7TL4
 
 | | Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 6YF | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER | | Authors: | Blee, A.M, Salay, L.E, Chazin, W.J. | | Deposit date: | 2022-01-18 | | Release date: | 2022-06-29 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.805 Å) | | Cite: | Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
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7TL2
 | | Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF412 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ... | | Authors: | Blee, A.M, Salay, L.E, Chazin, W.J. | | Deposit date: | 2022-01-18 | | Release date: | 2022-06-29 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.529 Å) | | Cite: | Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
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5OL0
 | | Structure of Leishmania infantum Silent Information Regulator 2 related protein 1 (LiSIR2rp1) in complex with acetylated p53 peptide | | Descriptor: | Cellular tumor antigen p53, Putative silent information regulator 2,Putative silent information regulator 2, ZINC ION | | Authors: | Ronin, C, Ciesielski, F, Ciapetti, P. | | Deposit date: | 2017-07-26 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design.
PLoS ONE, 13, 2018
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8EPK
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1T8T
 | | Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP | | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, CITRIC ACID, heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1 | | Authors: | Moon, A.F, Edavettal, S.C, Krahn, J.M, Munoz, E.M, Negishi, M, Linhardt, R.J, Liu, J, Pedersen, L.C. | | Deposit date: | 2004-05-13 | | Release date: | 2004-08-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1
J.Biol.Chem., 279, 2004
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1T2R
 | | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | | Descriptor: | 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2 | | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | | Deposit date: | 2004-04-22 | | Release date: | 2004-06-01 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
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3C5G
 | | Structure of a ternary complex of the R517K Pol lambda mutant | | Descriptor: | 1,2-ETHANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*DCP*DAP*DGP*DTP*DAP*(2DT))-3'), ... | | Authors: | Garcia-Diaz, M, Bebenek, K, Foley, M.C, Pedersen, L.C, Schlick, T, Kunkel, T.A. | | Deposit date: | 2008-01-31 | | Release date: | 2008-07-29 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda.
Embo Rep., 9, 2008
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3U3I
 | | A RNA binding protein from Crimean-Congo hemorrhagic fever virus | | Descriptor: | Nucleocapsid protein | | Authors: | Guo, Y, Wang, W.M, Ji, W, Deng, M, Sun, Y.N, Lou, Z.Y, Rao, Z.H. | | Deposit date: | 2011-10-06 | | Release date: | 2012-03-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.304 Å) | | Cite: | Crimean-Congo hemorrhagic fever virus nucleoprotein reveals endonuclease activity in bunyaviruses
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FXH
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3D3K
 | | Crystal structure of human Edc3p | | Descriptor: | Enhancer of mRNA-decapping protein 3 | | Authors: | Ling, S.H.M. | | Deposit date: | 2008-05-12 | | Release date: | 2008-08-26 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of human Edc3 and its functional implications
Mol.Cell.Biol., 28, 2008
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1TLH
 | | T4 AsiA bound to sigma70 region 4 | | Descriptor: | 10 kDa anti-sigma factor, RNA polymerase sigma factor rpoD | | Authors: | Lambert, L.J, Wei, Y, Schirf, V, Demeler, B, Werner, M.H. | | Deposit date: | 2004-06-09 | | Release date: | 2004-11-23 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | T4 AsiA blocks DNA recognition by remodeling sigma(70) region 4
Embo J., 23, 2004
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4FXE
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1EK8
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2FSF
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2FSI
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2FQY
 | | PnrA from Treponema pallidum complexed with adenosine. | | Descriptor: | ADENOSINE, Membrane lipoprotein tmpC | | Authors: | Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V. | | Deposit date: | 2006-01-18 | | Release date: | 2006-02-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum
J.Biol.Chem., 281, 2006
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2FSH
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6AF0
 | | Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila | | Descriptor: | Cdc73 protein, Ctr9 protein, Paf1 protein | | Authors: | Wang, Z, Deng, P, Zhou, Y. | | Deposit date: | 2018-08-07 | | Release date: | 2018-09-19 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1IYS
 | | Crystal Structure of Class A beta-Lactamase Toho-1 | | Descriptor: | BETA-LACTAMASE TOHO-1, SULFATE ION | | Authors: | Ibuka, A.S, Ishii, Y, Yamaguchi, K, Matsuzawa, H, Sakai, H. | | Deposit date: | 2002-09-06 | | Release date: | 2003-10-14 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal Structure of Extended-Spectrum beta-Lactamase Toho-1: Insights into the Molecular Mechanism for
Catalytic Reaction and Substrate Specificity Expansion
Biochemistry, 42, 2003
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4ERL
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1F2N
 | | RICE YELLOW MOTTLE VIRUS | | Descriptor: | CALCIUM ION, CAPSID PROTEIN | | Authors: | Qu, C, Liljas, L, Opalka, N, Brugidou, C, Yeager, M, Beachy, R.N, Fauquet, C.M, Johnson, J.E, Lin, T. | | Deposit date: | 2000-05-26 | | Release date: | 2000-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | 3D domain swapping modulates the stability of members of an icosahedral virus group.
Structure Fold.Des., 8, 2000
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5M1R
 | | X-ray structure of human G166D PGK-1 mutant | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoglycerate kinase 1 | | Authors: | Ilari, A, Cipollone, A, Fiorillo, A, Petrosino, M. | | Deposit date: | 2016-10-10 | | Release date: | 2017-12-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.
PLoS ONE, 13, 2018
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5MXM
 | | The X-ray structure of human M190I phosphoglycerate kinase 1 mutant | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Ilari, A, Fiorillo, A, Cipollone, A, Petrosino, M. | | Deposit date: | 2017-01-23 | | Release date: | 2018-02-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.
PLoS ONE, 13, 2018
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2IS2
 | | Crystal structure of UvrD-DNA binary complex | | Descriptor: | 33-MER, DNA helicase II, FORMIC ACID, ... | | Authors: | Yang, W, Lee, J.Y. | | Deposit date: | 2006-10-16 | | Release date: | 2007-01-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
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4QT0
 | | Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 1, 3-{[3-CARBAMOYL-7-(2,4-DIMETHOXYPYRIMIDIN-5-YL)QUINOLIN-4-YL]AMINO}BENZOIC ACID | | Descriptor: | 3-{[3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl]amino}benzoic acid, L-lactate dehydrogenase A chain | | Authors: | Kolappan, S, Craig, L. | | Deposit date: | 2014-07-06 | | Release date: | 2014-12-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
Acta Crystallogr.,Sect.D, 71, 2015
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