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1HAX
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BU of 1hax by Molmil
Snapshots of serine protease catalysis: (A) acyl-enzyme intermediate between porcine pancreatic elastase and human beta-casomorphin-7 at pH 5
Descriptor: BETA-CASOMORPHIN-7, CALCIUM ION, ELASTASE 1, ...
Authors:Wilmouth, R.C, Edman, K, Neutze, R, Wright, P.A, Clifton, I.J, Schneider, T.R, Schofield, C.J, Hajdu, J.
Deposit date:2001-04-10
Release date:2001-08-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
8OWU
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BU of 8owu by Molmil
The crystal structure of the polymorphic toxin PT7(Bc) D37A mutant and its cognate immunity PIM7(Bc) complex
Descriptor: MAGNESIUM ION, PIM7, Transposase
Authors:Tzarum, N, Fraenkel, R, Deouell, N, Cahana, I.
Deposit date:2023-04-28
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Systematic Discovery of Antibacterial and Antifungal Bacterial Toxins
To Be Published
8OWS
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BU of 8ows by Molmil
The crystal structure of the polymorphic toxin PT1(Em) H44A mutant and its cognate immunity PIM1(Em) complex
Descriptor: PIM1, Type IV secretion protein Rhs
Authors:Tzarum, N, Fraenkel, R, Deouell, N, Cahana, I.
Deposit date:2023-04-28
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Systematic Discovery of Antibacterial and Antifungal Bacterial Toxins
To Be Published
4Q7O
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BU of 4q7o by Molmil
The crystal structure of an immunity protein NMB0503 from Neisseria meningitidis MC58
Descriptor: BROMIDE ION, FORMIC ACID, Immunity protein
Authors:Tan, K, Stols, L, Eschenfeldt, W, Babnigg, G, Low, D.A, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2014-04-25
Release date:2014-05-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The structure of a contact-dependent growth-inhibition (CDI) immunity protein from Neisseria meningitidis MC58.
Acta Crystallogr F Struct Biol Commun, 71, 2015
7N2G
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BU of 7n2g by Molmil
MicroED structure of human CPEB3 segment(154-161) kinked polymorph phased by ARCIMBOLDO-BORGES
Descriptor: CPEB3
Authors:Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R.
Deposit date:2021-05-29
Release date:2022-06-01
Last modified:2024-05-22
Method:ELECTRON CRYSTALLOGRAPHY (1.201 Å)
Cite:Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
7N2F
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BU of 7n2f by Molmil
MicroED structure of human CPEB3 segment (154-161) straight polymorph phased by ARCIMBOLDO-BORGES
Descriptor: CPEB3
Authors:Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R.
Deposit date:2021-05-29
Release date:2022-06-01
Last modified:2024-05-22
Method:ELECTRON CRYSTALLOGRAPHY (1.2 Å)
Cite:Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
7N2E
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BU of 7n2e by Molmil
MicroED structure of human CPEB3 segment (154-161) straight polymorph
Descriptor: CPEB3
Authors:Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R.
Deposit date:2021-05-29
Release date:2022-06-01
Last modified:2024-05-22
Method:ELECTRON CRYSTALLOGRAPHY (1 Å)
Cite:Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
7NUY
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BU of 7nuy by Molmil
New polymorhp of proteinase K obtained by free interface diffusion technique
Descriptor: Proteinase K, SULFATE ION
Authors:Gavira, J.A, Artusio, F, Castellvi, A, Pisano, R.
Deposit date:2021-03-15
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Tuning Transport Phenomena in Agarose Gels for the Control of Protein Nucleation Density and Crystal Form
Crystals, 2021
7NS7
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BU of 7ns7 by Molmil
Human L-alanine:glyoxylate aminotransferase minor allele variant: AGXT-Mi (P11L-I340M)
Descriptor: L-alanine:glyoxylate aminotransferase
Authors:Cellini, B, Dindo, M.
Deposit date:2021-03-05
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase.
Protein Sci., 31, 2022
4NIX
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BU of 4nix by Molmil
Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) orthorhombic form, zinc-bound
Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL, ...
Authors:Schoepfel, M, Parthier, C, Stubbs, M.T.
Deposit date:2013-11-08
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:N-terminal protein modification by substrate-activated reverse proteolysis.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NIW
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BU of 4niw by Molmil
Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) orthorhombic form
Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL
Authors:Schoepfel, M, Parthier, C, Stubbs, M.T.
Deposit date:2013-11-08
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:N-terminal protein modification by substrate-activated reverse proteolysis.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NFF
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BU of 4nff by Molmil
Human kallikrein-related peptidase 2 in complex with PPACK
Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Kallikrein-2
Authors:Skala, W, Brandstetter, H, Magdolen, V, Goettig, P.
