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1AWU
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CYPA COMPLEXED WITH HVGPIA (PSEUDO-SYMMETRIC MONOMER)
Descriptor: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN
Authors:Vajdos, F.F.
Deposit date:1997-10-05
Release date:1998-03-18
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein.
Protein Sci., 6, 1997
1BT6
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P11 (S100A10), LIGAND OF ANNEXIN II IN COMPLEX WITH ANNEXIN II N-TERMINUS
Descriptor: ANNEXIN II, S100A10
Authors:Rety, S, Sopkova, J, Renouard, M, Osterloh, D, Gerke, V, Russo-Marie, F, Lewit-Bentley, A.
Deposit date:1998-09-02
Release date:1999-01-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of a complex of p11 with the annexin II N-terminal peptide.
Nat.Struct.Biol., 6, 1999
1M9Y
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A,G89A Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-30
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1MQ4
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Crystal Structure of Aurora-A Protein Kinase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AURORA-RELATED KINASE 1, MAGNESIUM ION, ...
Authors:Nowakowski, J, Cronin, C.N, McRee, D.E, Knuth, M.W, Nelson, C, Pavletich, N.P, Rodgers, J, Sang, B.-C, Scheibe, D.N, Swanson, R.V, Thompson, D.A.
Deposit date:2002-09-13
Release date:2003-09-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of the Cancer-Related Aurora-A, FAK and EphA2 Protein Kinases from Nanovolume Crystallography
Structure, 10, 2002
1MUO
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CRYSTAL STRUCTURE OF AURORA-2, AN ONCOGENIC SERINE-THREONINE KINASE
Descriptor: ADENOSINE, Aurora-related kinase 1
Authors:Cheetham, G.M.T, Knegtel, R.M.A, Coll, J.T, Renwick, S.B, Swenson, L, Weber, P, Lippke, J.A, Austen, D.A.
Deposit date:2002-09-24
Release date:2003-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of Aurora-2, an Oncogenic Serine/Threonine Kinase
J.Biol.Chem., 277, 2002
1N41
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Crystal Structure of Annexin V K27E Mutant
Descriptor: CALCIUM ION, SULFATE ION, annexin V
Authors:Mo, Y.D, Campos, B, Mealy, T.R, Commodore, L, Head, J.F, Dedman, J.R, Seaton, B.A.
Deposit date:2002-10-30
Release date:2003-02-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces
J.Biol.Chem., 278, 2003
1N44
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Crystal Structure of Annexin V R23E Mutant
Descriptor: Annexin V, CALCIUM ION, SULFATE ION
Authors:Mo, Y.D, Campos, B, Mealy, T.R, Commodore, L, Head, J.F, Dedman, J.R, Seaton, B.A.
Deposit date:2002-10-30
Release date:2003-02-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Interfacial basic cluster in anexin V couples phospholipid binding and trimer formation on membrane surfaces
J.Biol.Chem., 278, 2003
1NF7
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Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide
Descriptor: Inosine-5'-monophosphate dehydrogenase 2, POTASSIUM ION, RIBAVIRIN MONOPHOSPHATE, ...
Authors:Risal, D, Strickler, M.D, Goldstein, B.M.
Deposit date:2002-12-13
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Human Inosine Monophosphate Dehydrogenase type II complexed with the MPA/NAD analog C2-MAD
To be Published
1M9C
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-28
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1M63
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Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes
Descriptor: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CYCLOSPORIN A, ...
Authors:Huai, Q, Kim, H.-Y, Liu, Y, Zhao, Y, Mondragon, A, Liu, J.O, Ke, H.
Deposit date:2002-07-12
Release date:2002-09-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes
Proc.Natl.Acad.Sci.USA, 99, 2002
1NFK
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STRUCTURE OF THE NUCLEAR FACTOR KAPPA-B (NF-KB) P50 HOMODIMER
Descriptor: DNA (5'-D(*TP*GP*GP*GP*AP*AP*TP*TP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB))
Authors:Ghosh, G, Van Duyne, G, Ghosh, S, Sigler, P.B.
Deposit date:1995-02-28
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of NF-kappa B p50 homodimer bound to a kappa B site.
Nature, 373, 1995
1LE9
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BU of 1le9 by Molmil
Crystal structure of a NF-kB heterodimer bound to the Ig/HIV-kB siti
Descriptor: 5'-D(*AP*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*C)-3', 5'-D(*TP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*T)-3', NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT, ...
Authors:Benjamin, B, Huang, D.B, Chen-Park, F.E, Sigler, P.B, Ghosh, G.
Deposit date:2002-04-09
Release date:2003-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site.
