4U4G
| Structure of GluA2* in complex with competitive antagonist ZK 200775 | Descriptor: | Glutamate receptor 2, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | Authors: | Yelshanskaya, M.V, Li, M, Sobolevsky, A.I. | Deposit date: | 2014-07-23 | Release date: | 2014-10-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4.49 Å) | Cite: | Structure of an agonist-bound ionotropic glutamate receptor. Science, 345, 2014
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8AYZ
| Poliovirus type 2 (strain MEF-1) virus-like particle in complex with capsid binder compound 17 | Descriptor: | 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid, Capsid protein, VP0, ... | Authors: | Bahar, M.W, Fry, E.E, Stuart, D.I. | Deposit date: | 2022-09-04 | Release date: | 2022-12-07 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (1.88 Å) | Cite: | A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation. Commun Biol, 5, 2022
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6TRP
| Solution Structure of Docking Domain Complex of Pax NRPS: PaxC NDD - PaxB CDD | Descriptor: | Peptide synthetase XpsB,Peptide synthetase XpsB | Authors: | Watzel, J, Hacker, C, Duchardt-Ferner, E, Bode, H.B, Woehnert, J. | Deposit date: | 2019-12-19 | Release date: | 2020-08-12 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | A New Docking Domain Type in the Peptide-Antimicrobial-Xenorhabdus Peptide Producing Nonribosomal Peptide Synthetase fromXenorhabdus bovienii. Acs Chem.Biol., 15, 2020
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6TXT
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4W7S
| Crystal structure of the yeast DEAD-box splicing factor Prp28 at 2.54 Angstroms resolution | Descriptor: | GLYCEROL, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ... | Authors: | Jacewicz, A, Smith, P, Schwer, B, Shuman, S. | Deposit date: | 2014-08-22 | Release date: | 2014-10-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.542 Å) | Cite: | Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28. Nucleic Acids Res., 42, 2014
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6D7L
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7PQQ
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8FE4
| Structure of dengue virus (DENV2) in complex with prM13, an anti-PrM monoclonal antibody | Descriptor: | Envelope protein E, prM protein, prM13 Fab Heavy Chain, ... | Authors: | Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. | Deposit date: | 2022-12-05 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (9.8 Å) | Cite: | prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proc.Natl.Acad.Sci.USA, 120, 2023
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7UIO
| Mediator-PIC Early (Composite Model) | Descriptor: | ALANINE, ASPARTIC ACID, DNA (37-MER), ... | Authors: | Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K. | Deposit date: | 2022-03-29 | Release date: | 2023-03-01 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol.Cell, 83, 2023
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8PKM
| Befiradol-bound serotonin 5-HT1A receptor - Gi Protein Complex | Descriptor: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, (3-chloranyl-4-fluoranyl-phenyl)-[4-fluoranyl-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone, 5-hydroxytryptamine receptor 1A, ... | Authors: | Schneider, J, Gmeiner, P, Hove, T.T, Rasmussen, T, Boettcher, B. | Deposit date: | 2023-06-27 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Discovery of a functionally selective serotonin 1A receptor agonist
for the treatment of pain To Be Published
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8PJK
| ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex | Descriptor: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 5-hydroxytryptamine receptor 1A, 6-[3-[2-(2-methoxyphenoxy)ethylamino]propoxy]-4~{H}-1,4-benzoxazin-3-one, ... | Authors: | Schneider, J, Gmeiner, P, Rasmussen, T, Boettcher, B. | Deposit date: | 2023-06-23 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Discovery of a functionally selective serotonin 1A receptor agonist
for the treatment of pain To Be Published
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6V1W
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6VRJ
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8DGK
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6W9N
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6Q6E
| Structural and functional insights into the condensin ATPase cycle | Descriptor: | Condensin complex subunit 2,Structural maintenance of chromosomes protein,Structural maintenance of chromosomes protein | Authors: | Simon, B, Hassler, M, Haering, C.H, Hennig, J. | Deposit date: | 2018-12-10 | Release date: | 2019-07-03 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural Basis of an Asymmetric Condensin ATPase Cycle. Mol.Cell, 74, 2019
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8E22
| VPS37A_21-148 | Descriptor: | Vacuolar protein sorting-associated protein 37A | Authors: | Tian, F, Ye, Y.S. | Deposit date: | 2022-08-12 | Release date: | 2023-08-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Identification of membrane curvature sensing motifs essential for VPS37A phagophore recruitment and autophagosome closure. Commun Biol, 7, 2024
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6L87
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7CQ1
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7CFV
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8EVG
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8SQB
| The cryo-EM structure of the EcBAM/EspP(beta7-12) complex | Descriptor: | Maltodextrin-binding protein,EspP(b7-12), Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | Authors: | Wu, R, Noinaj, N. | Deposit date: | 2023-05-04 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | BAM orchestrates OMP biogenesis using a beta-templating mechanism To Be Published
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6P4J
| Mouse norovirus complexed with GCDCA | Descriptor: | Capsid protein, GLYCOCHENODEOXYCHOLIC ACID | Authors: | Smith, T.J, Smith, T.J. | Deposit date: | 2019-05-27 | Release date: | 2019-08-07 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion. J.Virol., 93, 2019
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8FE3
| Structure of dengue virus (DENV2) in complex with prM12, an anti-PrM monoclonal antibody | Descriptor: | Envelope protein E, prM protein, prM12 Fab Heavy Chain, ... | Authors: | Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C. | Deposit date: | 2022-12-05 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (10.2 Å) | Cite: | prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proc.Natl.Acad.Sci.USA, 120, 2023
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6L7Z
| Solution NMR structure of the N-terminal immunoglobulin variable domain of BTNL2 | Descriptor: | Butyrophilin-like protein 2 | Authors: | Basak, A.J, Lee, W, Samanta, D, De, S. | Deposit date: | 2019-11-03 | Release date: | 2020-10-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural Insights into N-terminal IgV Domain of BTNL2, a T Cell Inhibitory Molecule, Suggests a Non-canonical Binding Interface for Its Putative Receptors. J.Mol.Biol., 432, 2020
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