5MXM
The X-ray structure of human M190I phosphoglycerate kinase 1 mutant
Summary for 5MXM
| Entry DOI | 10.2210/pdb5mxm/pdb |
| Related | 5M3U |
| Descriptor | Phosphoglycerate kinase 1, MAGNESIUM ION, 3-PHOSPHOGLYCERIC ACID, ... (6 entities in total) |
| Functional Keywords | transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 45370.19 |
| Authors | Ilari, A.,Fiorillo, A.,Cipollone, A.,Petrosino, M. (deposition date: 2017-01-23, release date: 2018-02-14, Last modification date: 2019-10-16) |
| Primary citation | Fiorillo, A.,Petrosino, M.,Ilari, A.,Pasquo, A.,Cipollone, A.,Maggi, M.,Chiaraluce, R.,Consalvi, V. The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme. PLoS ONE, 13:e0199191-e0199191, 2018 Cited by PubMed: 29995887DOI: 10.1371/journal.pone.0199191 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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