4V2A
| human Unc5A ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NETRIN RECEPTOR UNC5A | Authors: | Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R. | Deposit date: | 2014-10-08 | Release date: | 2014-11-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development Neuron, 84, 2014
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7AHS
| titin-N2A Ig81-Ig83 | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Isoform 5 of Titin, ... | Authors: | Fleming, J.R, Mayans, O. | Deposit date: | 2020-09-25 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The N2A region of titin has a unique structural configuration. J.Gen.Physiol., 153, 2021
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5JDE
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7SJL
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2KKQ
| Solution NMR Structure of the Ig-like C2-type 2 Domain of Human Myotilin. Northeast Structural Genomics Target HR3158. | Descriptor: | Myotilin | Authors: | Rossi, P, Shastry, R, Ciccosanti, C, Hamilton, K, Xiao, R, Acton, T.B, Swapna, G.V.T, Nair, R, Everett, J.K, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-29 | Release date: | 2009-07-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of the Ig-like C2-type 2 Domain of Human Myotilin. Northeast Structural Genomics Target HR3158. To be Published
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8OVU
| Human titin immunoglobulin-like 21 domain | Descriptor: | MAGNESIUM ION, Titin | Authors: | Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M. | Deposit date: | 2023-04-26 | Release date: | 2023-11-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy. Cell Rep, 42, 2023
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8P35
| Mutant human titin immunoglobulin-like 21 domain - C3575S | Descriptor: | Titin | Authors: | Martinez-Martin, I, Crousilles, A, Mortensen, S.A, Alegre-Cebollada, J, Wilmanns, M. | Deposit date: | 2023-05-17 | Release date: | 2023-11-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy. Cell Rep, 42, 2023
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2KDG
| Solution Structure of the 1st Ig domain of Myotilin | Descriptor: | Myotilin | Authors: | Heikkinen, O, Kilpelainen, I, Permi, P, Koskela, H, Ylanne, J, Carpen, O. | Deposit date: | 2009-01-08 | Release date: | 2009-07-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the first immunoglobulin domain of human myotilin J.Biomol.Nmr, 44, 2009
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3GRW
| FGFR3 in complex with a Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | Authors: | Wiesmann, C. | Deposit date: | 2009-03-26 | Release date: | 2009-05-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J.Clin.Invest., 119, 2009
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3EUU
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6SDB
| Chimeric titin Z1Z2 functionalized with a KLER exogenous peptide from decorin | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ... | Authors: | Fleming, J.R, Hill, C, Mayans, O.M. | Deposit date: | 2019-07-26 | Release date: | 2019-09-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The ZT Biopolymer: A Self-Assembling Protein Scaffold for Stem Cell Applications. Int J Mol Sci, 20, 2019
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6J6Y
| FGFR4 D2 - Fab complex | Descriptor: | Fab Heavy chain, Fab light chain, Fibroblast growth factor receptor 4 | Authors: | Takahashi, M, Hanzawa, H. | Deposit date: | 2019-01-16 | Release date: | 2019-08-07 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity. Mol.Cancer Ther., 18, 2019
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6YJ0
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7LU6
| Crystal structure of the mouse Kirrel3 D1 homodimer | Descriptor: | Kin of IRRE-like protein 3, SODIUM ION | Authors: | Roman, C.A, Pak, J.S, Wang, J, Ozkan, E. | Deposit date: | 2021-02-21 | Release date: | 2021-11-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep, 37, 2021
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4UOW
| Crystal structure of the titin M10-Obscurin Ig domain 1 complex | Descriptor: | CHLORIDE ION, Obscurin, SODIUM ION, ... | Authors: | Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A. | Deposit date: | 2014-06-10 | Release date: | 2014-12-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The Crystal Structure of the Human Titin:Obscurin Complex Reveals a Conserved Yet Specific Muscle M-Band Zipper Module. J.Mol.Biol., 427, 2015
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7R67
| Human obscurin Ig13 | Descriptor: | Obscurin | Authors: | Moncure, G.E, Wright, N.T. | Deposit date: | 2021-06-22 | Release date: | 2022-11-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The N-terminus of obscurin is flexible in solution. Proteins, 91, 2023
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7R68
| Human obscurin Ig12 | Descriptor: | Obscurin | Authors: | Mauriello, G.E, Wright, N.T. | Deposit date: | 2021-06-22 | Release date: | 2022-11-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The N-terminus of obscurin is flexible in solution. Proteins, 91, 2023
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6MG9
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1NCU
| Titin Module M5, N-terminally Extended, NMR | Descriptor: | TITIN | Authors: | Pfuhl, M, Pastore, A. | Deposit date: | 1996-08-13 | Release date: | 1996-11-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | When a module is also a domain: the role of the N terminus in the stability and the dynamics of immunoglobulin domains from titin. J.Mol.Biol., 265, 1997
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1NCT
| TITIN MODULE M5, N-TERMINALLY EXTENDED, NMR | Descriptor: | TITIN | Authors: | Pfuhl, M, Pastore, A. | Deposit date: | 1996-08-13 | Release date: | 1996-11-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | When a module is also a domain: the role of the N terminus in the stability and the dynamics of immunoglobulin domains from titin. J.Mol.Biol., 265, 1997
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1PD6
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5MO9
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3CAF
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3KNB
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6FWX
| Chimeric titin Z1Z2-Z1Z2 tandem (Z1212) functionalized with a GRGDS exogenous peptide from fibronectin | Descriptor: | 1,2-ETHANEDIOL, Titin,Titin,Titin | Authors: | Mayans, O, Fleming, J, Hill, C. | Deposit date: | 2018-03-07 | Release date: | 2019-03-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Self-Assembling Proteins as High-Performance Substrates for Embryonic Stem Cell Self-Renewal. Adv. Mater. Weinheim, 31, 2019
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