4ZN9
| Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with Oxabicyclic Heptene Sulfonate (OBHS) | Descriptor: | Estrogen receptor, Nuclear receptor-interacting peptide, cyclohexa-2,5-dien-1-yl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate | Authors: | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | Deposit date: | 2015-05-04 | Release date: | 2015-09-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.215 Å) | Cite: | Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands. Chemmedchem, 7, 2012
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1E41
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1DFB
| STRUCTURE OF A HUMAN MONOCLONAL ANTIBODY FAB FRAGMENT AGAINST GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE I | Descriptor: | IGG1-KAPPA 3D6 FAB (HEAVY CHAIN), IGG1-KAPPA 3D6 FAB (LIGHT CHAIN) | Authors: | He, X.M, Rueker, F, Casale, E, Carter, D.C. | Deposit date: | 1992-03-27 | Release date: | 1993-10-31 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of a human monoclonal antibody Fab fragment against gp41 of human immunodeficiency virus type 1. Proc.Natl.Acad.Sci.USA, 89, 1992
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1PM6
| Solution Structure of Full-Length Excisionase (Xis) from Bacteriophage HK022 | Descriptor: | Excisionase | Authors: | Rogov, V.V, Luecke, C, Muresanu, L, Wienk, H, Kleinhaus, I, Werner, K, Loehr, F, Pristovsek, P, Rueterjans, H. | Deposit date: | 2003-06-10 | Release date: | 2003-12-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure and stability of the full-length excisionase from bacteriophage HK022. Eur.J.Biochem., 270, 2003
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6IDM
| Crystal structure of Peptidoglycan recognition protein (PGRP-S) with Tartaric acid at 3.20 A resolution | Descriptor: | L(+)-TARTARIC ACID, Peptidoglycan recognition protein 1 | Authors: | Bairagya, H.R, Shokeen, A, Sharma, P, Singh, P.K, Sharma, S, Singh, T.P. | Deposit date: | 2018-09-10 | Release date: | 2018-09-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of Peptidoglycan recognition protein (PGRP-S) with Tartaric acid at 3.20 A resolution To Be Published
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6IK9
| HIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:dGTP ternary complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2018-10-15 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.435 Å) | Cite: | Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors. Biochem. Biophys. Res. Commun., 509, 2019
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7XY9
| Cryo-EM structure of secondary alcohol dehydrogenases TbSADH after carrier-free immobilization based on weak intermolecular interactions | Descriptor: | MAGNESIUM ION, NADP-dependent isopropanol dehydrogenase, ZINC ION | Authors: | Chen, Q, Li, X, Yang, F, Qu, G, Sun, Z.T, Wang, Y.J. | Deposit date: | 2022-06-01 | Release date: | 2023-06-07 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.12 Å) | Cite: | Active and stable alcohol dehydrogenase-assembled hydrogels via synergistic bridging of triazoles and metal ions. Nat Commun, 14, 2023
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1PVG
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2CB5
| HUMAN BLEOMYCIN HYDROLASE, C73S/DELE455 MUTANT | Descriptor: | PROTEIN (BLEOMYCIN HYDROLASE) | Authors: | O'Farrell, P.A, Gonzalez, F, Zheng, W, Johnston, S.A, Joshua-Tor, L. | Deposit date: | 1999-03-02 | Release date: | 2000-03-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease. Structure Fold.Des., 7, 1999
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5TY3
| Crystal structure of K72A variant of Human Cytochrome c | Descriptor: | Cytochrome c, HEME C, SULFATE ION | Authors: | Mou, T.C, Nold, S.M, Lei, H, Sprang, S.R, Bowler, B.E. | Deposit date: | 2016-11-18 | Release date: | 2017-09-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Effect of a K72A Mutation on the Structure, Stability, Dynamics, and Peroxidase Activity of Human Cytochrome c. Biochemistry, 56, 2017
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6SWM
| selenol bound carbonic anhydrase I | Descriptor: | (2~{R})-1-prop-2-enoxy-3-selanyl-propan-2-ol, Carbonic anhydrase 1, ZINC ION | Authors: | Angeli, A, Ferraroni, M. | Deposit date: | 2019-09-22 | Release date: | 2020-10-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Selenols: a new class of carbonic anhydrase inhibitors. Chem.Commun.(Camb.), 55, 2019
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6I9H
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6SZH
| Acinetobacter baumannii undecaprenyl pyrophosphate synthase (AB-UppS) in complex with GW197 | Descriptor: | 3,5-dimethyl-1~{H}-pyrrole-2-carbonitrile, CALCIUM ION, Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | Authors: | Thorpe, J.H. | Deposit date: | 2019-10-02 | Release date: | 2020-01-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Cocktailed fragment screening by X-ray crystallography of the antibacterial target undecaprenyl pyrophosphate synthase from Acinetobacter baumannii. Acta Crystallogr.,Sect.F, 76, 2020
