PDB: 376 resultsInfo pagesStatus searchChemie searchBIRD

---

7CAL	Cryo-EM Structure of the Hyperpolarization-Activated Inwardly Rectifying Potassium Channel KAT1 from Arabidopsis Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Potassium channel KAT1 Authors: Li, S.Y, Yang, F, Sun, D.M, Zhang, Y, Zhang, M.G, Zhou, P, Liu, S.L, Zhang, Y.N, Zhang, L.H, Tian, C.L. Deposit date: 2020-06-09 Release date: 2020-07-29 Last modified: 2020-11-18 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis. Cell Res., 30, 2020
7N17	Structure of TAX-4_R421W apo open state Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel Authors: Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. Deposit date: 2021-05-27 Release date: 2022-03-16 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol, 5, 2022
7N15	Structure of TAX-4_R421W w/cGMP open state Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ... Authors: Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. Deposit date: 2021-05-27 Release date: 2022-03-16 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol, 5, 2022
7N16	Structure of TAX-4_R421W apo closed state Descriptor: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, SODIUM ION Authors: Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. Deposit date: 2021-05-27 Release date: 2022-03-16 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol, 5, 2022
6VY0	SthK P300A cyclic nucleotide-gated potassium channel in a putative active state, in complex with cAMP Descriptor: SthK Authors: Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M. Deposit date: 2020-02-25 Release date: 2020-11-11 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (6.68 Å) Cite: Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel. Nat Commun, 11, 2020
6WEJ	Structure of cGMP-unbound WT TAX-4 reconstituted in lipid nanodiscs Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ... Authors: Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J. Deposit date: 2020-04-02 Release date: 2020-06-03 Last modified: 2020-07-22 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nat.Struct.Mol.Biol., 27, 2020
6WEK	Structure of cGMP-bound WT TAX-4 reconstituted in lipid nanodiscs Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ... Authors: Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J. Deposit date: 2020-04-02 Release date: 2020-06-03 Last modified: 2020-07-22 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nat.Struct.Mol.Biol., 27, 2020
6WJG	PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma Descriptor: DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit Authors: Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S. Deposit date: 2020-04-13 Release date: 2020-12-02 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma. Plos Biol., 18, 2020
7O4H	The structure of the native CNGA1/CNGB1 CNG channel from retinal rods Descriptor: Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1 Authors: Barret, D.C.A, Marino, J. Deposit date: 2021-04-06 Release date: 2022-01-12 Last modified: 2022-02-02 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: The structure of the native CNGA1/CNGB1 CNG channel from bovine retinal rods. Nat.Struct.Mol.Biol., 29, 2022
6WEL	Structure of cGMP-unbound F403V/V407A mutant TAX-4 reconstituted in lipid nanodiscs Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ... Authors: Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J. Deposit date: 2020-04-02 Release date: 2020-06-03 Last modified: 2020-07-22 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel. Nat.Struct.Mol.Biol., 27, 2020
6WJF	PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma Descriptor: DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit Authors: Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S. Deposit date: 2020-04-13 Release date: 2020-12-02 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (7.5 Å) Cite: Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma. Plos Biol., 18, 2020
7FEW	Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr Authors: Chew, B.L.A, Luo, D. Deposit date: 2021-07-22 Release date: 2022-07-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr. Comput Struct Biotechnol J, 21, 2023
7FF9	Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I) Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ... Authors: Chew, B.L.A, Luo, D. Deposit date: 2021-07-23 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr To Be Published
7FF0	Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GOLD ION, SULFATE ION, ... Authors: Chew, B.L.A, Luo, D. Deposit date: 2021-07-22 Release date: 2022-07-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr. Comput Struct Biotechnol J, 21, 2023
7FF8	Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I) Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ... Authors: Chew, B.L.A, Luo, D. Deposit date: 2021-07-22 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr To Be Published
7ETS	Crystal structure of crp protein from Gardnerella Vaginalis Descriptor: Crp/Fnr family transcriptional regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Dong, H.J, Wang, S, Zhang, J.M, Gu, L. Deposit date: 2021-05-13 Release date: 2022-04-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Crystal structure of crp protein from Gardnerella Vaginalis To Be Published
5CIZ	E. coli RNA polymerase alpha subunit CTD in complex with CAP and DNA: A(5)-tract binding site for alpha CTD Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*CP*AP*AP*AP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*TP*TP*TP*GP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3'), ... Authors: Napoli, A.A, Lawson, C.L. Deposit date: 2015-07-13 Release date: 2016-06-29 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (5.0098 Å) Cite: The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element Biochemistry, 2020
5CVR	Crystal structure of FNR of A. fischeri in a partially degraded form Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, FE2/S2 (INORGANIC) CLUSTER, FNR type regulator Authors: Volbeda, A, Fontecilla-Camps, J.C. Deposit date: 2015-07-27 Release date: 2015-12-16 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium. Sci Adv, 1, 2015
1ZRE	4 crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-[6G;17C]ICAP38 DNA Descriptor: 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*GP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*CP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... Authors: Berman, H.M, Napoli, A.A. Deposit date: 2005-05-19 Release date: 2006-03-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps. J.Mol.Biol., 357, 2006
1ZRC	4 Crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-ICAP38 DNA Descriptor: 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... Authors: Berman, H.M, Napoli, A.A. Deposit date: 2005-05-19 Release date: 2006-03-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps. J.Mol.Biol., 357, 2006
1ZYB	Crystal structure of transcription regulator from Bacteroides thetaiotaomicron VPI-5482 at 2.15 A resolution Descriptor: GLYCEROL, transcription regulator, CRP family Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2005-06-09 Release date: 2005-07-19 Last modified: 2023-01-25 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of transcription regulator from Bacteroides thetaiotaomicron VPI-5482 at 2.15 A resolution To be published
1ZRF	4 crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-[6C;17G]ICAP38 DNA Descriptor: 1,4-DIETHYLENE DIOXIDE, 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ... Authors: Berman, H.M, Napoli, A.A. Deposit date: 2005-05-19 Release date: 2006-03-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps. J.Mol.Biol., 357, 2006
1ZRD	4 crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-[6A;17T]ICAP38 DNA Descriptor: 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*AP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*TP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... Authors: Berman, H.M, Napoli, A.A. Deposit date: 2005-05-19 Release date: 2006-03-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps. J.Mol.Biol., 357, 2006
3TNQ	Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein kinase, ... Authors: Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S. Deposit date: 2011-09-01 Release date: 2012-02-01 Last modified: 2012-09-26 Method: X-RAY DIFFRACTION (3.097 Å) Cite: Structure and allostery of the PKA RIIbeta tetrameric holoenzyme Science, 335, 2012
3TNP	Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit Authors: Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S. Deposit date: 2011-09-01 Release date: 2012-02-01 Last modified: 2013-02-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure and allostery of the PKA RIIbeta tetrameric holoenzyme Science, 335, 2012

<12345678910111213141516>