1CQ6
 
 | | ASPARTATE AMINOTRANSFERASE COMPLEX WITH C4-PYRIDOXAL-5P-PHOSPHATE | | Descriptor: | 2-[O-PHOSPHONOPYRIDOXYL]-AMINO- BUTYRIC ACID, ASPARTATE AMINOTRANSFERASE | | Authors: | Ishijima, J, Nakai, T, Kawaguchi, S, Hirotsu, K, Kuramitsu, S. | | Deposit date: | 1999-08-06 | | Release date: | 2000-12-20 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Free energy requirement for domain movement of an enzyme
J.Biol.Chem., 275, 2000
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3B8X
 | | Crystal structure of GDP-4-keto-6-deoxymannose-3-dehydratase (ColD) H188N mutant with bound GDP-perosamine | | Descriptor: | 1,2-ETHANEDIOL, Pyridoxamine 5-phosphate-dependent dehydrase, SODIUM ION, ... | | Authors: | Cook, P.D, Holden, H.M. | | Deposit date: | 2007-11-02 | | Release date: | 2007-11-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | GDP-4-Keto-6-deoxy-D-mannose 3-Dehydratase, Accommodating a Sugar Substrate in the Active Site.
J.Biol.Chem., 283, 2008
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3B75
 | | Crystal Structure of Glycated Human Haemoglobin | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Saraswathi, N.T, Syakhovich, V.E, Bokut, S.B, Moras, D, Ruff, M. | | Deposit date: | 2007-10-30 | | Release date: | 2008-10-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The effect of hemoglobin glycosylation on diabete linked oxidative stress
To be Published
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3B96
 | | Structural Basis for Substrate Fatty-Acyl Chain Specificity: Crystal Structure of Human Very-Long-Chain Acyl-CoA Dehydrogenase | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, TETRADECANOYL-COA, Very long-chain specific acyl-CoA dehydrogenase | | Authors: | McAndrew, R.P, Wang, Y, Mohsen, A.W, He, M, Vockley, J, Kim, J.J. | | Deposit date: | 2007-11-02 | | Release date: | 2008-02-12 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase.
J.Biol.Chem., 283, 2008
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2WXU
 | | Clostridium perfringens alpha-toxin strain NCTC8237 mutant T74I | | Descriptor: | CADMIUM ION, CALCIUM ION, PHOSPHOLIPASE C, ... | | Authors: | Vachieri, S.G, Naylor, C.E, Basak, A.K. | | Deposit date: | 2009-11-10 | | Release date: | 2009-11-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
Acta Crystallogr.,Sect.D, 66, 2010
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2X67
 | | The ternary complex of PrnB (the second enzyme in pyrrolnitrin biosynthesis pathway), tryptophan and cyanide | | Descriptor: | CYANIDE ION, PRNB, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Zhu, X, van pee, K.-H, Naismith, J.H. | | Deposit date: | 2010-02-15 | | Release date: | 2010-03-02 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | The Ternary Complex of Prnb (the Second Enzyme in Pyrrolnitrin Biosynthesis Pathway), Tryptophan and Cyanide Yields New Mechanistic Insights Into the Indolamine Dioxygenase Superfamily.
J.Biol.Chem., 285, 2010
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1D7V
 | | CRYSTAL STRUCTURE OF THE COMPLEX OF 2,2-DIALKYLGLYCINE DECARBOXYLASE WITH NMA | | Descriptor: | N-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-2-METHYLALANINE, POTASSIUM ION, PROTEIN (2,2-DIALKYLGLYCINE DECARBOXYLASE (PYRUVATE)), ... | | Authors: | Malashkevich, V.N, Toney, M.D, Strop, P, Keller, J, Jansonius, J.N. | | Deposit date: | 1999-10-19 | | Release date: | 1999-11-19 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of dialkylglycine decarboxylase inhibitor complexes.
J.Mol.Biol., 294, 1999
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2WTX
 | | Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase | | Descriptor: | 1,2-ETHANEDIOL, ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING], ... | | Authors: | Errey, J.C, Lee, S.S, Gibson, R.P, Martinez-Fleites, C, Barry, C.S, Jung, P.M.J, OSullivan, A, Davis, B.G, Davies, G.J. | | Deposit date: | 2009-09-25 | | Release date: | 2010-02-23 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanistic Insight Into Enzymatic Glycosyl Transfer with Retention of Configuration Through Analysis of Glycomimetic Inhibitors.
