6J9E
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5YIX
| Caulobacter crescentus GcrA sigma-interacting domain (SID) in complex with domain 2 of sigma 70 | Descriptor: | (R,R)-2,3-BUTANEDIOL, Cell cycle regulatory protein GcrA, RNA polymerase sigma factor RpoD, ... | Authors: | Wu, X, Zhang, Y. | Deposit date: | 2017-10-06 | Release date: | 2018-03-21 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.302 Å) | Cite: | Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA. Nucleic Acids Res., 46, 2018
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3MXN
| Crystal structure of the RMI core complex | Descriptor: | BENZAMIDINE, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | Authors: | Hoadley, K.A, Xu, D, Xue, Y, Satyshur, K.A, Wang, W, Keck, J.L. | Deposit date: | 2010-05-07 | Release date: | 2010-09-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome. Structure, 18, 2010
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2HZA
| Nickel-bound full-length Escherichia coli NikR | Descriptor: | 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, NICKEL (II) ION, Nickel-responsive regulator | Authors: | Schreiter, E.R, Drennan, C.L. | Deposit date: | 2006-08-08 | Release date: | 2006-08-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | NikR-operator complex structure and the mechanism of repressor activation by metal ions. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2CPG
| TRANSCRIPTIONAL REPRESSOR COPG | Descriptor: | CHLORIDE ION, TRANSCRIPTIONAL REPRESSOR COPG | Authors: | Gomis-Rueth, F.X, Sola, M, Acebo, P, Parraga, A, Guasch, A, Eritja, R, Gonzalez, A, Espinosa, M, del Solar, G, Coll, M. | Deposit date: | 1999-11-15 | Release date: | 1999-11-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator. EMBO J., 17, 1998
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6NIF
| crystal structure of human REV7-RAN complex | Descriptor: | hREV7, GTP-binding nuclear protein Ran, hREV3 fusion | Authors: | Wang, X, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. | Deposit date: | 2018-12-27 | Release date: | 2019-09-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch. J.Biol.Chem., 294, 2019
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3DNU
| structure of MDT protein | Descriptor: | CHLORIDE ION, PHOSPHATE ION, Protein hipA | Authors: | schumacher, M.A. | Deposit date: | 2008-07-02 | Release date: | 2009-01-27 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science, 323, 2009
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3ECH
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2QQF
| Hst2 bound to ADP-HPD and Acetylated histone H4 | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B.D, Zhao, K, Slama, J. | Deposit date: | 2007-07-26 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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8D79
| Crystal structure of a four-tetrad, parallel, and Na+ stabilized Tetrahymena thermophila telomeric G-quadruplex in complex with N-methyl mesoporphyrin IX | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3'), N-METHYLMESOPORPHYRIN, ... | Authors: | Chen, E.V, Beseiso, D, Yatsunyk, L.A. | Deposit date: | 2022-06-07 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Biophysical and structural characterization of telomeric G-quadruplexes from Tetrahymena thermophila in complex with N-Methyl Mesoporphyrin IX To Be Published
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8W9C
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4G8X
| G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex | Descriptor: | ORF067, RNA polymerase sigma factor rpoD | Authors: | Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A. | Deposit date: | 2012-07-23 | Release date: | 2013-08-07 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein. Cell(Cambridge,Mass.), 151, 2012
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4G6D
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4G94
| G1 ORF67 / Staphyloccus aureus sigmaA domain 4 complex | Descriptor: | ORF067, RNA polymerase sigma factor rpoD | Authors: | Darst, S.A, Osmundson, J.S, Montero-Diaz, C.M, Hochschild, A. | Deposit date: | 2012-07-23 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9971 Å) | Cite: | Promoter-specific transcription inhibition in Staphylococcus aureus by a phage protein. Cell(Cambridge,Mass.), 151, 2012
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2XDN
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4YG7
| Structure of FL autorepression promoter complex | Descriptor: | Antitoxin HipB, DNA (50-MER), Serine/threonine-protein kinase HipA | Authors: | Schumacher, M.A. | Deposit date: | 2015-02-25 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.77 Å) | Cite: | HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature, 524, 2015
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4J2X
| CSL (RBP-Jk) with corepressor KyoT2 bound to DNA | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3', ... | Authors: | Collins, K.J, Kovall, R.A. | Deposit date: | 2013-02-05 | Release date: | 2013-11-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch Signaling. Structure, 22, 2014
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2FE3
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7A1F
| Crystal structure of human 5' exonuclease Appollo in complex with 5'dAMP | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 5' exonuclease Apollo, FE (III) ION, ... | Authors: | Newman, J.A, Baddock, H.T, Mukhopadhyay, S.M.M, Burgess-Brown, N.A, von Delft, F, Arrowshmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-08-12 | Release date: | 2021-01-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family. Nucleic Acids Res., 49, 2021
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3BKF
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7A5F
| Structure of the stalled human mitoribosome with P- and E-site mt-tRNAs | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
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8DQ0
| Quorum-sensing receptor RhlR bound to PqsE | Descriptor: | 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, RhlR protein | Authors: | Paczkowski, J.E, Fromme, J.C, Feathers, J.R. | Deposit date: | 2022-07-18 | Release date: | 2022-12-07 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | Structure of the RhlR-PqsE complex from Pseudomonas aeruginosa reveals mechanistic insights into quorum-sensing gene regulation. Structure, 30, 2022
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4M6B
| Crystal structure of yeast Swr1-Z domain in complex with H2A.Z-H2B dimer | Descriptor: | Chimera protein of Histone H2B.1 and Histone H2A.Z, Helicase SWR1 | Authors: | Hong, J.J, Feng, H.Q, Wang, F, Ranjan, A, Chen, J.H, Jiang, J.S, Girlando, R, Xiao, T.S, Wu, C, Bai, Y.W. | Deposit date: | 2013-08-09 | Release date: | 2014-02-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The Catalytic Subunit of the SWR1 Remodeler Is a Histone Chaperone for the H2A.Z-H2B Dimer. Mol.Cell, 53, 2014
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3VPR
| Crystal Structure of a TetR Family Transcriptional Regulator PfmR from Thermus thermophilus HB8 | Descriptor: | Transcriptional regulator, TetR family | Authors: | Agari, Y, Sakamoto, K, Kuramitsu, S, Shinkai, A. | Deposit date: | 2012-03-12 | Release date: | 2012-07-11 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Transcriptional repression mediated by a TetR family protein, PfmR, from Thermus thermophilus HB8 J.Bacteriol., 2012
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7B5G
| Crystal structure of E.coli LexA in complex with nanobody NbSOS3(Nb14527) | Descriptor: | 1,2-ETHANEDIOL, LexA repressor, Nanobody Nb14527, ... | Authors: | Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L. | Deposit date: | 2020-12-03 | Release date: | 2022-09-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway. Structure, 30, 2022
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