8QW2
| Human NDPK-C in complex with UDP and Mg2+ | Descriptor: | MAGNESIUM ION, Nucleoside diphosphate kinase 3, URIDINE-5'-DIPHOSPHATE | Authors: | Werten, S, Amjadi, R, Scheffzek, K. | Deposit date: | 2023-10-18 | Release date: | 2024-09-18 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes. Int J Mol Sci, 25, 2024
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8QW0
| Human NDPK-C in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase 3, SULFATE ION | Authors: | Werten, S, Amjadi, R, Scheffzek, K. | Deposit date: | 2023-10-18 | Release date: | 2024-09-18 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.175 Å) | Cite: | Mechanistic Insights into Substrate Recognition of Human Nucleoside Diphosphate Kinase C Based on Nucleotide-Induced Structural Changes. Int J Mol Sci, 25, 2024
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8QP6
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8R0C
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8QPQ
| C1 turret to capsid interface of full Haloferax tailed virus 1 adjacent to the portal-capsid interface. | Descriptor: | HK97 gp5-like major capsid protein, MAGNESIUM ION, Prokaryotic polysaccharide deacetylase, ... | Authors: | Zhang, D, Daum, B, Isupov, M.N, McLaren, M. | Deposit date: | 2023-10-02 | Release date: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | CryoEM structure of Haloferax tailed virus 1 To Be Published
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6SKO
| Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork - conformation 2 MCM CTD:ssDNA | Descriptor: | DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ... | Authors: | Yeeles, J, Baretic, D, Jenkyn-Bedford, M. | Deposit date: | 2019-08-16 | Release date: | 2020-05-06 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork. Mol.Cell, 78, 2020
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8QWE
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6SKN
| Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,8) | Descriptor: | Gag protein | Authors: | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | Deposit date: | 2019-08-16 | Release date: | 2020-08-26 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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8OHZ
| Yeast 20S proteasome in complex with a photoswitchable cepafungin derivative (transCep1) | Descriptor: | (2~{S},3~{R})-2-[2-[4-[2-(4-ethylphenyl)hydrazinyl]phenyl]ethanoylamino]-~{N}-[(5~{S},8~{S},10~{S})-5-methyl-10-oxidanyl-2,7-bis(oxidanylidene)-1,6-diazacyclododec-8-yl]-3-oxidanyl-butanamide, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Morstein, J, Amatuni, A, Schuster, A, Kuttenlochner, W, Ko, T, Groll, M, Adibekian, A, Renata, H, Trauner, D.H. | Deposit date: | 2023-03-21 | Release date: | 2023-12-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide. Angew.Chem.Int.Ed.Engl., 63, 2024
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8QBX
| Chimeric Adenovirus-derived dodecamer | Descriptor: | Penton protein | Authors: | Buzas, D, Borucu, U, Bufton, J, Kapadalakere, S.Y, Toelzer, C. | Deposit date: | 2023-08-25 | Release date: | 2023-12-27 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders. Structure, 32, 2024
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8Q7Y
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8QCF
| yeast cytoplasmic exosome-Ski2 complex degrading a RNA substrate | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Antiviral helicase SKI2, Exosome complex component CSL4, ... | Authors: | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | Deposit date: | 2023-08-25 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83, 2023
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6SJJ
| A new modulated crystal structure of ANS complex of St John's wort Hyp-1 protein with 36 protein molecules in the asymmetric unit of the supercell | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-ANILINO-1-NAPHTHALENE SULFONATE, CITRATE ANION, ... | Authors: | Smietanska, J, Sliwiak, J, Gilski, M, Dauter, Z, Strzalka, R, Wolny, J, Jaskolski, M. | Deposit date: | 2019-08-13 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A new modulated crystal structure of the ANS complex of the St John's wort Hyp-1 protein with 36 protein molecules in the asymmetric unit of the supercell. Acta Crystallogr D Struct Biol, 76, 2020
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8QY9
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6SKP
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8QYB
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6SZI
| ASR Alternansucrase in complex with isomaltose | Descriptor: | Alternansucrase, CALCIUM ION, alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose | Authors: | Cioci, G, Molina, M, Moulis, C, Remaud-Simeon, M. | Deposit date: | 2019-10-02 | Release date: | 2020-06-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A specific oligosaccharide-binding site in the alternansucrase catalytic domain mediates alternan elongation. J.Biol.Chem., 295, 2020
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6S8O
| Human Brr2 Helicase Region M641C/A1582C | Descriptor: | U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Vester, K, Santos, K.F, Wahl, M.C. | Deposit date: | 2019-07-10 | Release date: | 2020-01-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.172 Å) | Cite: | The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit. J.Biol.Chem., 295, 2020
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6T16
| ASR Alternansucrase in complex with panose | Descriptor: | Alternansucrase, CALCIUM ION, alpha-D-glucopyranose, ... | Authors: | Cioci, G, Molina, M, Moulis, C, Remaud-Simeon, M. | Deposit date: | 2019-10-03 | Release date: | 2020-06-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A specific oligosaccharide-binding site in the alternansucrase catalytic domain mediates alternan elongation. J.Biol.Chem., 295, 2020
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8QJS
| VHL/Elongin B/Elongin C complex with compound 155 | Descriptor: | (2S,4R)-1-[(2R)-2-[3-[2-(2-methoxyethoxy)ethoxy]-1,2-oxazol-5-yl]-3-methyl-butanoyl]-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | Authors: | Kerry, P.S, Hole, A.J, Perez-Dorado, J.I. | Deposit date: | 2023-09-13 | Release date: | 2024-01-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.191 Å) | Cite: | PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. J.Med.Chem., 67, 2024
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6SKR
| OXA-10_ETP. Structural insight to the enhanced carbapenem efficiency of OXA-655 compared to OXA-10. | Descriptor: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, FORMIC ACID, ... | Authors: | Leiros, H.-K.S. | Deposit date: | 2019-08-16 | Release date: | 2019-09-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural insights into the enhanced carbapenemase efficiency of OXA-655 compared to OXA-10. Febs Open Bio, 10, 2020
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3QP3
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6QXP
| Protein peptide complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat extensin-like protein 2, ... | Authors: | Moussu, S, Caroline, C, Santos-Fernandez, G, Wehrle, S, Grossniklaus, U, Santiago, J. | Deposit date: | 2019-03-07 | Release date: | 2020-03-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.201 Å) | Cite: | Structural basis for recognition of RALF peptides by LRX proteins during pollen tube growth. Proc.Natl.Acad.Sci.USA, 117, 2020
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6QWS
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6QQ7
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