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3GSL
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Crystal structure of PSD-95 tandem PDZ domains 1 and 2
Descriptor: Disks large homolog 4
Authors:Sainlos, M, Olivier, N.B, Imperiali, B.
Deposit date:2009-03-27
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization.
Nat.Chem.Biol., 7, 2011
4F8K
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BU of 4f8k by Molmil
Molecular analysis of the interaction between the prostacyclin receptor and the first PDZ domain of PDZK1
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Prostacyclin receptor
Authors:Kocher, O, Birrane, G, Kinsella, B.T, Mulvaney, E.P.
Deposit date:2012-05-17
Release date:2013-02-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Analysis of the Prostacyclin Receptor's Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1.
Plos One, 8, 2013
4UU5
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE
Descriptor: 2,2,4,4,6,6,8-heptamethylnonane, CHLORIDE ION, MAGUK P55 SUBFAMILY MEMBER 5, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2014-07-24
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
5VWK
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Crystal structure of human Scribble PDZ1:Beta-PIX complex
Descriptor: Beta-PIX, Protein scribble homolog, SULFATE ION
Authors:Lim, K.Y.B, Kvansakul, M.
Deposit date:2017-05-22
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX.
J. Biol. Chem., 292, 2017
7XTY
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Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide
Descriptor: APC-peptide, Tyrosine-protein phosphatase non-receptor type 13
Authors:Jing, L.Q, Sun, X.N, Ma, W.H, Zhou, W.J, Wu, D.L.
Deposit date:2022-05-18
Release date:2023-05-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer
to be published
4UU6
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
Deposit date:2014-07-24
Release date:2015-01-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
8OEP
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BU of 8oep by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide
Descriptor: Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3
Authors:Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C.
Deposit date:2023-03-11
Release date:2023-05-10
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity.
Front Mol Biosci, 10, 2023
4O06
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1.15A Resolution Structure of the Proteasome Assembly Chaperone Nas2 PDZ Domain
Descriptor: Probable 26S proteasome regulatory subunit p27, SULFATE ION, TETRAETHYLENE GLYCOL
Authors:Lovell, S, Mehzabeen, N, Battaile, K.P, Singh, C.R, Chowdhury, W.Q, Geanes, E, Roelofs, J.
Deposit date:2013-12-13
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:1.15 angstrom resolution structure of the proteasome-assembly chaperone Nas2 PDZ domain.
Acta Crystallogr F Struct Biol Commun, 70, 2014
1W9E
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Crystal structure of the PDZ tandem of human syntenin in complex with TNEFYF peptide
Descriptor: BENZOIC ACID, SYNTENIN 1, TNEFYF PEPTIDE
Authors:Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S.
Deposit date:2004-10-09
Release date:2006-03-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
1W9O
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Crystal structure of the PDZ tandem of human syntenin in complex with TNEYYV peptide
Descriptor: BENZOIC ACID, SYNTENIN 1, TNEYYV PEPTIDE
Authors:Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S.
Deposit date:2004-10-15
Release date:2006-03-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
2G5M
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BU of 2g5m by Molmil
Spinophilin PDZ domain
Descriptor: Neurabin-2
Authors:Kelker, M.S, Peti, W.
Deposit date:2006-02-23
Release date:2007-01-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural basis for spinophilin-neurabin receptor interaction.
Biochemistry, 46, 2007
2G2L
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BU of 2g2l by Molmil
Crystal Structure of the Second PDZ Domain of SAP97 in Complex with a GluR-A C-terminal Peptide
Descriptor: 18-mer peptide from glutamate receptor, ionotropic, AMPA1, ...
Authors:Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K.
Deposit date:2006-02-16
Release date:2006-08-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide
Febs J., 273, 2006
4OEP
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BU of 4oep by Molmil
Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin1 C-terminal tail
Descriptor: ACETATE ION, DODECAETHYLENE GLYCOL, Tight junction protein ZO-1
Authors:Nomme, J, Lavie, A.
Deposit date:2014-01-13
Release date:2015-01-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins.
