PDB: 2849 resultsInfo pagesStatus searchChemie searchBIRD

---

1AGT	SOLUTION STRUCTURE OF THE POTASSIUM CHANNEL INHIBITOR AGITOXIN 2: CALIPER FOR PROBING CHANNEL GEOMETRY Descriptor: AGITOXIN 2 Authors: Krezel, A.M, Kasibhatla, C, Hidalgo, P, Mackinnon, R, Wagner, G. Deposit date: 1995-04-14 Release date: 1995-07-10 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry. Protein Sci., 4, 1995
5YW7	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on SUR1 ABC transporter module at 4.4A) Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
4J9Z	Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and NS309 Descriptor: (3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin, ... Authors: Zhang, M, Pascal, J.M, Zhang, J.-F. Deposit date: 2013-02-17 Release date: 2013-03-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca2+-sensing and SK channel activation. Proc.Natl.Acad.Sci.USA, 110, 2013
5YWD	Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (focused refinement of SUR1 ABC transporter module at 4.22A) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, MAGNESIUM ION Authors: Chen, L, Wu, J.X. Deposit date: 2017-11-29 Release date: 2018-05-02 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
1BGK	SEA ANEMONE TOXIN (BGK) WITH HIGH AFFINITY FOR VOLTAGE DEPENDENT POTASSIUM CHANNEL, NMR, 15 STRUCTURES Descriptor: BGK Authors: Dauplais, M, Lecoq, A, Song, J, Cotton, J, Jamin, N, Gilquin, B, Roumestand, C, Vita, C, Harvey, A, Menez, A. Deposit date: 1996-05-08 Release date: 1997-01-27 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures. J.Biol.Chem., 272, 1997
8DJB	MthK-A90L mutant in closed state with 0 Ca2+ Descriptor: Calcium-gated potassium channel MthK, POTASSIUM ION Authors: Agarwal, S, Nimigean, C.M. Deposit date: 2022-06-30 Release date: 2023-07-05 Last modified: 2024-01-03 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 20, 2024
4J9Y	Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant Descriptor: CALCIUM ION, Calmodulin, GLYCEROL, ... Authors: Zhang, M, Pascal, J.M, Zhang, J.-F. Deposit date: 2013-02-17 Release date: 2013-03-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca2+-sensing and SK channel activation. Proc.Natl.Acad.Sci.USA, 110, 2013
1DSX	KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT Descriptor: PROTEIN (KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL) Authors: Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M. Deposit date: 2000-01-10 Release date: 2000-09-20 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell(Cambridge,Mass.), 102, 2000
2R9R	Shaker family voltage dependent potassium channel (kv1.2-kv2.1 paddle chimera channel) in association with beta subunit Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... Authors: Long, S.B, Tao, X, Campbell, E.B, Mackinnon, R. Deposit date: 2007-09-13 Release date: 2007-11-20 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature, 450, 2007
1DEN	PROTEINASE INHIBITOR HOMOLOGUES AS POTASSIUM CHANNEL BLOCKERS Descriptor: DENDROTOXIN I Authors: Lancelin, J.-M, Foray, M.-F. Deposit date: 1994-03-07 Release date: 1994-05-31 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Proteinase inhibitor homologues as potassium channel blockers. Nat.Struct.Biol., 1, 1994
1DEM	PROTEINASE INHIBITOR HOMOLOGUES AS POTASSIUM CHANNEL BLOCKERS Descriptor: DENDROTOXIN I Authors: Lancelin, J.-M, Foray, M.-F. Deposit date: 1994-03-07 Release date: 1994-05-31 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Proteinase inhibitor homologues as potassium channel blockers. Nat.Struct.Biol., 1, 1994
1QUZ	Solution structure of the potassium channel scorpion toxin HSTX1 Descriptor: HSTX1 TOXIN Authors: Savarin, P, Romi-Lebrun, R, Zinn-Justin, S, Lebrun, B, Nakajima, T, Gilquin, B, Menez, A. Deposit date: 1999-07-05 Release date: 2000-07-07 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Structural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: solution structure of the potassium channel inhibitor HsTX1. Protein Sci., 8, 1999
6D42	Crystal structure of the KCa3.1 C-terminal four-helix bundle (with copper) Descriptor: COPPER (II) ION, Intermediate conductance calcium-activated potassium channel protein 4 Authors: Hubbard, S.R, Ji, T. Deposit date: 2018-04-17 Release date: 2018-07-11 Last modified: 2019-12-18 Method: X-RAY DIFFRACTION (1.75013649 Å) Cite: Crystal structure of the C-terminal four-helix bundle of the potassium channel KCa3.1. PLoS ONE, 13, 2018