Angew.Chem.Int.Ed.Engl., 49, 2010
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2ZDO
 | | Crystal structure of IsdG-N7A in complex with hemin | | Descriptor: | Heme-degrading monooxygenase isdG, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Lee, W.C, Reniere, M.L, Skaar, E.P, Murphy, M.E.P. | | Deposit date: | 2007-11-27 | | Release date: | 2008-08-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Ruffling of Metalloporphyrins Bound to IsdG and IsdI, Two Heme-degrading Enzymes in Staphylococcus aureus
J.Biol.Chem., 283, 2008
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1CNI
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2WUE
 | | Crystal structure of S114A mutant of HsaD from Mycobacterium tuberculosis in complex with HOPODA | | Descriptor: | (3E,5R)-8-(2-CHLOROPHENYL)-5-METHYL-2,6-DIOXOOCT-3-ENOATE, 2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE BPHD, THIOCYANATE ION | | Authors: | Lack, N.A, Yam, K.C, Lowe, E.D, Horsman, G.P, Owen, R, Sim, E, Eltis, L.D. | | Deposit date: | 2009-10-02 | | Release date: | 2009-10-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Characterization of a carbon-carbon hydrolase from Mycobacterium tuberculosis involved in cholesterol metabolism.
J. Biol. Chem., 285, 2010
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1CGW
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1D6M
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1CI8
 | | ESTERASE ESTB FROM BURKHOLDERIA GLADIOLI: AN ESTERASE WITH (BETA)-LACTAMASE FOLD. | | Descriptor: | ISOPROPYL ALCOHOL, PROTEIN (CARBOXYLESTERASE) | | Authors: | Wagner, U.G, Petersen, E.I, Schwab, H, Kratky, C. | | Deposit date: | 1999-04-08 | | Release date: | 2001-12-12 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | EstB from Burkholderia gladioli: a novel esterase with a beta-lactamase fold reveals steric factors to discriminate between esterolytic and beta-lactam cleaving activity
Protein Sci., 11, 2002
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2ZGN
 | | crystal structure of recombinant Agrocybe aegerita lectin, rAAL, complex with galactose | | Descriptor: | Anti-tumor lectin, beta-D-galactopyranose | | Authors: | Yang, N, Li, D.F, Wang, D.C. | | Deposit date: | 2008-01-23 | | Release date: | 2009-01-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita
J.Mol.Biol., 387, 2009
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2XAK
 | | Ribonucleotide reductase Y730NO2Y modified R1 subunit of E. coli | | Descriptor: | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA | | Authors: | Yokoyama, K, Uhlin, U, Stubbe, J. | | Deposit date: | 2010-03-31 | | Release date: | 2010-04-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase.
J.Am.Chem.Soc., 132, 2010
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2ZHM
 | | Crystal structure of human galectin-9 N-terminal CRD in complex with N-acetyllactosamine trimer (crystal 1) | | Descriptor: | (R)-1-PARA-NITRO-PHENYL-2-AZIDO-ETHANOL, Galectin-9, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Nagae, M, Nishi, N, Murata, T, Usui, T, Nakamura, T, Wakatsuki, S, Kato, R. | | Deposit date: | 2008-02-06 | | Release date: | 2008-12-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain.
Glycobiology, 19, 2009
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2WOM
 | | Crystal Structure of UK-453061 bound to HIV-1 Reverse Transcriptase (K103N). | | Descriptor: | 5-{[3,5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile, HIV-1 REVERSE TRANSCRIPTASE | | Authors: | Phillips, C, Irving, S.L, Knoechel, T, Ringrose, H. | | Deposit date: | 2009-07-27 | | Release date: | 2010-08-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1.
