxin activity
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0051920	molecular_function	peroxiredoxin activity
C	0016209	molecular_function	antioxidant activity
C	0016491	molecular_function	oxidoreductase activity
C	0051920	molecular_function	peroxiredoxin activity
D	0016209	molecular_function	antioxidant activity
D	0016491	molecular_function	oxidoreductase activity
D	0051920	molecular_function	peroxiredoxin activity
E	0016209	molecular_function	antioxidant activity
E	0016491	molecular_function	oxidoreductase activity
E	0051920	molecular_function	peroxiredoxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE COM A 301

Chain	Residue
A	CYS124
A	ARG164

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE COM B 301

Chain	Residue
B	VAL123
B	CYS124

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE COM C 301

Chain	Residue
C	CYS124

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE COM D 301

Chain	Residue
D	CYS124
D	ARG164

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE COM E 301

Chain	Residue
E	CYS124

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000305|PubMed:12059788, ECO:0000305|PubMed:21916849

Chain	Residue	Details
A	CYS124
B	CYS124
C	CYS124
D	CYS124
E	CYS124

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