6SKR

OXA-10_ETP. Structural insight to the enhanced carbapenem efficiency of OXA-655 compared to OXA-10.

Summary for 6SKR

• Entry DOI: 10.2210/pdb6skr/pdb
• Related: 6SKP 6SKQ
• Descriptor: Beta-lactamase, (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, FORMIC ACID, ... (5 entities in total)
• Functional Keywords: class d beta-lactamase, crystal structures, carbapenemases, antibiotic resistance., antibiotic
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 60259.16

Authors

Leiros, H.-K.S. (deposition date: 2019-08-16, release date: 2019-09-18, Last modification date: 2024-01-24)

• Primary citation: Leiros, H.S.,Thomassen, A.M.,Samuelsen, O.,Flach, C.F.,Kotsakis, S.D.,Larsson, D.G.J.; Structural insights into the enhanced carbapenemase efficiency of OXA-655 compared to OXA-10.; Febs Open Bio, 10:1821-1832, 2020; PubMed: 32683794; DOI: 10.1002/2211-5463.12935

Experimental method

X-RAY DIFFRACTION (1.85 Å)