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5NZU
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BU of 5nzu by Molmil
The structure of the COPI coat linkage II
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (15 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZS
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BU of 5nzs by Molmil
The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor
Descriptor: ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZT
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BU of 5nzt by Molmil
The structure of the COPI coat linkage I
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (17 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZV
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BU of 5nzv by Molmil
The structure of the COPI coat linkage IV
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (17.299999 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
6YET
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BU of 6yet by Molmil
Second EH domain of AtEH1/Pan1
Descriptor: CALCIUM ION, Calcium-binding EF hand family protein
Authors:Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K.
Deposit date:2020-03-25
Release date:2021-03-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Nat Commun, 12, 2021
6YEU
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BU of 6yeu by Molmil
Second EH domain of AtEH1/Pan1
Descriptor: CALCIUM ION, Calcium-binding EF hand family protein
Authors:Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K.
Deposit date:2020-03-25
Release date:2021-03-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Nat Commun, 12, 2021
3TW8
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BU of 3tw8 by Molmil
GEF domain of DENND 1B in complex with Rab GTPase Rab35
Descriptor: DENN domain-containing protein 1B, Ras-related protein Rab-35
Authors:Wu, X.D, Kummel, D, Reinisch, K.M.
Deposit date:2011-09-21
Release date:2011-11-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate.
Proc.Natl.Acad.Sci.USA, 108, 2011
8WU1
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BU of 8wu1 by Molmil
Cryo-EM structure of CB1-beta-arrestin1 complex
Descriptor: Beta-arrestin-1, Cannabinoid receptor 1,Vasopressin V2 receptor, Fab30 heavy chain, ...
Authors:Liao, Y, Zhang, H, Shen, Q, Cai, C.
Deposit date:2023-10-19
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of CB1-beta-arrestin1 complex
to be published
8W41
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BU of 8w41 by Molmil
Cryo-EM structure of Myosin VI in the autoinhibited state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
Authors:Niu, F, Wei, Z.
Deposit date:2023-08-23
Release date:2024-02-21
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Autoinhibition and activation of myosin VI revealed by its cryo-EM structure.
Nat Commun, 15, 2024
5C7Z
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BU of 5c7z by Molmil
AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
Descriptor: AP-2 complex subunit mu, Integrin alpha-4
Authors:Owen, D.J, Evans, P.R, Wilson, T.A.
Deposit date:2015-06-25
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide
To Be Published
4IKN
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BU of 4ikn by Molmil
Crystal structure of adaptor protein complex 3 (AP-3) mu3A subunit C-terminal domain, in complex with a sorting peptide from TGN38
Descriptor: AP-3 complex subunit mu-1, Trans-Golgi network integral membrane protein TGN38
Authors:Mardones, G.A, Kloer, D.P, Burgos, P.V, Bonifacino, J.S, Hurley, J.H.
Deposit date:2012-12-26
Release date:2013-02-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Structural basis for the recognition of tyrosine-based sorting signals by the mu 3A subunit of the AP-3 adaptor complex.
J.Biol.Chem., 288, 2013
8JRU
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BU of 8jru by Molmil
Cryo-EM structure of the glucagon receptor bound to beta-arrestin 1 in ligand-free state
Descriptor: Beta-arrestin 1 and single-chain fragment variable 30 (scFv30), HA signal peptide,HPC4 purification tag,Glucagon receptor,C-terminal tail of Vasopressin V2 receptor, Nanobody 32, ...
Authors:Chen, K, Zhang, C, Lin, S, Zhao, Q, Wu, B.
Deposit date:2023-06-17
Release date:2023-08-16
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tail engagement of arrestin at the glucagon receptor.
Nature, 620, 2023
6NI2
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BU of 6ni2 by Molmil
Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Descriptor: Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ...
Authors:Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J.
Deposit date:2018-12-26
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex.
