5OL0
Structure of Leishmania infantum Silent Information Regulator 2 related protein 1 (LiSIR2rp1) in complex with acetylated p53 peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
| A | 0051287 | molecular_function | NAD binding |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
| B | 0051287 | molecular_function | NAD binding |
| B | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | CYS152 |
| A | CYS155 |
| A | CYS176 |
| A | CYS179 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1001 |
| Chain | Residue |
| B | CYS152 |
| B | CYS155 |
| B | CYS176 |
| B | CYS179 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; by SETD7 => ECO:0000269|PubMed:15525938, ECO:0000269|PubMed:16415881 |
| Chain | Residue | Details |
| C | LYS372 | |
| D | LYS372 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0000269|PubMed:10656795 |
| Chain | Residue | Details |
| C | LYS373 | |
| D | LYS373 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:29474172, ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| C | LYS381 | |
| D | LYS381 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; by KMT5A; alternate => ECO:0000269|PubMed:17707234, ECO:0000269|PubMed:20870725, ECO:0000269|PubMed:22864287 |
| Chain | Residue | Details |
| C | ALY382 | |
| D | ALY382 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:11124955, ECO:0000269|PubMed:22214662, ECO:0000269|Ref.37 |
| Chain | Residue | Details |
| C | LYS386 | |
| D | LYS386 |
