2R9J
 
 | | Ligand recognition in C-lobe: The crystal structure of the complex of lactoferrin C-lobe with nicotinamide at 2.5 A resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... | | Authors: | Mir, R, Vikram, G, Singh, N, Kumar, S, Sinha, M, Sharma, S, Kaur, P, Singh, T.P. | | Deposit date: | 2007-09-13 | | Release date: | 2007-10-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Ligand recognition in C-lobe: The crystal structure of the complex of lactoferrin C-lobe with nicotinamide at 2.5 A resolution
To be Published
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8X3H
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1IEJ
 | | OVOTRANSFERRIN, N-TERMINAL LOBE, HOLO FORM, AT 1.65 A RESOLUTION | | Descriptor: | CARBONATE ION, FE (III) ION, OVOTRANSFERRIN | | Authors: | Mizutani, K, Mikami, B, Hirose, M. | | Deposit date: | 2001-04-10 | | Release date: | 2001-06-20 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Domain closure mechanism in transferrins: new viewpoints about the hinge structure and motion as deduced from high resolution crystal structures of ovotransferrin N-lobe.
J.Mol.Biol., 309, 2001
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1CB6
 | | STRUCTURE OF HUMAN APOLACTOFERRIN AT 2.0 A RESOLUTION. | | Descriptor: | CHLORIDE ION, Lactotransferrin | | Authors: | Jameson, G.B, Anderson, B.F, Norris, G.E, Thomas, D.H, Baker, E.N. | | Deposit date: | 1999-03-01 | | Release date: | 1999-03-12 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change.
Acta Crystallogr.,Sect.D, 54, 1998
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4X1D
 | | Ytterbium-bound human serum transferrin | | Descriptor: | GLYCEROL, MALONATE ION, Serotransferrin, ... | | Authors: | Wang, M, Zhang, H, Sun, H. | | Deposit date: | 2014-11-24 | | Release date: | 2015-04-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | "Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
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8FEI
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3MJN
 | | Crystal Structure of the complex of C-lobe of lactoferrin with isopropylamino-3-(1-naphthyloxy)propan-2-ol at 2.38 A Resolution | | Descriptor: | (1E,2R)-1-(ISOPROPYLIMINO)-3-(1-NAPHTHYLOXY)PROPAN-2-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... | | Authors: | Srivastava, K, Vikram, G, Kaushik, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | Deposit date: | 2010-04-13 | | Release date: | 2010-06-30 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Crystal Structure of the complex of C-lobe of lactoferrin with isopropylamino-3-(1-naphthyloxy)propan-2-ol at 2.38 A Resolution
To be Published
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5CRY
 | | Structure of iron-saturated C-lobe of bovine lactoferrin at pH 6.8 indicates the softening of iron coordination | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, FE (III) ION, ... | | Authors: | Singh, A, Rastogi, N, Singh, P.K, Tyagi, T.K, Kaur, P, Sharma, S, Singh, T.P. | | Deposit date: | 2015-07-23 | | Release date: | 2015-10-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Structure of iron-saturated C-lobe of bovine lactoferrin at pH 7.0 indicates the softening of iron coordination
To Be Published
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4OQO
 | | Crystal structure of the tryptic generated iron-free C-lobe of bovine Lactoferrin at 2.42 Angstrom resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lactotransferrin | | Authors: | Singh, A, Rastogi, N, Pandey, S, Bhushan, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | Deposit date: | 2014-02-10 | | Release date: | 2014-03-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Structure of the iron-free true C-terminal half of bovine lactoferrin produced by tryptic digestion and its functional significance in the gut.
Febs J., 281, 2014
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4X1B
 | | Human serum transferrin with ferric ion bound at the C-lobe only | | Descriptor: | FE (III) ION, GLYCEROL, MALONATE ION, ... | | Authors: | Wang, M, Zhang, H, Sun, H. | | Deposit date: | 2014-11-24 | | Release date: | 2015-04-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | "Anion clamp" allows flexible protein to impose coordination geometry on metal ions
Chem.Commun.(Camb.), 51, 2015
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8BRC
 | | Crystal structure of the adduct between human serum transferrin and cisplatin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIA, FE (III) ION, ... | | Authors: | Troisi, R, Galardo, F, Ferraro, G, Sica, F, Merlino, A. | | Deposit date: | 2022-11-22 | | Release date: | 2023-01-18 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study.
Inorg.Chem., 62, 2023
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7Q1L
 | | Glycosilated Human Serum Apo-tranferrin | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | Authors: | Gavira, J.A, Moreno, A, Campos-Escamilla, C, Gonzalez-Ramirez, L.A, Siliqi, D. | | Deposit date: | 2021-10-20 | | Release date: | 2022-03-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin.
Int J Mol Sci, 22, 2021
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6UJ6
 | | X-ray Crystal Structure of Chromium-transferrin with Synergistic Anion Malonate | | Descriptor: | BICARBONATE ION, CHROMIUM ION, GLYCEROL, ... | | Authors: | Petersen, C.M, Edwards, K.C, Gilbert, N.C, Vincent, J.B, Thompson, M.K. | | Deposit date: | 2019-10-02 | | Release date: | 2020-09-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | X-ray structure of chromium(III)-containing transferrin: First structure of a physiological Cr(III)-binding protein.