7SQW	Structure of the KcsA-W67F mutant with the activation gate in the closed conformation Descriptor: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Fragment, KcsA potassium channel, ... Authors: Cuello, L.G, Labro, A.J. Deposit date: 2021-11-07 Release date: 2022-10-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.21 Å) Cite: The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels. Sci Adv, 8, 2022
4LP8	A Novel Open-State Crystal Structure of the Prokaryotic Inward Rectifier KirBac3.1 Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Inward rectifier potassium channel Kirbac3.1, ... Authors: Zubcevic, L, Bavro, V.N, Muniz, J.R.C, Schmidt, M.R, Wang, S, De Zorzi, R, Venien-Bryan, C, Sansom, M.S.P, Nichols, C.G, Tucker, S.J. Deposit date: 2013-07-15 Release date: 2013-11-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.46 Å) Cite: Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains. J.Biol.Chem., 289, 2014
1KCP	3D STRUCTURE OF K-CONOTOXIN PVIIA, A NOVEL POTASSIUM CHANNEL-BLOCKING TOXIN FROM CONE SNAILS, NMR, 22 STRUCTURES Descriptor: KAPPA-CONOTOXIN PVIIA Authors: Savarin, P, Guenneugues, M, Gilquin, B, Lamthanh, H, Gasparini, S, Zinn-Justin, S, Menez, A. Deposit date: 1998-01-27 Release date: 1998-10-14 Last modified: 2017-11-29 Method: SOLUTION NMR Cite: Three-dimensional structure of kappa-conotoxin PVIIA, a novel potassium channel-blocking toxin from cone snails. Biochemistry, 37, 1998
1EMX	SOLUTION STRUCTURE OF HPTX2, A TOXIN FROM HETEROPODA VENATORIA SPIDER VENOM THAT BLOCKS KV4.2 POTASSIUM CHANNEL Descriptor: HETEROPODATOXIN 2 Authors: Bernard, C, Legros, C, Ferrat, G, Bishoff, U, Marquardt, A, Pongs, O, Darbon, H. Deposit date: 2000-03-20 Release date: 2001-01-24 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Solution structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel. Protein Sci., 9, 2000
1WQC	An unusual fold for potassium channel blockers : NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis Descriptor: OmTx1 Authors: Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. Deposit date: 2004-09-27 Release date: 2005-01-18 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis Biochem.J., 388, 2005
6V36	K2P2.1(TREK-1)I110D apo channel structure Descriptor: CADMIUM ION, N-OCTANE, POTASSIUM ION, ... Authors: Pope, L, Lolicato, M, Minor, D.L. Deposit date: 2019-11-25 Release date: 2020-02-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism. Cell Chem Biol, 2020
6V37	K2P2.1(TREK-1)I110D:RuR:ML335 bound channel structure Descriptor: CADMIUM ION, DODECANE, HEXANE, ... Authors: Pope, L, Lolicato, M, Minor, D.L. Deposit date: 2019-11-25 Release date: 2020-02-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism. Cell Chem Biol, 2020
6V3I	K2P2.1(TREK-1)I110D:RuR bound channel structure Descriptor: CADMIUM ION, DODECANE, HEXANE, ... Authors: Pope, L, Lolicato, M, Minor, D.L. Deposit date: 2019-11-25 Release date: 2020-02-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism. Cell Chem Biol, 2020
6V3C	K2P2.1(TREK-1)I110D:Ru360 bound channel structure Descriptor: CADMIUM ION, HEXANE, N-OCTANE, ... Authors: Pope, L, Lolicato, M, Minor, D.L. Deposit date: 2019-11-25 Release date: 2020-02-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.51 Å) Cite: Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism. Cell Chem Biol, 2020
1HP9	kappa-Hefutoxins: a novel Class of Potassium Channel Toxins from Scorpion venom Descriptor: kappa-hefutoxin 1 Authors: Srinivasan, K.N, Sivaraja, V, Huys, I, Sasaki, T, Cheng, B, Kumar, T.K.S, Sato, K, Tytgat, J, Yu, C, Brian Chia, C.S, Ranganathan, S, Bowie, J.H, Kini, R.M, Gopalakrishnakone, P. Deposit date: 2000-12-12 Release date: 2002-08-28 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity. J.Biol.Chem., 277, 2002
1WQE	An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis Descriptor: OmTx3 Authors: Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. Deposit date: 2004-09-28 Release date: 2005-01-18 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis Biochem.J., 388, 2005
1VP6	M.loti ion channel cylic nucleotide binding domain Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BROMIDE ION, Cyclic-nucleotide binding domain of mesorhizobium loti CNG potassium channel Authors: Clayton, G.M, Silverman, W.R, Heginbotham, L, Morais-Cabral, J.H. Deposit date: 2004-10-14 Release date: 2004-10-26 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell(Cambridge,Mass.), 119, 2004

<12345678910111213141516>