4CPH
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![BU of 4cph by Molmil](/molmil-images/mine/4cph) | trans-divalent streptavidin with love-hate ligand 4 | Descriptor: | 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N'-{2,6-bis[4-(morpholine-4- sulfonyl)phenyl]phenyl}pentanehydrazide, STREPTAVIDIN | Authors: | Fairhead, M, Shen, D, Chan, L.K.M, Lowe, E.D, Donohoe, T.J, Howarth, M. | Deposit date: | 2014-02-06 | Release date: | 2014-08-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction. Bioorg.Med.Chem., 22, 2014
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4CPI
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![BU of 4cpi by Molmil](/molmil-images/mine/4cpi) | streptavidin A86D mutant with love-hate ligand 4 | Descriptor: | 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N'-{2,6-bis[4-(morpholine-4- sulfonyl)phenyl]phenyl}pentanehydrazide, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Fairhead, M, Shen, D, Chan, L.K.M, Lowe, E.D, Donohoe, T.J, Howarth, M. | Deposit date: | 2014-02-06 | Release date: | 2014-08-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction. Bioorg.Med.Chem., 22, 2014
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4CPF
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![BU of 4cpf by Molmil](/molmil-images/mine/4cpf) | Wild-type streptavidin in complex with love-hate ligand 3 (LH3) | Descriptor: | STREPTAVIDIN, methyl 4-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H- thieno[3,4-d]imidazolidin-4-yl]pentanehydrazido}-3- [4-(methoxycarbonyl)phenyl]phenyl)benzoate | Authors: | Fairhead, M, Shen, D, Chan, L.K.M, Lowe, E.D, Donohoe, T.J, Howarth, M. | Deposit date: | 2014-02-06 | Release date: | 2014-08-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction. Bioorg.Med.Chem., 22, 2014
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4CPE
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![BU of 4cpe by Molmil](/molmil-images/mine/4cpe) | Wild-type streptavidin in complex with love-hate ligand 1 (LH1) | Descriptor: | (3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4- d]imidazolidin-4-yl]-N-{2-[(2,6- diphenylphenyl)formamido]ethyl}pentanamide, STREPTAVIDIN | Authors: | Fairhead, M, Shen, D, Chan, L.K.M, Lowe, E.D, Donohoe, T.J, Howarth, M. | Deposit date: | 2014-02-06 | Release date: | 2014-08-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | Love-Hate Ligands for High Resolution Analysis of Strain in Ultra-Stable Protein/Small Molecule Interaction. Bioorg.Med.Chem., 22, 2014
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4BX7
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![BU of 4bx7 by Molmil](/molmil-images/mine/4bx7) | trans-divalent streptavidin bound to biotin-4-fluorescein | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, STREPTAVIDIN, biotin-4-fluorescein | Authors: | Fairhead, M, Krndija, D, Lowe, E.D, Howarth, M. | Deposit date: | 2013-07-08 | Release date: | 2013-09-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Plug-and-Play Pairing Via Defined Divalent Streptavidins. J.Mol.Biol., 426, 2014
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4DNE
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![BU of 4dne by Molmil](/molmil-images/mine/4dne) | Crystal structure of a triple-mutant of streptavidin in complex with desthiobiotin | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, SULFATE ION, Streptavidin | Authors: | Panwar, P, Deniaud, A, Pebay-Peyroula, E. | Deposit date: | 2012-02-08 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Contamination from an affinity column: an encounter with a new villain in the world of membrane-protein crystallization. Acta Crystallogr.,Sect.D, 68, 2012
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4BX5
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![BU of 4bx5 by Molmil](/molmil-images/mine/4bx5) | cis-divalent streptavidin | Descriptor: | 1,2-ETHANEDIOL, STREPTAVIDIN, TETRAETHYLENE GLYCOL | Authors: | Fairhead, M, Krndija, D, Lowe, E.D, Howarth, M. | Deposit date: | 2013-07-08 | Release date: | 2013-09-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.431 Å) | Cite: | Plug-and-Play Pairing Via Defined Divalent Streptavidins. J.Mol.Biol., 426, 2014
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4BCS