Deposit date:2013-10-31
Release date:2014-10-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity
J.Biol.Chem., 289, 2014
4NIV
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BU of 4niv by Molmil
Crystal structure of trypsiligase (K60E/N143H/Y151H/D189K trypsin) trigonal form
Descriptor: CALCIUM ION, Cationic trypsin, GLYCEROL
Authors:Schoepfel, M, Parthier, C, Stubbs, M.T.
Deposit date:2013-11-08
Release date:2014-02-19
Last modified:2014-03-19
Method:X-RAY DIFFRACTION (1 Å)
Cite:N-terminal protein modification by substrate-activated reverse proteolysis.
Angew.Chem.Int.Ed.Engl., 53, 2014
4NFE
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BU of 4nfe by Molmil
Human kallikrein-related peptidase 2 in complex with benzamidine
Descriptor: BENZAMIDINE, Kallikrein-2, SULFATE ION
Authors:Skala, W, Brandstetter, H, Magdolen, V, Goettig, P.
Deposit date:2013-10-31
Release date:2014-10-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity
J.Biol.Chem., 289, 2014
4DKS
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BU of 4dks by Molmil
A spindle-shaped virus protein (chymotrypsin treated)
Descriptor: Probable integrase
Authors:Ouyang, S, Liang, W, Huang, L, Liu, Z.-J.
Deposit date:2012-02-04
Release date:2012-05-30
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and functional characterization of the C-terminal catalytic domain of SSV1 integrase.
Acta Crystallogr.,Sect.D, 68, 2012
4MWT
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BU of 4mwt by Molmil
Crystal structure of human PPCA (trigonal crystal form 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosomal protective protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Kolli, N, Garman, S.C.
Deposit date:2013-09-25
Release date:2014-03-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Proteolytic activation of human cathepsin A.
J.Biol.Chem., 289, 2014
4GWN
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BU of 4gwn by Molmil
Crystal structure of human mature meprin beta
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X.
Deposit date:2012-09-03
Release date:2012-09-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane
Proc.Natl.Acad.Sci.USA, 109, 2012
3H13
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BU of 3h13 by Molmil
c-FLIPL protease-like domain
Descriptor: CASP8 and FADD-like apoptosis regulator
Authors:Jeffrey, P.D, Yu, J.W, Shi, Y.
Deposit date:2009-04-10
Release date:2009-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of procaspase-8 activation by c-FLIPL.
Proc.Natl.Acad.Sci.USA, 106, 2009
4MWS
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BU of 4mws by Molmil
Crystal structure of human PPCA (trigonal crystal form 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Lysosomal protective protein, ...
Authors:Kolli, N, Garman, S.C.
Deposit date:2013-09-25
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Proteolytic activation of human cathepsin A.
J.Biol.Chem., 289, 2014
4HXD
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BU of 4hxd by Molmil
Diversity of ubiquitin and ISG15 specificity amongst nairoviruses viral ovarian tumor domain proteases
Descriptor: 1.7.6 3-bromanylpropan-1-amine, Polyubiquitin-C, RNA-directed RNA polymerase L, ...
Authors:Capodagli, G.C, Pegan, S.D.
Deposit date:2012-11-09
Release date:2013-02-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Diversity of Ubiquitin and ISG15 Specificity among Nairoviruses' Viral Ovarian Tumor Domain Proteases.
J.Virol., 87, 2013
1WIP
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BU of 1wip by Molmil
STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4, MONOCLINIC CRYSTAL FORM
Descriptor: T-CELL SURFACE GLYCOPROTEIN CD4
Authors:Wu, H, Kwong, P.D, Hendrickson, W.A.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Dimeric association and segmental variability in the structure of human CD4.
Nature, 387, 1997
1P10
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BU of 1p10 by Molmil
STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Bone, R, Agard, D.A.
Deposit date:1989-04-24
Release date:1990-04-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural plasticity broadens the specificity of an engineered protease.
Nature, 339, 1989
3WOR
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BU of 3wor by Molmil
Crystal structure of the DAP BII octapeptide complex
Descriptor: Angiotensin II, GLYCEROL, ZINC ION, ...
Authors:Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
Deposit date:2013-12-29
Release date:2014-09-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3WOP
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BU of 3wop by Molmil
Crystal structure of the DAP BII hexapeptide complex II
Descriptor: Angiotensin IV, GLYCEROL, ZINC ION, ...
Authors:Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
Deposit date:2013-12-29
Release date:2014-09-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014
3WOQ
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BU of 3woq by Molmil
Crystal structure of the DAP BII hexapeptide complex III
Descriptor: Angiotensin IV, GLYCEROL, ZINC ION, ...
Authors:Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Nonaka, T, Ogasawara, W, Tanaka, N.
Deposit date:2013-12-29
Release date:2014-09-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:S46 peptidases are the first exopeptidases to be members of clan PA
SCI REP, 4, 2014

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