5OL0

Structure of Leishmania infantum Silent Information Regulator 2 related protein 1 (LiSIR2rp1) in complex with acetylated p53 peptide

Summary for 5OL0

• Entry DOI: 10.2210/pdb5ol0/pdb
• Descriptor: Putative silent information regulator 2,Putative silent information regulator 2, Cellular tumor antigen p53, ZINC ION, ... (4 entities in total)
• Functional Keywords: nad-dependent histone deacetylase, hydrolase
• Biological source: Leishmania infantum; More
• Cellular location: Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
• Total number of polymer chains: 4
• Total formula weight: 75156.16

Authors

Ronin, C.,Ciesielski, F.,Ciapetti, P. (deposition date: 2017-07-26, release date: 2018-02-28, Last modification date: 2024-01-17)

• Primary citation: Ronin, C.,Costa, D.M.,Tavares, J.,Faria, J.,Ciesielski, F.,Ciapetti, P.,Smith, T.K.,MacDougall, J.,Cordeiro-da-Silva, A.,Pemberton, I.K.; The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design.; PLoS ONE, 13:e0193602-e0193602, 2018; PubMed: 29543820; DOI: 10.1371/journal.pone.0193602

Experimental method

X-RAY DIFFRACTION (1.99 Å)