5M1R
X-ray structure of human G166D PGK-1 mutant
Summary for 5M1R
Entry DOI | 10.2210/pdb5m1r/pdb |
Descriptor | Phosphoglycerate kinase 1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | phosphoglycerate kinase, single nucleotide polymorphism derived mutant g166d, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 45075.27 |
Authors | Ilari, A.,Cipollone, A.,Fiorillo, A.,Petrosino, M. (deposition date: 2016-10-10, release date: 2017-12-20, Last modification date: 2024-01-17) |
Primary citation | Fiorillo, A.,Petrosino, M.,Ilari, A.,Pasquo, A.,Cipollone, A.,Maggi, M.,Chiaraluce, R.,Consalvi, V. The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme. PLoS ONE, 13:e0199191-e0199191, 2018 Cited by PubMed: 29995887DOI: 10.1371/journal.pone.0199191 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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