8XDQ
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![BU of 8xdq by Molmil](/molmil-images/mine/8xdq) | O-methyltransferase from Lycoris aurea complexed with Mg and SAH | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ... | Authors: | Saw, Y.Y.H, Nakashima, Y, Morita, H. | Deposit date: | 2023-12-11 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
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8YB6
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![BU of 8yb6 by Molmil](/molmil-images/mine/8yb6) | Type I-EHNH Cascade complex | Descriptor: | 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ... | Authors: | Li, Z. | Deposit date: | 2024-02-11 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems. Mol.Cell, 2024
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8Y6I
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![BU of 8y6i by Molmil](/molmil-images/mine/8y6i) | P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in nanodisc | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, ATP-dependent translocase ABCB1,mNeonGreen, CHOLESTEROL, ... | Authors: | Hamaguchi-Suzuki, N, Adachi, N, Moriya, T, Kawasaki, M, Suzuki, K, Anzai, N, Senda, T, Murata, T. | Deposit date: | 2024-02-02 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Cryo-EM structure of P-glycoprotein bound to triple elacridar inhibitor molecules. Biochem.Biophys.Res.Commun., 709, 2024
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8XQL
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![BU of 8xql by Molmil](/molmil-images/mine/8xql) | Structure of human class T GPCR TAS2R14-miniGs/gust complex with Aristolochic acid A. | Descriptor: | 8-methoxy-6-nitro-naphtho[1,2-e][1,3]benzodioxole-5-carboxylic acid, CHOLESTEROL, Exo-alpha-sialidase,Taste receptor type 2 member 14,LgBiT, ... | Authors: | Hu, X.L, Wu, L.J, Hua, T, Liu, Z.J. | Deposit date: | 2024-01-05 | Release date: | 2024-07-10 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Bitter taste TAS2R14 activation by intracellular tastants and cholesterol. Nature, 631, 2024
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9B75
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![BU of 9b75 by Molmil](/molmil-images/mine/9b75) | |
9LDB
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![BU of 9ldb by Molmil](/molmil-images/mine/9ldb) | DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK | Descriptor: | LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ... | Authors: | Dunn, C.R, Holbrook, J.J, Muirhead, H. | Deposit date: | 1991-11-26 | Release date: | 1993-10-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Design and synthesis of new enzymes based on the lactate dehydrogenase framework. Philos.Trans.R.Soc.London,Ser.B, 332, 1991
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8ZCJ
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![BU of 8zcj by Molmil](/molmil-images/mine/8zcj) | Cryo-EM structure of the pasireotide-bound SSTR5-Gi complex | Descriptor: | 004-DTR-LYS-TYR-PHA-HYP, Beta-2 adrenergic receptor,Somatostatin receptor type 5,lgbit (fusion protein), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Li, Y.G, Meng, X.Y, Yang, X.R, Ling, S.L, Shi, P, Tian, C.L, Yang, F. | Deposit date: | 2024-04-29 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural insights into somatostatin receptor 5 bound with cyclic peptides. Acta Pharmacol.Sin., 2024
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4BJI
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![BU of 4bji by Molmil](/molmil-images/mine/4bji) | Sfc1-DBD | Descriptor: | TRANSCRIPTION FACTOR TAU SUBUNIT SFC1 | Authors: | Taylor, N.M.I, Baudin, F, von Scheven, G, Muller, C.W. | Deposit date: | 2013-04-18 | Release date: | 2013-07-31 | Last modified: | 2013-11-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | RNA Polymerase III-Specific General Transcription Factor Iiic Contains a Heterodimer Resembling Tfiif RAP30/RAP74. Nucleic Acids Res., 41, 2013
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8YH9
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![BU of 8yh9 by Molmil](/molmil-images/mine/8yh9) | Type I-FHNH Cascade complex | Descriptor: | 60-nt crRNA, Cas5f, Cas6f, ... | Authors: | Li, Z. | Deposit date: | 2024-02-27 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems. Mol.Cell, 2024
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9GAA
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![BU of 9gaa by Molmil](/molmil-images/mine/9gaa) | |
8YWX
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![BU of 8ywx by Molmil](/molmil-images/mine/8ywx) | |
8YJC
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![BU of 8yjc by Molmil](/molmil-images/mine/8yjc) | Structure of Vibrio vulnificus MARTX cysteine protease domain C3727A | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, INOSITOL HEXAKISPHOSPHATE, Multifunctional autoprocessing repeat-in-toxin (MARTX), ... | Authors: | Chen, L, Khan, H, Tan, L, Li, X, Zhang, G, Im, Y.J. | Deposit date: | 2024-03-01 | Release date: | 2024-07-10 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural basis of the activation of MARTX cysteine protease domain from Vibrio vulnificus. Plos One, 19, 2024