Nat.Struct.Mol.Biol., 26, 2019
3ZY7
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BU of 3zy7 by Molmil
Crystal structure of computationally redesigned gamma-adaptin appendage domain forming a symmetric homodimer
Descriptor: AP-1 COMPLEX SUBUNIT GAMMA-1, DI(HYDROXYETHYL)ETHER, ISOPROPYL ALCOHOL
Authors:Stranges, P.B, Machius, M, Miley, M.J, Tripathy, A, Kuhlman, B.
Deposit date:2011-08-17
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Computational Design of a Symmetric Homodimer Using Beta-Strand Assembly.
Proc.Natl.Acad.Sci.USA, 108, 2011
2VJ0
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BU of 2vj0 by Molmil
Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, in complex with an FXDNF peptide from amphiphysin1 and a WVXF peptide from synaptojanin P170
Descriptor: AMPHIPHYSIN, AP-2 COMPLEX SUBUNIT ALPHA-2, BENZAMIDINE, ...
Authors:Ford, M.G.J, Praefcke, G.J.K, McMahon, H.T.
Deposit date:2007-12-06
Release date:2007-12-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Solitary and Repetitive Binding Motifs for the Ap2 Complex {Alpha}-Appendage in Amphiphysin and Other Accessory Proteins.
J.Biol.Chem., 283, 2008
7DFB
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BU of 7dfb by Molmil
Crystal of Arrestin2-V2Rpp-6-7-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DF9
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BU of 7df9 by Molmil
Crystal of Arrestin2-V2Rpp-1-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DFA
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BU of 7dfa by Molmil
Crystal of Arrestin2-V2Rpp-4-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7DFC
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BU of 7dfc by Molmil
Crystal of Arrestin2-V2Rpp-3-Fab30 complex
Descriptor: Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ...
Authors:Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L.
Deposit date:2020-11-06
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2.
Nat Commun, 12, 2021
7P3Y
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BU of 7p3y by Molmil
Homology model of the full-length AP-3 complex in an intermediate open conformation
Descriptor: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ...
Authors:Schubert, E, Raunser, S.
Deposit date:2021-07-09
Release date:2021-09-29
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J.Biol.Chem., 297, 2021
7P3Z
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BU of 7p3z by Molmil
Homology model of the full-length AP-3 complex in a stretched open conformation
Descriptor: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ...
Authors:Schubert, E, Raunser, S.
Deposit date:2021-07-09
Release date:2021-09-29
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (10.5 Å)
Cite:Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J.Biol.Chem., 297, 2021
7P3X
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BU of 7p3x by Molmil
Homology model of the full-length AP-3 complex in a compact open conformation
Descriptor: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ...
Authors:Schubert, E, Raunser, S.
Deposit date:2021-07-09
Release date:2021-09-29
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J.Biol.Chem., 297, 2021
8I0N
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BU of 8i0n by Molmil
Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C5a anaphylatoxin chemotactic receptor 1, C5aR1 (Local refine)
Descriptor: Beta-arrestin-1, C5a anaphylatoxin chemotactic receptor 1, Fab30 heavy chain, ...
Authors:Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K.
Deposit date:2023-01-11
Release date:2023-05-17
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structure of beta-arrestin in complex with a phosphopeptide
Mol.Cell, 2023
8I0Q
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BU of 8i0q by Molmil
Structure of beta-arrestin1 in complex with a phosphopeptide corresponding to the human C-X-C chemokine receptor type 4, CXCR4 (Local refine)
Descriptor: Beta-arrestin-1, C-X-C chemokine receptor type 4, Fab30 Heavy Chain, ...
Authors:Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K.
Deposit date:2023-01-11
Release date:2023-05-17
Method:ELECTRON MICROSCOPY (4.45 Å)
Cite:Structure of beta-arrestin in complex with a phosphopeptide
Mol.Cell, 2023
1G4R
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BU of 1g4r by Molmil
CRYSTAL STRUCTURE OF BOVINE BETA-ARRESTIN 1
Descriptor: BETA-ARRESTIN 1
Authors:Schubert, C, Han, M.
Deposit date:2000-10-27
Release date:2001-10-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane Translocation.
Structure, 9, 2001

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