6GH7

WILDTYPE CORE-STREPTAVIDIN WITH a conjugated BIOTINYLATED PYRROLIDINE

Summary for 6GH7

• Entry DOI: 10.2210/pdb6gh7/pdb
• Descriptor: Streptavidin, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[(3~{R})-pyrrolidin-3-yl]pentanamide (3 entities in total)
• Functional Keywords: biotin-binding protein, organocatalysis, supramolecular chemistry, secondary amine, artificial enzyme
• Biological source: Streptomyces avidinii
• Total number of polymer chains: 4
• Total formula weight: 54899.85

Authors

Nodling, A.R.,Tsai, Y.H.,Luk, L.Y.P.,Rizkallah, P.,Jin, Y. (deposition date: 2018-05-04, release date: 2018-10-10, Last modification date: 2024-01-17)

• Primary citation: Nodling, A.R.,Swiderek, K.,Castillo, R.,Hall, J.W.,Angelastro, A.,Morrill, L.C.,Jin, Y.,Tsai, Y.H.,Moliner, V.,Luk, L.Y.P.; Reactivity and Selectivity of Iminium Organocatalysis Improved by a Protein Host.; Angew.Chem.Int.Ed.Engl., 57:12478-12482, 2018; PubMed: 30027571; DOI: 10.1002/anie.201806850

Experimental method

X-RAY DIFFRACTION (1.08 Å)