J.Biol.Chem., 290, 2015
5E21
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BU of 5e21 by Molmil
PDZ2 of LNX2 at 277K,single conformer model
Descriptor: Ligand of Numb protein X 2
Authors:Hekstra, D.R, White, K.I, Socolich, M.A, Ranganathan, R.
Deposit date:2015-09-30
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.011 Å)
Cite:Electric-field-stimulated protein mechanics.
Nature, 540, 2016
5OAK
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BU of 5oak by Molmil
Structure of the dmPar3 PDZ1 domain in complex with the dmPar6 PBM
Descriptor: Bazooka, isoform C,LD29223p, GLYCEROL
Authors:Bruekner, S.R, Wiesner, S.
Deposit date:2017-06-22
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for the interaction between the cell polarity proteins Par3 and Par6.
Sci Signal, 11, 2018
1MFG
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BU of 1mfg by Molmil
The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
Descriptor: Erb-B2 INTERACTING PROTEIN, Erb-B2 carboxyl-terminal fragment
Authors:Birrane, G, Chung, J, Ladias, J.A.
Deposit date:2002-08-10
Release date:2003-01-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
1MFL
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BU of 1mfl by Molmil
The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
Descriptor: Erb-B2 INTERACTING PROTEIN, PHOSPHORYLATED Erb-B2 carboxyl-terminal fragment.
Authors:Birrane, G, Chung, J, Ladias, J.A.
Deposit date:2002-08-12
Release date:2003-01-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
7RM8
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BU of 7rm8 by Molmil
Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide
Descriptor: Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion
Authors:Healy, M.D, Collins, B.M, Mobli, M.
Deposit date:2021-07-26
Release date:2022-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins.
Structure, 30, 2022
8GI4
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BU of 8gi4 by Molmil
Crystal structure of human LIMK2 PDZ domain
Descriptor: LIM domain kinase 2
Authors:Casanova Sepulveda, G, Boggon, T.J.
Deposit date:2023-03-13
Release date:2023-12-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Autoregulation of the LIM kinases by their PDZ domain.
Nat Commun, 14, 2023
1MC7
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BU of 1mc7 by Molmil
Solution Structure of mDvl1 PDZ domain
Descriptor: Segment polarity protein dishevelled homolog DVL-1
Authors:Wong, H.-C, Bourdelas, A, Shao, Y, Wu, D, Shi, D.L, Zheng, J.
Deposit date:2002-08-05
Release date:2003-09-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
Mol.Cell, 12, 2003
7R2M
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BU of 7r2m by Molmil
SYNJ2BP complex with a synthetic Vangl2 peptide (9mer).
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, GLYCEROL, ...
Authors:Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G.
Deposit date:2022-02-04
Release date:2023-05-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide.
To Be Published
7R2T
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BU of 7r2t by Molmil
SYNJ2BP complex with a phosphorylated Vangl2 peptide at the P-1 position.
Descriptor: CALCIUM ION, GLYCEROL, Synaptojanin-2-binding protein,Annexin, ...
Authors:Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G.
Deposit date:2022-02-05
Release date:2023-05-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide.
To Be Published
7MFW
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BU of 7mfw by Molmil
Drosophila melanogaster Canoe PDZ domain in complex with Echinoid C-terminal region
Descriptor: Canoe,Echinoid
Authors:Slep, K.C, Peifer, M, Byrnes, A.E.
Deposit date:2021-04-11
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis.
J.Cell Biol., 220, 2021
1BE9
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BU of 1be9 by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT.
Descriptor: CRIPT, PSD-95
Authors:Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
Deposit date:1998-05-20
Release date:1998-10-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
8HCK
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BU of 8hck by Molmil
NMR fragment-based screening against the two PDZ do-mains of MDA-9
Descriptor: 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE, GLYCEROL, SULFATE ION, ...
Authors:Tang, H.
Deposit date:2022-11-01
Release date:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:NMR fragment-based screening against the two PDZ do-mains of MDA-9
To Be Published

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