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![BU of 4bcs by Molmil](/molmil-images/mine/4bcs) | Crystal structure of an avidin mutant | Descriptor: | ACETATE ION, BIOTIN, CHIMERIC AVIDIN, ... | Authors: | Airenne, T.T, Niederhauser, B, Hytonen, V.P, Kulomaa, M.S, Johnson, M.S. | Deposit date: | 2012-10-03 | Release date: | 2013-10-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Novel Chimeric Avidin with Increased Thermal Stability Using DNA Shuffling. Plos One, 9, 2014
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4BX6
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![BU of 4bx6 by Molmil](/molmil-images/mine/4bx6) | trans-divalent streptavidin | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, STREPTAVIDIN | Authors: | Fairhead, M, Krndija, D, Lowe, E.D, Howarth, M. | Deposit date: | 2013-07-08 | Release date: | 2013-09-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.595 Å) | Cite: | Plug-and-Play Pairing Via Defined Divalent Streptavidins. J.Mol.Biol., 426, 2014
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4EKV
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![BU of 4ekv by Molmil](/molmil-images/mine/4ekv) | Streptavidin 8-aa-loop H127C mutein with reversible biotin binding | Descriptor: | BIOTIN, CHLORIDE ION, Streptavidin | Authors: | Barrette-Ng, I.H, Honetschlaeger, C, Wong, S.L, Ng, K.K.S. | Deposit date: | 2012-04-09 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Development of a tetrameric streptavidin mutein with reversible biotin binding capability: engineering a mobile loop as an exit door for biotin. Plos One, 7, 2012
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3PK2
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![BU of 3pk2 by Molmil](/molmil-images/mine/3pk2) | Artificial Transfer Hydrogenases for the Enantioselective Reduction of Cyclic Imines | Descriptor: | IRIDIUM (III) ION, Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III) | Authors: | Schirmer, T, Heinisch, T. | Deposit date: | 2010-11-11 | Release date: | 2011-04-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Artificial transfer hydrogenases for the enantioselective reduction of cyclic imines. Angew.Chem.Int.Ed.Engl., 50, 2011
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3RDO
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![BU of 3rdo by Molmil](/molmil-images/mine/3rdo) | Crystal structure of R7-2 streptavidin complexed with biotin | Descriptor: | BIOTIN, GLYCEROL, NICKEL (II) ION, ... | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | Deposit date: | 2011-04-01 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.404 Å) | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci., 20, 2011
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3RE5
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![BU of 3re5 by Molmil](/molmil-images/mine/3re5) | Crystal structure of R4-6 streptavidin | Descriptor: | GLYCEROL, PENTAETHYLENE GLYCOL, Streptavidin | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | Deposit date: | 2011-04-02 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci., 20, 2011
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3RDS
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![BU of 3rds by Molmil](/molmil-images/mine/3rds) | Crystal structure of the refolded R7-2 streptavidin | Descriptor: | PENTAETHYLENE GLYCOL, Streptavidin | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | Deposit date: | 2011-04-01 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci., 20, 2011
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3RDM
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![BU of 3rdm by Molmil](/molmil-images/mine/3rdm) | Crystal structure of R7-2 streptavidin complexed with biotin/PEG | Descriptor: | BIOTIN, PENTAETHYLENE GLYCOL, Streptavidin | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | Deposit date: | 2011-04-01 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci., 20, 2011
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3RDU
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![BU of 3rdu by Molmil](/molmil-images/mine/3rdu) | Crystal structure of R7-2 streptavidin complexed with PEG | Descriptor: | GLYCEROL, PENTAETHYLENE GLYCOL, Streptavidin | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | Deposit date: | 2011-04-01 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci., 20, 2011
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3RY1