Antimicrob. Agents Chemother., 54, 2010
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2ZRS
 | | Crystal structure of Ca2+-bound form of des3-23ALG-2 | | Descriptor: | CALCIUM ION, Programmed cell death protein 6 | | Authors: | Suzuki, H, Kawasaki, M, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M. | | Deposit date: | 2008-09-01 | | Release date: | 2008-11-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystallization and X-ray diffraction analysis of N-terminally truncated human ALG-2
ACTA CRYSTALLOGR.,SECT.F, 64, 2008
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1CIR
 | | COMPLEX OF TWO FRAGMENTS OF CI2 [(1-40)(DOT)(41-64)] | | Descriptor: | CHYMOTRYPSIN INHIBITOR 2 | | Authors: | Davis, B.J, Fersht, A.R. | | Deposit date: | 1995-10-02 | | Release date: | 1996-01-29 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism
Structure Fold.Des., 1, 1996
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1D7R
 | | CRYSTAL STRUCTURE OF THE COMPLEX OF 2,2-DIALKYLGLYCINE DECARBOXYLASE WITH 5PA | | Descriptor: | N-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-Y-LMETHYL]-1-AMINO-CYCLOPROPANECARBOXYLIC ACID, POTASSIUM ION, PROTEIN (2,2-DIALKYLGLYCINE DECARBOXYLASE (PYRUVATE)), ... | | Authors: | Malashkevich, V.N, Toney, M.D, Strop, P, Keller, J, Jansonius, J.N. | | Deposit date: | 1999-10-19 | | Release date: | 1999-11-19 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of dialkylglycine decarboxylase inhibitor complexes.
J.Mol.Biol., 294, 1999
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2WYJ
 | | Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs | | Descriptor: | (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, FACTOR X LIGHT CHAIN | | Authors: | Kleanthous, S, Borthwick, A.D, Brown, D, Burns-Kurtis, C.L, Campbell, M, Chaudry, L, Chan, C, Clarte, M, Convery, M.A, Harling, J.D, Hortense, E, Irving, W.R, Irvine, S, Pateman, A.J, Patikis, A, Pinto, I.L, Pollard, D.R, Roethka, T.J, Senger, S, Shah, G.P, Stelman, G.J, Toomey, J.R, Watson, N.S, Whittaker, C, Zhou, P, Young, R.J. | | Deposit date: | 2009-11-16 | | Release date: | 2010-12-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Monoaryl P4 Motifs
Bioorg.Med.Chem.Lett., 20, 2010
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2WY6
 | | Clostridium perfringens alpha-toxin strain NCTC8237 mutant T74I | | Descriptor: | CADMIUM ION, CALCIUM ION, GLYCEROL, ... | | Authors: | Vachieri, S.G, Naylor, C.E, Basak, A.K. | | Deposit date: | 2009-11-12 | | Release date: | 2009-11-24 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
Acta Crystallogr.,Sect.D, 66, 2011
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2ZWL
 | | Human factor viia-tissue factor complexed with highly selective peptide inhibitor | | Descriptor: | 2-[[(2R)-1-[[(2S)-5-amino-1-[(4-carbamimidoylphenyl)methylamino]-1,5-dioxo-pentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]sulfamoyl]ethanoic acid, CALCIUM ION, Factor VII heavy chain, ... | | Authors: | Kadono, S, Sakamoto, A, Kikuchi, Y, Oh-Eda, M, Yabuta, N, Koga, T, Hattori, K, Shiraishi, T, Haramura, M, Sato, H, Ohta, M, Kozono, T. | | Deposit date: | 2008-12-16 | | Release date: | 2009-01-20 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Human factor viia-tissue factor complexed with highly selective peptide inhibitor
To be Published
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1CYE
 | | THREE DIMENSIONAL STRUCTURE OF CHEMOTACTIC CHE Y PROTEIN IN AQUEOUS SOLUTION BY NUCLEAR MAGNETIC RESONANCE METHODS | | Descriptor: | CHEY | | Authors: | Santoro, J, Bruix, M, Pascual, J, Lopez, E, Serrano, L, Rico, M. | | Deposit date: | 1994-10-21 | | Release date: | 1995-02-07 | | Last modified: | 2024-04-10 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional structure of chemotactic Che Y protein in aqueous solution by nuclear magnetic resonance methods.
J.Mol.Biol., 247, 1995
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