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5U5P
| Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus Musculus Complexed with a MLH1 NLS Peptide | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA mismatch repair protein Mlh1, Importin subunit alpha-1 | Authors: | Barros, A.C, Takeda, A.A, Dreyer, T.R, Velazquez-Campoy, A, Kobe, B, Fontes, M.R. | Deposit date: | 2016-12-07 | Release date: | 2018-03-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.171 Å) | Cite: | DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway. Biochimie, 146, 2018
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6GHM
| Structure of PP1 alpha phosphatase bound to ASPP2 | Descriptor: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Apoptosis-stimulating of p53 protein 2, ... | Authors: | Mouilleron, S, Bertran, T.M, Tapon, N, Zhou, Y. | Deposit date: | 2018-05-08 | Release date: | 2019-02-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail. Nat Commun, 10, 2019
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5LFN
| Crystal structure of human chondroadherin | Descriptor: | CHLORIDE ION, Chondroadherin | Authors: | Ramisch, S, Pramhed, A, Logan, D.T. | Deposit date: | 2016-07-03 | Release date: | 2016-12-28 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human chondroadherin: solving a difficult molecular-replacement problem using de novo models. Acta Crystallogr D Struct Biol, 73, 2017
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3BOM
| Crystal structure of trout hemoglobin at 1.35 Angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, Hemoglobin subunit alpha-4, Hemoglobin subunit beta-4, ... | Authors: | Aranda IV, R, Bingman, C.A, Bitto, E, Wesenberg, G.E, Richards, M, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-12-17 | Release date: | 2008-01-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Trout Hemoglobin Crystal Structure at 1.35 Angstroms Resolution. To be Published
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2CRT
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4O1K
| Crystal structures of two tetrameric beta-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora. | Descriptor: | Carbonic anhydrase, ZINC ION | Authors: | Lehneck, R, Neumann, P, Vullo, D, Elleuche, S, Supuran, C.T, Ficner, R, Poggeler, S. | Deposit date: | 2013-12-16 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal structures of two tetrameric beta-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora. Febs J., 281, 2014
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1UOR
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1O3Z
| HIV-1 DIS(MAL) DUPLEX RU HEXAMINE-SOAKED | Descriptor: | HIV-1 DIS(MAL) GENOMIC RNA, MAGNESIUM ION, RUTHENIUM ION | Authors: | Ennifar, E, Walter, P, Dumas, P. | Deposit date: | 2003-05-16 | Release date: | 2003-05-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | A crystallographic study of the binding of 13 metal ions to two related RNA duplexes. Nucleic Acids Res., 31, 2003
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1MPP
| X-RAY ANALYSES OF ASPARTIC PROTEINASES. V. STRUCTURE AND REFINEMENT AT 2.0 ANGSTROMS RESOLUTION OF THE ASPARTIC PROTEINASE FROM MUCOR PUSILLUS | Descriptor: | PEPSIN, SULFATE ION | Authors: | Newman, M, Watson, F, Roychowdhury, P, Jones, H, Badasso, M, Cleasby, A, Wood, S.P, Tickle, I.J, Blundell, T.L. | Deposit date: | 1992-02-19 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray analyses of aspartic proteinases. V. Structure and refinement at 2.0 A resolution of the aspartic proteinase from Mucor pusillus. J.Mol.Biol., 230, 1993
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5T8Q
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6GUA
| Xylulose 5-phosphate phosphoketolase from Lactococcus lactis | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, Probable phosphoketolase, ... | Authors: | Scheidig, A.J, Szedlacsek, S.E. | Deposit date: | 2018-06-19 | Release date: | 2019-05-22 | Last modified: | 2024-01-17 | Method: | SOLUTION SCATTERING (1.95 Å), X-RAY DIFFRACTION | Cite: | Crystal structure of a xylulose 5-phosphate phosphoketolase. Insights into the substrate specificity for xylulose 5-phosphate. J.Struct.Biol., 207, 2019
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6GH7
| WILDTYPE CORE-STREPTAVIDIN WITH a conjugated BIOTINYLATED PYRROLIDINE | Descriptor: | 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[(3~{R})-pyrrolidin-3-yl]pentanamide, Streptavidin | Authors: | Nodling, A.R, Tsai, Y.H, Luk, L.Y.P, Rizkallah, P, Jin, Y. | Deposit date: | 2018-05-04 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Reactivity and Selectivity of Iminium Organocatalysis Improved by a Protein Host. Angew.Chem.Int.Ed.Engl., 57, 2018
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