J.Biol.Chem., 277, 2002
1OCA
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BU of 1oca by Molmil
HUMAN CYCLOPHILIN A, UNLIGATED, NMR, 20 STRUCTURES
Descriptor: CYCLOPHILIN A
Authors:Ottiger, M, Zerbe, O, Guntert, P, Wuthrich, K.
Deposit date:1997-07-07
Release date:1997-11-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The NMR solution conformation of unligated human cyclophilin A.
J.Mol.Biol., 272, 1997
1M9D
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BU of 1m9d by Molmil
X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) O-type chimera Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-28
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1OOA
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BU of 1ooa by Molmil
CRYSTAL STRUCTURE OF NF-kB(p50)2 COMPLEXED TO A HIGH-AFFINITY RNA APTAMER
Descriptor: Nuclear factor NF-kappa-B p105 subunit, RNA aptamer
Authors:Huang, D.B, Vu, D, Cassiday, L.A, Zimmerman, J.M, Maher III, L.J, Ghosh, G.
Deposit date:2003-03-03
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer.
Proc.Natl.Acad.Sci.USA, 100, 2003
1MIK
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BU of 1mik by Molmil
THE ROLE OF WATER MOLECULES IN THE STRUCTURE-BASED DESIGN OF (5-HYDROXYNORVALINE)-2-CYCLOSPORIN: SYNTHESIS, BIOLOGICAL ACTIVITY, AND CRYSTALLOGRAPHIC ANALYSIS WITH CYCLOPHILIN A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V.
Deposit date:1995-09-20
Release date:1996-03-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:The Role of Water Molecules in the Structure-Based Design of (5-Hydroxynorvaline)-2-Cyclosporin: Synthesis, Biological Activity, and Crystallographic Analysis with Cyclophilin A.
J.Med.Chem., 38, 1995
1MF8
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Crystal Structure of human calcineurin complexed with cyclosporin A and human cyclophilin
Descriptor: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CALMODULIN-DEPENDENT CALCINEURIN A SUBUNIT, ...
Authors:Jin, L, Harrison, S.C.
Deposit date:2002-08-09
Release date:2002-10-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of Human Calcineurin Complexed with Cyclosporin a and Human Cyclophilin
Proc.Natl.Acad.Sci.USA, 99, 2002
1MP1
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Solution structure of the PWI motif from SRm160
Descriptor: Ser/Arg-related nuclear matrix protein
Authors:Szymczyna, B.R, Bowman, J, McCracken, S, Pineda-Lucena, A, Lu, Y, Cox, B, Lambermon, M, Graveley, B.R, Arrowsmith, C.H, Blencowe, B.J.
Deposit date:2002-09-11
Release date:2003-09-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing.
Genes Dev., 17, 2003
1NMK
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The Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data
Descriptor: (13E,15E)-(3S,6S,9R,10R,11S,12S,18S,21S)-10,12-DIHYDROXY-3-(3-HYDROXYBEN-ZYL)-18-((E)-3-HYDROXY-1-METHYLPROPENYL)-6-ISOPROPYL-11-METHYL-9-(3-OXO-BUTYL)-19-OXA-1,4,7,25-TETRAAZA-BICYCLO[19.3.1]PENTACOSA-13,15-DIENE-2,5,8,20-TETRAONE, Peptidyl-prolyl cis-trans isomerase A
Authors:Kallen, J, Sedrani, R, Wagner, J.
Deposit date:2003-01-10
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data
J.Am.Chem.Soc., 125, 2003
1MKJ
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Human Kinesin Motor Domain With Docked Neck Linker
Descriptor: ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION, ...
Authors:Sindelar, C.V, Budny, M.J, Rice, S, Naber, N, Fletterick, R, Cooke, R.
Deposit date:2002-08-29
Release date:2002-10-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy.
Nat.Struct.Biol., 9, 2002
1M9X
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A,A88M,G89A Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-30
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1MCX
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STRUCTURE OF FULL-LENGTH ANNEXIN A1 IN THE PRESENCE OF CALCIUM
Descriptor: ANNEXIN I, CALCIUM ION
Authors:Luecke, H, Rosengarth, A.
Deposit date:2002-08-06
Release date:2003-03-04
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:A Calcium-driven Conformational Switch of the N-terminaland Core Domains of Annexin A1
J.Mol.Biol., 326, 2003
1M9E
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-28
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1OL6
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Structure of unphosphorylated D274N mutant of Aurora-A
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, SERINE/THREONINE KINASE 6
Authors:Bayliss, R, Conti, E.
Deposit date:2003-08-06
Release date:2003-10-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle.
Mol.Cell, 12, 2003
1OL7
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Structure of Human Aurora-A 122-403 phosphorylated on Thr287, Thr288
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SERINE/THREONINE KINASE 6
Authors:Bayliss, R, Conti, E.
Deposit date:2003-08-06
Release date:2003-10-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Mol.Cell, 12, 2003

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