PDB: 5591 resultsInfo pagesStatus searchChemie searchBIRD

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7OT7	sTIM11noCys-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 2) Descriptor: sTIM11noCys-SB Authors: Romero-Romero, S, Kordes, S, Hocker, B. Deposit date: 2021-06-09 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.51 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7NFJ	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L28Y. Descriptor: CC-Type2-(LaId)4-L28Y Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFL	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24N. Descriptor: CC-Type2-(LaId)4-I24N Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.44 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFO	A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17C. Descriptor: CC-Type2-(LaId)4-I17C Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFF	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24A. Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CC-Type2-(LaId)4-I24A, GLYCEROL Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFI	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L7Y. Descriptor: CC-Type2-(LaId)4-L7Y Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFM	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L21K. Descriptor: CC-Type2-(LaId)4-L21K Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFP	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17K Descriptor: CC-Type2-(LaId)4-I17K, GLYCEROL Authors: Burton, A.J, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFK	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24S. Descriptor: CC-Type2-(LaId)4-I24S, ISOPROPYL ALCOHOL Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFG	A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L14A. Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, CC-Type2-(LaId)4-L14A Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.09 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFH	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(MaId)4. Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CC-Type2-(MaId)4 Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFN	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L21N-I24N. Descriptor: CC-Type2-(LaId)4-L21N-I24N, HEXANE-1,6-DIOL Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
5TX8	Solution structure of the de novo mini protein gHH_44 Descriptor: HH2 Authors: Buchko, G.W, Bahl, C.D, Baker, D. Deposit date: 2016-11-15 Release date: 2017-09-27 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides. Protein Sci., 27, 2018
1IVL	THE DE NOVO DESIGN OF AN ANTIBODY COMBINING SITE: CRYSTALLOGRAPHIC ANALYSIS OF THE VL DOMAIN CONFIRMS THE STRUCTURAL MODEL Descriptor: IGG-KAPPA M29B FV (LIGHT CHAIN), ISOPROPYL ALCOHOL Authors: Essen, L.-O, Skerra, A. Deposit date: 1994-05-04 Release date: 1994-08-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.17 Å) Cite: The de novo design of an antibody combining site. Crystallographic analysis of the VL domain confirms the structural model. J.Mol.Biol., 238, 1994
4DZN	A de novo designed Coiled Coil CC-pIL Descriptor: COILED-COIL PEPTIDE CC-PIL Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.59 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
4KYZ	Three-dimensional structure of triclinic form of de novo design insertion domain, Northeast Structural Genomics Consortium (NESG) Target OR327 Descriptor: Designed protein OR327 Authors: Kuzin, A, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Gleixner, J, Baker, D, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) Deposit date: 2013-05-29 Release date: 2013-07-24 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.492 Å) Cite: Precise assembly of complex beta sheet topologies from de novo designed building blocks. Elife, 4, 2015
4DZM	A de novo designed Coiled Coil CC-Di Descriptor: COILED-COIL PEPTIDE CC-DI Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.94 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
1C3C	T. MARITIMA ADENYLOSUCCINATE LYASE Descriptor: PROTEIN (ADENYLOSUCCINATE LYASE) Authors: Toth, E.A, Yeates, T.O. Deposit date: 1999-07-27 Release date: 2000-02-09 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway. Structure Fold.Des., 8, 2000
1C3U	T. MARITIMA ADENYLOSUCCINATE LYASE Descriptor: ADENYLOSUCCINATE LYASE, SULFATE ION Authors: Toth, E.A, Yeates, T.O. Deposit date: 1999-07-28 Release date: 2000-03-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway. Structure Fold.Des., 8, 2000
3B83	Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. Descriptor: TEN-D3 Authors: Hu, X, Ke, H, Kuhlman, B. Deposit date: 2007-10-31 Release date: 2008-11-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. Structure, 16, 2008
5EZE	A de novo designed heptameric coiled coil CC-Hept-I18betaMeCys-L22H-I25E Descriptor: CC-Hept-bMeCys-His-Glu, GLYCEROL Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZ9	A de novo designed heptameric coiled coil CC-Hept-I-H-I Descriptor: CC-Hept-L22H, HEXANE-1,6-DIOL Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5F2Y	A de novo designed heptameric coiled coil CC-Hept-homoCys-H-E Descriptor: CC-Hept-hCys-H-E Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-12-02 Release date: 2016-07-06 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZ8	A de novo designed heptameric coiled coil CC-Hept-I-C-I Descriptor: CC-Hept-I-C-I Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
6LLQ	Solution NMR structure of de novo Rossmann2x2 fold with most of the core mutated to valine, R2x2_VAL88 Descriptor: VAL88 Authors: Kobayashi, N, Sugiki, T, Fujiwara, T, Koga, R, Yamamoto, M, Kosugi, T, Koga, N. Deposit date: 2019-12-23 Release date: 2020-12-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Robust folding of a de novo designed ideal protein even with most of the core mutated to valine. Proc.Natl.Acad.Sci.USA, 117, 2020

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