J.Inorg.Biochem., 210, 2020
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6JAS
 | | Human serum transferrin with iron citrate bound | | Descriptor: | CITRIC ACID, FE (III) ION, MALONATE ION, ... | | Authors: | Wang, M, Wang, H, Sun, H. | | Deposit date: | 2019-01-25 | | Release date: | 2020-01-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Binding of ruthenium and osmium at non-iron sites of transferrin explains their iron-independent cellular uptake
To Be Published
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6WB6
 | | 2.05 A resolution structure of transferrin 1 from Manduca sexta | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | | Authors: | Lovell, S, Kashipathy, M.M, Battaile, K.P, Weber, J.J, Gorman, M.J. | | Deposit date: | 2020-03-26 | | Release date: | 2020-11-25 | | Last modified: | 2021-03-03 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural insight into the novel iron-coordination and domain interactions of transferrin-1 from a model insect, Manduca sexta.
Protein Sci., 30, 2021
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3MC2
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1SDX
 | | Crystal structure of the zinc saturated C-terminal half of bovine lactoferrin at 2.0 A resolution reveals two additional zinc binding sites | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, Lactotransferrin, ... | | Authors: | Jabeen, T, Sharma, S, Singhal, G, Singh, N, Singh, T.P. | | Deposit date: | 2004-02-15 | | Release date: | 2004-03-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structure of the zinc-saturated C-terminal lobe of bovine lactoferrin at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 61, 2005
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3O97
 | | Crystal Structure of the complex of C-lobe of lactoferrin with indole acetic acid at 2.68 A Resolution | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Shukla, P.K, Sinha, M, Bhushan, A, Vikram, G, Kaur, P, Sharma, S, Singh, T.P. | | Deposit date: | 2010-08-04 | | Release date: | 2010-09-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Crystal Structure of the complex of C-lobe of lactoferrin with indole acetic acid at 2.68 A Resolution
To be Published
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1SQY
 | | Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | | Authors: | Vikram, P, Prem Kumar, R, Singh, N, Kumar, J, Ethayathulla, A.S, Sharma, S, Kaur, P, Singh, T.P. | | Deposit date: | 2004-03-22 | | Release date: | 2004-04-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5.
To be Published
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3FGS
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6XR0
 | | Crystal Structure of Human Melanotransferrin in complex with SC57.32 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, ... | | Authors: | Hayashi, K, Longenecker, K.L, Vivona, S. | | Deposit date: | 2020-07-10 | | Release date: | 2021-01-20 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.064 Å) | | Cite: | Complex of human Melanotransferrin and SC57.32 Fab fragment reveals novel interdomain arrangement with ferric N-lobe and open C-lobe.
Sci Rep, 11, 2021
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3E9X
 | | Crystal Structure of the Complex of C-lobe of Lactoferrin with Nimesulide at 2.7 A Resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-NITRO-2-PHENOXYMETHANESULFONANILIDE, CARBONATE ION, ... | | Authors: | Mir, R, Balaji, K, Vikram, G, Sinha, M, Singh, N, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. | | Deposit date: | 2008-08-24 | | Release date: | 2008-09-23 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure of the Complex of C-lobe of Lactoferrin with Nimesulide at 2.7 A Resolution
To be Published
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7ENU
 | | Crystal structure of iron-saturated C-terminal half of lactoferrin produced proteolytically using pepsin at 2.32A resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | | Authors: | Singh, J, Maurya, A, Viswanathan, V, Singh, P.K, Sharma, P, Sharma, S, Singh, T.P. | | Deposit date: | 2021-04-19 | | Release date: | 2021-05-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.322 Å) | | Cite: | Crystal structure of iron-saturated C-terminal half of lactoferrin produced proteolytically using pepsin at 2.32A resolution
To Be Published
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4NED
 | | Crystal STRUCTURE OF C-LOBE OF BOVINE LACTOFERRIN COMPLEXED WITH FENOPROFEN AT 2.1 ANGSTROM RESOLUTION | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... | | Authors: | Gautam, L, Dube, D, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | Deposit date: | 2013-10-29 | | Release date: | 2013-12-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal STRUCTURE OF C-LOBE OF BOVINE LACTOFERRIN COMPLEXED WITH FENOPROFEN AT 2.1 ANGSTROM RESOLUTION
To be Published
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4N6P
 | | Crystal Structure of C-lobe of Bovine lactoferrin complexed with meclofenamic acid at 1.4 A resolution | | Descriptor: | 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Gautam, L, Dube, D, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | | Deposit date: | 2013-10-14 | | Release date: | 2013-10-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structre of C-LOBE OF BOVINE LACTOFERRIN COMPLEXED WITH MECLOFENAMIC ACID AT 1.4 A RESOLUTION
TO BE PUBLISHED
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