1YTW
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![BU of 1ytw by Molmil](/molmil-images/mine/1ytw) | YERSINIA PTPASE COMPLEXED WITH TUNGSTATE | Descriptor: | SULFATE ION, TUNGSTATE(VI)ION, YERSINIA PROTEIN TYROSINE PHOSPHATASE | Authors: | Fauman, E.B, Schubert, H.L, Saper, M.A. | Deposit date: | 1996-05-01 | Release date: | 1996-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The X-ray crystal structures of Yersinia tyrosine phosphatase with bound tungstate and nitrate. Mechanistic implications. J.Biol.Chem., 271, 1996
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7OOE
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![BU of 7ooe by Molmil](/molmil-images/mine/7ooe) | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z321318226 | Descriptor: | AMP PHOSPHORAMIDATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | Deposit date: | 2021-05-27 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.369 Å) | Cite: | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
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2ECR
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![BU of 2ecr by Molmil](/molmil-images/mine/2ecr) | Crystal structure of the ligand-free form of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase | Descriptor: | flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase | Authors: | Kim, S.H, Hisano, T, Iwasaki, W, Ebihara, A, Miki, K. | Deposit date: | 2007-02-13 | Release date: | 2008-01-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity Proteins, 70, 2008
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3ZNI
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![BU of 3zni by Molmil](/molmil-images/mine/3zni) | Structure of phosphoTyr363-Cbl-b - UbcH5B-Ub - ZAP-70 peptide complex | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL-B, ... | Authors: | Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T. | Deposit date: | 2013-02-14 | Release date: | 2013-07-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Essentiality of a Non-Ring Element in Priming Donor Ubiquitin for Catalysis by a Monomeric E3. Nat.Struct.Mol.Biol., 20, 2013
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6PXV
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![BU of 6pxv by Molmil](/molmil-images/mine/6pxv) | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the extracellular region. | Descriptor: | Insulin, Insulin receptor | Authors: | Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. | Deposit date: | 2019-07-27 | Release date: | 2019-09-04 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
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3N9D
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![BU of 3n9d by Molmil](/molmil-images/mine/3n9d) | Monoclinic Structure of P. aeruginosa LigD phosphoesterase domain | Descriptor: | MANGANESE (II) ION, Probable ATP-dependent DNA ligase, SULFATE ION, ... | Authors: | Shuman, S, Nair, P, Smith, P. | Deposit date: | 2010-05-28 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily Proc.Natl.Acad.Sci.USA, 107, 2010
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1CB6
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![BU of 1cb6 by Molmil](/molmil-images/mine/1cb6) | STRUCTURE OF HUMAN APOLACTOFERRIN AT 2.0 A RESOLUTION. | Descriptor: | CHLORIDE ION, Lactotransferrin | Authors: | Jameson, G.B, Anderson, B.F, Norris, G.E, Thomas, D.H, Baker, E.N. | Deposit date: | 1999-03-01 | Release date: | 1999-03-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change. Acta Crystallogr.,Sect.D, 54, 1998
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6PXW
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![BU of 6pxw by Molmil](/molmil-images/mine/6pxw) | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the top part of the receptor complex. | Descriptor: | Insulin, Insulin receptor | Authors: | Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. | Deposit date: | 2019-07-28 | Release date: | 2019-09-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
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2OXI
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3I0C
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![BU of 3i0c by Molmil](/molmil-images/mine/3i0c) | Crystal structure of GTB C80S/C196S unliganded | Descriptor: | ABO glycosyltransferase | Authors: | Schuman, B, Persson, M, Landry, R.C, Polakowski, R, Weadge, J.T, Seto, N.O.L, Borisova, S, Palcic, M.M, Evans, S.V. | Deposit date: | 2009-06-25 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402, 2010
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3I0H
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![BU of 3i0h by Molmil](/molmil-images/mine/3i0h) | Crystal structure of GTB C80S/C196S/C209S unliganded | Descriptor: | ABO glycosyltransferase | Authors: | Schuman, B, Persson, M, Landry, R.C, Polakowski, R, Weadge, J.T, Seto, N.O.L, Borisova, S, Palcic, M.M, Evans, S.V. | Deposit date: | 2009-06-25 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402, 2010
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3N9B
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![BU of 3n9b by Molmil](/molmil-images/mine/3n9b) | Crystal Structure of the P. aeruginosa LigD phosphoesterase domain | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | Authors: | Shuman, S, Nair, P, Smith, P. | Deposit date: | 2010-05-28 | Release date: | 2010-08-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily Proc.Natl.Acad.Sci.USA, 107, 2010
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1RQA
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![BU of 1rqa by Molmil](/molmil-images/mine/1rqa) | Crystallographic Analysis of the Interaction of Nitric Oxide with Quaternary-T Human Hemoglobin. Beta W73E hemoglobin exposed to NO under anaerobic conditions | Descriptor: | Hemoglobin alpha chain, Hemoglobin beta chain, NITRIC OXIDE, ... | Authors: | Chan, N.-L, Kavanaugh, J.S, Rogers, P.H, Arnone, A. | Deposit date: | 2003-12-04 | Release date: | 2005-01-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Crystallographic analysis of the interaction of nitric oxide with quaternary-T human hemoglobin. Biochemistry, 43, 2004
