8XQL

Structure of human class T GPCR TAS2R14-miniGs/gust complex with Aristolochic acid A.

Summary for 8XQL

Entry DOI	10.2210/pdb8xql/pdb
EMDB information	38580
Descriptor	Guanine nucleotide-binding protein G(t) subunit alpha-3, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
Functional Keywords	gpcr, tas2r14, minigsg, goq, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	204897.61
Authors	Hu, X.L.,Wu, L.J.,Hua, T.,Liu, Z.J. (deposition date: 2024-01-05, release date: 2024-07-10)
Primary citation	Hu, X.,Ao, W.,Gao, M.,Wu, L.,Pei, Y.,Liu, S.,Wu, Y.,Zhao, F.,Sun, Q.,Liu, J.,Jiang, L.,Wang, X.,Li, Y.,Tan, Q.,Cheng, J.,Yang, F.,Yang, C.,Sun, J.,Hua, T.,Liu, Z.J. Bitter taste TAS2R14 activation by intracellular tastants and cholesterol. Nature, 2024 Cited by PubMed: 38776963 DOI: 10.1038/s41586-024-07569-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.99 Å)

Structure validation