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5OL0

Structure of Leishmania infantum Silent Information Regulator 2 related protein 1 (LiSIR2rp1) in complex with acetylated p53 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Putative silent information regulator 2,Putative silent information regulator 2polymer32435373.22UniProt (Q8I6E4)
Pfam (PF02146)
UniProt (by SIFTS) (A0A6L0XH39)
Leishmania infantumSIR2-like protein,SIR2-like protein
2C, D
(C, D)
Cellular tumor antigen p53polymer182139.52UniProt (P04637)Homo sapiensAntigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53
3E, F
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
4G, H, I, J
(A, B, C, D)
waterwater18.0239Chemie (HOH)
Sequence modifications
A, B: 1 - 252 (UniProt: Q8I6E4)
PDBExternal DatabaseDetails
Gly -1-expression tag
His 0-expression tag
A, B: 304 - 373 (UniProt: Q8I6E4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight75025.3
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight75156.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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