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1D8F
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![BU of 1d8f by Molmil](/molmil-images/mine/1d8f) | CRYSTAL STRUCTURE OF MMP3 COMPLEXED WITH A PIPERAZINE BASED INHIBITOR. | Descriptor: | CALCIUM ION, N-HYDROXY-1-(4-METHOXYPHENYL)SULFONYL-4-BENZYLOXYCARBONYL-PIPERAZINE-2-CARBOXAMIDE, STROMELYSIN-1 PRECURSOR, ... | Authors: | Cheng, M.Y, De, B, Pikul, S, Almstead, N.G, Natchus, M.G, Anastasio, M.V, McPhail, S.J, Snider, C.E, Taiwo, Y.O, Chen, L.Y. | Deposit date: | 1999-10-22 | Release date: | 2000-10-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Design and synthesis of piperazine-based matrix metalloproteinase inhibitors. J.Med.Chem., 43, 2000
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7UVC
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![BU of 7uvc by Molmil](/molmil-images/mine/7uvc) | Rad6(P43L)-Bre1 Complex | Descriptor: | E3 ubiquitin-protein ligase BRE1, Ubiquitin-conjugating enzyme E2 2 | Authors: | Shukla, P.K, Chandrasekharan, M.B. | Deposit date: | 2022-04-29 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex. Nucleic Acids Res., 51, 2023
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1AXD
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![BU of 1axd by Molmil](/molmil-images/mine/1axd) | STRUCTURE OF GLUTATHIONE S-TRANSFERASE-I BOUND WITH THE LIGAND LACTOYLGLUTATHIONE | Descriptor: | GLUTATHIONE S-TRANSFERASE I, LACTOYLGLUTATHIONE | Authors: | Neuefeind, T, Huber, R, Dasenbrock, H, Prade, L, Bieseler, B. | Deposit date: | 1997-10-15 | Release date: | 1998-10-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of herbicide-detoxifying maize glutathione S-transferase-I in complex with lactoylglutathione: evidence for an induced-fit mechanism. J.Mol.Biol., 274, 1997
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1CK6
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![BU of 1ck6 by Molmil](/molmil-images/mine/1ck6) | BINDING MODE OF SALICYLHYDROXAMIC ACID TO ARTHROMYCES RAMOSUS PEROXIDASE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PROTEIN (PEROXIDASE), ... | Authors: | Fukuyama, K, Itakura, H. | Deposit date: | 1999-04-28 | Release date: | 1999-12-29 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Binding of salicylhydroxamic acid and several aromatic donor molecules to Arthromyces ramosus peroxidase, investigated by X-ray crystallography, optical difference spectroscopy, NMR relaxation, molecular dynamics, and kinetics. Biochemistry, 38, 1999
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4RQV
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4RSU
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![BU of 4rsu by Molmil](/molmil-images/mine/4rsu) | Crystal structure of the light and hvem complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | Authors: | Liu, W, Ramagoal, U.A, Himmel, D, Bonanno, J.B, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-11-11 | Release date: | 2015-02-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218, 2021
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1IDO
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![BU of 1ido by Molmil](/molmil-images/mine/1ido) | I-DOMAIN FROM INTEGRIN CR3, MG2+ BOUND | Descriptor: | INTEGRIN, MAGNESIUM ION | Authors: | Lee, J.-O, Liddington, R. | Deposit date: | 1996-03-12 | Release date: | 1996-08-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18). Cell(Cambridge,Mass.), 80, 1995
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1N73
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![BU of 1n73 by Molmil](/molmil-images/mine/1n73) | Fibrin D-Dimer, Lamprey complexed with the PEPTIDE LIGAND: GLY-HIS-ARG-PRO-AMIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrin alpha-1 chain, ... | Authors: | Yang, Z, Pandi, L, Doolittle, R.F. | Deposit date: | 2002-11-12 | Release date: | 2003-01-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The Crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface Biochemistry, 41, 2002
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4ND6
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![BU of 4nd6 by Molmil](/molmil-images/mine/4nd6) | Crystal structure of apo 3-nitro-tyrosine tRNA synthetase (5B) in the open form | Descriptor: | GLYCEROL, Tyrosine-tRNA ligase | Authors: | Cooley, R.B, Driggers, C.M, Karplus, P.A, Mehl, R.A. | Deposit date: | 2013-10-25 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases. Biochemistry, 53, 2014
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4RQK
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4NDA
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![BU of 4nda by Molmil](/molmil-images/mine/4nda) | Crystal structure of 3-nitro-tyrosine tRNA synthetase (5B) bound to 3-nitro-tyrosine | Descriptor: | GLYCEROL, META-NITRO-TYROSINE, SODIUM ION, ... | Authors: | Cooley, R.B, Driggers, C.M, Karplus, P.A, Mehl, R.A. | Deposit date: | 2013-10-25 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Improved Second-Generation 3-Nitro-tyrosine tRNA Synthetases. Biochemistry, 53, 2014
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1MI4
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![BU of 1mi4 by Molmil](/molmil-images/mine/1mi4) | Glyphosate insensitive G96A mutant EPSP synthase liganded with shikimate-3-phosphate | Descriptor: | 5-enolpyruvylshikimate-3-phosphate synthase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE | Authors: | Eschenburg, S, Healy, M.L, Priestman, M.A, Lushington, G.H, Schonbrunn, E. | Deposit date: | 2002-08-21 | Release date: | 2002-12-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | How the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvyl
shikimate-3-phosphate synthase from Escherichia coli. PLANTA, 216, 2002
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