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9BDP
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![BU of 9bdp by Molmil](/molmil-images/mine/9bdp) | |
8XPM
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![BU of 8xpm by Molmil](/molmil-images/mine/8xpm) | Mature virion portal of phage lambda with DNA | Descriptor: | DNA (104-MER), DNA (92-MER), Head completion protein, ... | Authors: | Wang, J.W, Gu, Z.W. | Deposit date: | 2024-01-04 | Release date: | 2024-04-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural morphing in the viral portal vertex of bacteriophage lambda. J.Virol., 98, 2024
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8ZSV
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![BU of 8zsv by Molmil](/molmil-images/mine/8zsv) | Cryo-EM structure of the RO5263397-bound mTAAR1-Gs complex | Descriptor: | (4~{S})-4-(3-fluoranyl-2-methyl-phenyl)-1,3-oxazolidin-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Jiang, K.X, Zheng, Y, Xu, F. | Deposit date: | 2024-06-05 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | The versatile binding landscape of the TAAR1 pocket for LSD and other antipsychotic drug molecules. Cell Rep, 43, 2024
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8XRF
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![BU of 8xrf by Molmil](/molmil-images/mine/8xrf) | |
9B76
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![BU of 9b76 by Molmil](/molmil-images/mine/9b76) | |
8YHA
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![BU of 8yha by Molmil](/molmil-images/mine/8yha) | Type I-EHNH Cascade-ssDNA complex | Descriptor: | 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ... | Authors: | Li, Z. | Deposit date: | 2024-02-27 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems. Mol.Cell, 2024
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8XZQ
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![BU of 8xzq by Molmil](/molmil-images/mine/8xzq) | Crystal structure of folE riboswitch with 8-N Guanine | Descriptor: | 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, MAGNESIUM ION, RNA (53-MER), ... | Authors: | Li, C.Y, Ren, A.M. | Deposit date: | 2024-01-21 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch. Nucleic Acids Res., 2024
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8XZL
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![BU of 8xzl by Molmil](/molmil-images/mine/8xzl) | Crystal structure of folE riboswitch with DHF | Descriptor: | DIHYDROFOLIC ACID, MAGNESIUM ION, RNA (53-MER), ... | Authors: | Li, C.Y, Ren, A.M. | Deposit date: | 2024-01-21 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch. Nucleic Acids Res., 2024
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9BAQ
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![BU of 9baq by Molmil](/molmil-images/mine/9baq) | CryoEM structure of DIM2-HP1-H3K9me3-DNA complex | Descriptor: | DNA (5'-D(*AP*CP*TP*AP*CP*T)-R(P*(PYO))-D(P*CP*TP*CP*CP*TP*CP*CP*TP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*TP*AP*GP*T)-3'), DNA (cytosine-5-)-methyltransferase, ... | Authors: | Song, J, Shao, Z. | Deposit date: | 2024-04-04 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | CryoEM structure of DIM2-HP1-H3K9me3-DNA complex To Be Published
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9FYP
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![BU of 9fyp by Molmil](/molmil-images/mine/9fyp) | Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH. | Descriptor: | Alpha-synuclein, CHLORIDE ION | Authors: | Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. | Deposit date: | 2024-07-03 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2024
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5KWO
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![BU of 5kwo by Molmil](/molmil-images/mine/5kwo) | |
8XLP
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![BU of 8xlp by Molmil](/molmil-images/mine/8xlp) | Structure of inactive Photosystem II associated with CAC antenna from Rhodomonas Salina | Descriptor: | (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ... | Authors: | Si, L, Li, M. | Deposit date: | 2023-12-26 | Release date: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structure of inactive Photosystem II associated with CAC antenna from Rhodomonas Salina To Be Published
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9BDX
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![BU of 9bdx by Molmil](/molmil-images/mine/9bdx) | NF-kappaB RelA homo-dimer bound to CG-centric kappaB DNA | Descriptor: | DNA (5'-D(*AP*TP*CP*AP*CP*TP*GP*GP*AP*AP*GP*TP*TP*CP*CP*CP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*GP*GP*GP*AP*AP*CP*TP*TP*CP*CP*AP*GP*TP*GP*AP*T)-3'), Transcription factor p65 | Authors: | Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. | Deposit date: | 2024-04-12 | Release date: | 2024-04-24 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
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