PDB Search results for query - Protein Data Bank Japan

PDB: 594 results Info pages Status search Chemie search BIRD

Crystal structure of SOCS3 in complex with gp130(pTyr757) phosphopeptide.
Descriptor:	Interleukin-6 receptor beta chain, Suppressor of cytokine signaling 3
Authors:	Bergamin, E, Wu, J, Hubbard, S.R.
Deposit date:	2006-07-11
Release date:	2006-08-15
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3. Structure, 14, 2006

2C0I

Src family kinase Hck with bound inhibitor A-420983
Descriptor:	CALCIUM ION, N-(4-{4-AMINO-1-[4-(4-METHYLPIPERAZIN-1-YL)-TRANS-CYCLOHEXYL]-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE, TYROSINE-PROTEIN KINASE HCK
Authors:	Borhani, D.W, Burchat, A, Calderwood, D.J, Hirst, G.C, Li, B, Loew, A.
Deposit date:	2005-09-03
Release date:	2006-09-20
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Discovery of A-770041, a Src-Family Selective Orally Active Lck Inhibitor that Prevents Organ Allograft Rejection. Bioorg.Med.Chem.Lett., 16, 2006

2C0O

Src family kinase Hck with bound inhibitor A-770041
Descriptor:	CALCIUM ION, N-(4-{1-[4-(4-ACETYLPIPERAZIN-1-YL)-TRANS-CYCLOHEXYL]-4-AMINO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE, TYROSINE-PROTEIN KINASE HCK
Authors:	Borhani, D.W, Burchat, A, Calderwood, D.J, Hirst, G.C, Li, B, Loew, A.
Deposit date:	2005-09-06
Release date:	2006-09-20
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2.85 Å)
Cite:	Discovery of A-770041, a Src-Family Selective Orally Active Lck Inhibitor that Prevents Organ Allograft Rejection. Bioorg.Med.Chem.Lett., 16, 2006

2C0T

Src family kinase Hck with bound inhibitor A-641359
Descriptor:	CALCIUM ION, N-(4-{4-AMINO-1-[1-(TETRAHYDRO-2H-PYRAN-4-YL)PIPERIDIN-4-YL]-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE, TYROSINE-PROTEIN KINASE HCK
Authors:	Borhani, D.W, Burchat, A, Calderwood, D.J, Hirst, G.C, Li, B, Loew, A.
Deposit date:	2005-09-07
Release date:	2006-09-20
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Discovery of A-770041, a Src-Family Selective Orally Active Lck Inhibitor that Prevents Organ Allograft Rejection. Bioorg.Med.Chem.Lett., 16, 2006

2DCR

Fully automated solution structure determination of the Fes SH2 domain
Descriptor:	Proto-oncogene tyrosine-protein kinase Fes/Fps
Authors:	Lopez-Mendez, B, Guntert, P.
Deposit date:	2006-01-12
Release date:	2006-10-17
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Automated protein structure determination from NMR spectra J.AM.CHEM.SOC., 128, 2006

2DM0

Solution structure of the SH2 domain of human Tyrosine-protein kinase TXK
Descriptor:	Tyrosine-protein kinase TXK
Authors:	Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:	2006-04-20
Release date:	2006-10-20
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Solution structure of the SH2 domain of human Tyrosine-protein kinase TXK To be Published

2DLY

Solution structure of the SH2 domain of murine Fyn-related kinase
Descriptor:	Fyn-related kinase
Authors:	Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:	2006-04-20
Release date:	2006-10-20
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Solution structure of the SH2 domain of murine Fyn-related kinase To be Published

2GE9

Solution Structures of the SH2 domain of Bruton's Tyrosine Kinase
Descriptor:	Tyrosine-protein kinase BTK
Authors:	Cheng, J.-W, Huang, K.-C.
Deposit date:	2006-03-18
Release date:	2006-10-24
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase J.Biomol.Nmr, 36, 2006

2EYZ

CT10-Regulated Kinase isoform II
Descriptor:	v-crk sarcoma virus CT10 oncogene homolog isoform a
Authors:	Kobashigawa, Y, Tanaka, S, Inagaki, F.
Deposit date:	2005-11-10
Release date:	2006-11-10
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007

2EYV

SH2 domain of CT10-Regulated Kinase
Descriptor:	v-crk sarcoma virus CT10 oncogene homolog isoform a
Authors:	Kobashigawa, Y, Tanaka, S, Inagaki, F.
Deposit date:	2005-11-10
Release date:	2006-11-10
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007

2EYY

CT10-Regulated Kinase isoform I
Descriptor:	v-crk sarcoma virus CT10 oncogene homolog isoform a
Authors:	Kobashigawa, Y, Tanaka, S, Inagaki, F.
Deposit date:	2005-11-10
Release date:	2006-11-10
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007

2H8H

Src kinase in complex with a quinazoline inhibitor
Descriptor:	N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE, Proto-oncogene tyrosine-protein kinase Src
Authors:	Otterbein, L.R, Norman, R, Pauptit, R.A, Rowsell, S, Breed, J.
Deposit date:	2006-06-07
Release date:	2006-11-21
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. J.Med.Chem., 49, 2006