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![BU of 3ry1 by Molmil](/molmil-images/mine/3ry1) | Wild-type core streptavidin at atomic resolution | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Streptavidin | Authors: | Stenkamp, R.E, Wang, Z, Le Trong, I, Stayton, P.S, Lybrand, T.P. | Deposit date: | 2011-05-10 | Release date: | 2011-08-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Streptavidin and its biotin complex at atomic resolution. Acta Crystallogr.,Sect.D, 67, 2011
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3RDQ
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![BU of 3rdq by Molmil](/molmil-images/mine/3rdq) | Crystal structure of R7-2 streptavidin complexed with desthiobiotin | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, GLYCEROL, NICKEL (II) ION, ... | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | Deposit date: | 2011-04-01 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci., 20, 2011
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3RY2
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![BU of 3ry2 by Molmil](/molmil-images/mine/3ry2) | Wild-type core streptavidin-biotin complex at atomic resolution | Descriptor: | BIOTIN, GLYCEROL, Streptavidin | Authors: | Stenkamp, R.E, Le Trong, I, Stayton, P.S, Lybrand, T.P. | Deposit date: | 2011-05-10 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Streptavidin and its biotin complex at atomic resolution. Acta Crystallogr.,Sect.D, 67, 2011
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3RE6
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![BU of 3re6 by Molmil](/molmil-images/mine/3re6) | Crystal structure of R4-6 streptavidin | Descriptor: | GLYCEROL, Streptavidin | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | Deposit date: | 2011-04-02 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.823 Å) | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci., 20, 2011
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3RDX
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![BU of 3rdx by Molmil](/molmil-images/mine/3rdx) | Crystal structure of ligand-free R7-2 streptavidin | Descriptor: | GLYCEROL, Streptavidin | Authors: | Malashkevich, V.N, Magalhaes, M, Czecster, C.M, Guan, R, Levy, M, Almo, S.C. | Deposit date: | 2011-04-02 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Evolved streptavidin mutants reveal key role of loop residue in high-affinity binding. Protein Sci., 20, 2011
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3SZJ
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![BU of 3szj by Molmil](/molmil-images/mine/3szj) | Structure of the shwanavidin-biotin complex | Descriptor: | ACETIC ACID, Avidin/streptavidin, BIOTIN, ... | Authors: | Livnah, O, Meir, A. | Deposit date: | 2011-07-19 | Release date: | 2012-04-11 | Last modified: | 2012-06-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural Adaptation of a Thermostable Biotin-binding Protein in a Psychrophilic Environment. J.Biol.Chem., 287, 2012
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3T2W
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![BU of 3t2w by Molmil](/molmil-images/mine/3t2w) | |
3SZI
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![BU of 3szi by Molmil](/molmil-images/mine/3szi) | Structure of apo shwanavidin (P21 form) | Descriptor: | Avidin/streptavidin, FORMIC ACID | Authors: | Livnah, O, Meir, A. | Deposit date: | 2011-07-19 | Release date: | 2012-04-25 | Last modified: | 2012-06-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Adaptation of a Thermostable Biotin-binding Protein in a Psychrophilic Environment. J.Biol.Chem., 287, 2012
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6UIY
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![BU of 6uiy by Molmil](/molmil-images/mine/6uiy) | Artificial Iron Proteins: Modelling the Active Sites in Non-Heme Dioxygenases | Descriptor: | ACETATE ION, Streptavidin, {5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(2-{[(pyridin-2-yl)methyl][(pyridin-2-yl-kappaN)methyl]amino-kappaN}ethyl)pentanamide}iron(2+) | Authors: | Miller, K.R, Paretsky, J.D, Follmer, A.H, Heinisch, T, Mittra, K, Gul, S, Kim, I.-S, Fuller, F.D, Batyuk, A, Sutherlin, K.D, Brewster, A.S, Bhowmick, A, Sauter, N.K, Kern, J, Yano, J, Green, M.T, Ward, T.R, Borovik, A.S. | Deposit date: | 2019-10-01 | Release date: | 2020-05-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Artificial Iron Proteins: Modeling the Active Sites in Non-Heme Dioxygenases. Inorg.Chem., 59, 2020
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