3ZY7

Crystal structure of computationally redesigned gamma-adaptin appendage domain forming a symmetric homodimer

Summary for 3ZY7

Related2A7B 1GYU 1GYW 1W63 1GYV
DescriptorAP-1 COMPLEX SUBUNIT GAMMA-1, ISOPROPYL ALCOHOL, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
Functional Keywordsendocytosis, protein design, computational design
Biological sourceMUS MUSCULUS (HOUSE MOUSE)
Cellular locationGolgi apparatus P22892
Total number of polymer chains2
Total molecular weight27607.3
Authors
Stranges, P.B.,Machius, M.,Miley, M.J.,Tripathy, A.,Kuhlman, B. (deposition date: 2011-08-17, release date: 2011-12-28, Last modification date: 2012-01-11)
Primary citation
Stranges, P.B.,Machius, M.,Miley, M.J.,Tripathy, A.,Kuhlman, B.
Computational Design of a Symmetric Homodimer Using Beta-Strand Assembly.
Proc.Natl.Acad.Sci.USA, 108:20562-, 2011
PubMed: 22143762 (PDB entries with the same primary citation)
DOI: 10.1073/PNAS.1115124108
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.09 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.18611003.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution