5U5P

Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus Musculus Complexed with a MLH1 NLS Peptide

Summary for 5U5P

• Entry DOI: 10.2210/pdb5u5p/pdb
• Related: 5U5R
• Descriptor: DNA mismatch repair protein Mlh1, Importin subunit alpha-1, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (4 entities in total)
• Functional Keywords: nuclear transport, importin-alpha, mlh1, nls, transport protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 58083.66

Authors

Barros, A.C.,Takeda, A.A.,Dreyer, T.R.,Velazquez-Campoy, A.,Kobe, B.,Fontes, M.R. (deposition date: 2016-12-07, release date: 2018-03-14, Last modification date: 2023-10-04)

• Primary citation: de Barros, A.C.,Takeda, A.A.S.,Dreyer, T.R.,Velazquez-Campoy, A.,Kobe, B.,Fontes, M.R.M.; DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway.; Biochimie, 146:87-96, 2018; PubMed: 29175432; DOI: 10.1016/j.biochi.2017.11.013

Experimental method

X-RAY DIFFRACTION (2.171 Å)