2OQ1

Tandem SH2 domains of ZAP-70 with 19-mer zeta1 peptide
Descriptor:	LEAD (II) ION, T-cell surface glycoprotein CD3 zeta chain, Tyrosine-protein kinase ZAP-70
Authors:	Hatada, M.H, Laird, E.R, Green, J, Morgenstern, J, Ram, M.K.
Deposit date:	2007-01-30
Release date:	2007-03-06
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Molecular basis for the interaction of ZAP-70 with the T-cell receptor Nature, 377, 1995

2DLZ

Solution structure of the SH2 domain of human protein vav-2
Descriptor:	Protein vav-2
Authors:	Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:	2006-04-20
Release date:	2007-04-03
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Solution structure of the SH2 domain of human protein vav-2 To be Published

2GSB

Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1
Descriptor:	Ras GTPase-activating protein 1
Authors:	Kurosaki, C, Suetake, T, Yoshida, M, Hayashi, F, Yokoyma, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:	2006-04-26
Release date:	2007-05-01
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1 To be Published

2DVJ

phosphorylated Crk-II
Descriptor:	V-crk sarcoma virus CT10 oncogene homolog, isoform a
Authors:	Kobashigawa, Y, Inagaki, F.
Deposit date:	2006-07-31
Release date:	2007-05-08
Last modified:	2022-03-09
Method:	SOLUTION NMR
Cite:	Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. Nat.Struct.Mol.Biol., 14, 2007

2OZO

Autoinhibited intact human ZAP-70
Descriptor:	MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tyrosine-protein kinase ZAP-70
Authors:	Deindl, S, Kadlecek, T.A, Brdicka, T, Cao, X, Weiss, A, Kuriyan, J.
Deposit date:	2007-02-26
Release date:	2007-05-22
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Structural Basis for the Inhibition of Tyrosine Kinase Activity of ZAP-70. Cell(Cambridge,Mass.), 129, 2007

2DX0

Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2
Descriptor:	Phospholipase C, gamma 2, SULFATE ION
Authors:	Handa, N, Takagi, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:	2006-08-22
Release date:	2007-09-04
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Crystal structure of the N-terminal SH2 domain of mouse phospholipase C-gamma 2 To be Published

2EKX

Solution structure of the human BMX SH2 domain
Descriptor:	Cytoplasmic tyrosine-protein kinase BMX
Authors:	Kasai, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:	2007-03-26
Release date:	2007-10-02
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Solution structure of the human BMX SH2 domain To be Published

2RD0

Structure of a human p110alpha/p85alpha complex
Descriptor:	Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:	Huang, C, Gabelli, S.B, Amzel, L.M.
Deposit date:	2007-09-20
Release date:	2007-12-25
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (3.05 Å)
Cite:	The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. Science, 318, 2007

2VIF

Crystal structure of SOCS6 SH2 domain in complex with a c-KIT phosphopeptide
Descriptor:	1,2-ETHANEDIOL, MAST/STEM CELL GROWTH FACTOR RECEPTOR, SUPPRESSOR OF CYTOKINE SIGNALLING 6
Authors:	Bullock, A, Pike, A.C.W, Savitsky, P, Keates, T, Pilka, E.S, von Delft, F, Edwards, A, Weigelt, J, Arrowsmith, C.H, Knapp, S.
Deposit date:	2007-11-30
Release date:	2007-12-25
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (1.45 Å)
Cite:	Structural Basis for C-Kit Inhibition by the Suppressor of Cytokine Signaling 6 (Socs6) Ubiquitin Ligase. J.Biol.Chem., 286, 2011

3BKB

Crystal structure of human Feline Sarcoma Viral Oncogene Homologue (v-FES)
Descriptor:	1,2-ETHANEDIOL, Proto-oncogene tyrosine-protein kinase Fes/Fps, STAUROSPORINE, ...
Authors:	Filippakopoulos, P, Salah, E, Fedorov, O, Cooper, C, Ugochukwu, E, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:	2007-12-06
Release date:	2007-12-25
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.78 Å)
Cite:	Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation Cell(Cambridge,Mass.), 134, 2008

2ECD

Solution structure of the human ABL2 SH2 domain
Descriptor:	Tyrosine-protein kinase ABL2
Authors:	Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:	2007-02-13
Release date:	2008-02-19
Last modified:	2024-05-29
Method:	SOLUTION NMR
Cite:	Solution structure of the human ABL2 SH2 domain To be Published

3CBL

Crystal structure of human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide
Descriptor:	Proto-oncogene tyrosine-protein kinase Fes/Fps, STAUROSPORINE, Synthetic peptide
Authors:	Filippakopoulos, P, Salah, E, Cooper, C, Picaud, S.S, Elkins, J.M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:	2008-02-22
Release date:	2008-03-04
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation Cell(Cambridge,Mass.), 134, 2008

3CD3

Crystal structure of phosphorylated human feline sarcoma viral oncogene homologue (v-FES) in complex with staurosporine and a consensus peptide
Descriptor:	CHLORIDE ION, Proto-oncogene tyrosine-protein kinase Fes/Fps, STAUROSPORINE, ...
Authors:	Filippakopoulos, P, Salah, E, Cooper, C, Picaud, S.S, Elkins, J.M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:	2008-02-26
Release date:	2008-03-25
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.98 Å)
Cite:	Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation Cell(Cambridge,Mass.), 134, 2008

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Total results:	594
Displayed results:	25
Sorted by:	Release date (from oldest)
Query:	PF00017