PDB: 19260 resultsInfo pagesStatus searchChemie searchBIRD

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4DYZ	Crystal Structure of the apo form of Human H-Ferritin variant MIC1 Descriptor: CALCIUM ION, COPPER (II) ION, Ferritin heavy chain Authors: Tezcan, F.A, Huard, D.J.E. Deposit date: 2012-02-29 Release date: 2013-01-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Re-engineering protein interfaces yields copper-inducible ferritin cage assembly. Nat.Chem.Biol., 9, 2013
4DZ9	hCA II in complex with novel sulfonamide inhibitors Set D Descriptor: 4-[4-(cyclohexylmethyl)-1H-1,2,3-triazol-1-yl]-2,3,5,6-tetrafluorobenzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Aggarwal, M, McKenna, R. Deposit date: 2012-02-29 Release date: 2013-03-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.491 Å) Cite: hCA II in complex with novel sulfonamide inhibitors Set D To be Published
4DZ4	X-ray crystal structure of a hypothetical Agmatinase from Burkholderia thailandensis Descriptor: 1,2-ETHANEDIOL, Agmatinase, MANGANESE (II) ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-02-29 Release date: 2012-03-28 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
4E2L	Crystal Structure of the periplasmic domain of mutant FepE LPS O-antigen chain length regulator protein Descriptor: Ferric enterobactin (Enterochelin) transport Authors: Kalynych, S, Yao, D, Magee, J.D, Cygler, M. Deposit date: 2012-03-08 Release date: 2012-03-28 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Characterization of Closely Related O-antigen Lipopolysaccharide (LPS) Chain Length Regulators. J.Biol.Chem., 287, 2012
4E0M	SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form I) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION Authors: Zhao, M, Liu, C, Michael, S.R, Eisenberg, D. Deposit date: 2012-03-04 Release date: 2013-02-13 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates Proc.Natl.Acad.Sci.USA, 109, 2012
4E3I	Crystal structure of AmpC beta-lactamase in complex with a designed 3-carboxyl benzyl sulfonamide boronic acid inhibitor Descriptor: 3-({[(dihydroxyboranyl)methyl]sulfamoyl}methyl)benzoic acid, Beta-lactamase, PHOSPHATE ION Authors: Eidam, O, Shoichet, B.K. Deposit date: 2012-03-09 Release date: 2012-09-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E3W	Crystal Structure Francisella tularensis histidine acid phosphatase cryoprotected with proline Descriptor: Acid phosphatase, PROLINE, SULFATE ION Authors: Tanner, J.J, Pemberton, T.A. Deposit date: 2012-03-10 Release date: 2012-07-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Proline: Mother Nature's cryoprotectant applied to protein crystallography. Acta Crystallogr.,Sect.D, 68, 2012
4DWG	Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-heptylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, Farnesyl pyrophosphate synthase, ... Authors: Aripirala, S, Amzel, L.M, Gabelli, S.B. Deposit date: 2012-02-24 Release date: 2013-01-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
4E3V	Crystal Structure of XYLOSE ISOMERASE FROM STREPTOMYCES RUBIGINOSUS Cryoprotected in Proline Descriptor: MAGNESIUM ION, MANGANESE (II) ION, PROLINE, ... Authors: Tanner, J.J, Pemberton, T.A. Deposit date: 2012-03-10 Release date: 2012-07-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.503 Å) Cite: Proline: Mother Nature's cryoprotectant applied to protein crystallography. Acta Crystallogr.,Sect.D, 68, 2012
4DX8	ICAP1 in complex with KRIT1 N-terminus Descriptor: BROMIDE ION, Integrin beta-1-binding protein 1, Krev interaction trapped protein 1 Authors: Liu, W, Draheim, K, Zhang, R, Calderwood, D.A, Boggon, T.J. Deposit date: 2012-02-27 Release date: 2013-01-09 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation. Mol.Cell, 49, 2013
4DY6	Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with 2'-phosphate bis(adenosine)-5'-diphosphate Descriptor: CITRIC ACID, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, inorganic polyphosphate/ATP-NAD kinase 1 Authors: Poncet-Montange, G, Assairi, L, Arold, S, Pochet, S, Labesse, G. Deposit date: 2012-02-28 Release date: 2012-03-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: NAD kinases use substrate-assisted catalysis for specific recognition of NAD. J.Biol.Chem., 282, 2007
4DYK	Crystal structure of an adenosine deaminase from pseudomonas aeruginosa pao1 (target nysgrc-200449) with bound zn Descriptor: AMIDOHYDROLASE, GLYCEROL, MAGNESIUM ION, ... Authors: Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Chamala, S, Kar, A, Lafleur, J, Villigas, G, Evans, B, Hammonds, J, Gizzi, A, Zencheck, W.D, Hillerich, B, Love, J, Seidel, R.D, Bonanno, J.B, Raushel, F.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2012-02-29 Release date: 2012-03-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of an adenosine deaminase from pseudomonas aeruginosa pao1 (target nysgrc-200449) with bound zn to be published
4E0D	Binary complex of Bacillus DNA Polymerase I Large Fragment E658A and duplex DNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-03-02 Release date: 2012-06-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. J.Biol.Chem., 287, 2012
4E2E	Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide (YWHAG) from Homo sapiens at 2.25 A resolution Descriptor: 1,2-ETHANEDIOL, 14-3-3 protein gamma Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2012-03-08 Release date: 2012-03-21 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activa tion protein, gamma polypeptide (YWHAG) from Homo sapiens at 2.25 A resolution To be published
4DZU	Complex of 3-alpha bound to gp41-5 Descriptor: 3-alpha, GLYCEROL, gp41-5 Authors: Johnson, L.M, Mortenson, D.E, Yun, H.G, Horne, W.S, Ketas, T.J, Lu, M, Moore, J.P, Gellman, S.H. Deposit date: 2012-03-01 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Enhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array. J.Am.Chem.Soc., 134, 2012
4E3L	Crystal structure of AmpC beta-lactamase in complex with a 3-chloro-4-tetrazolyl benzene sulfonamide boronic acid inhibitor Descriptor: Beta-lactamase, PHOSPHATE ION, [({[3-chloro-4-(1H-tetrazol-5-yl)phenyl]sulfonyl}amino)methyl]boronic acid Authors: Eidam, O, Shoichet, B.K. Deposit date: 2012-03-09 Release date: 2012-09-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Fragment-guided design of subnanomolar beta-lactamase inhibitors active in vivo. Proc.Natl.Acad.Sci.USA, 109, 2012
4E2H	Crystal structure of the periplasmic domain of Shigella flexneri WzzB Descriptor: Chain length determinant protein Authors: Kalynych, S, Yao, D, Magee, J.D, Cygler, M. Deposit date: 2012-03-08 Release date: 2012-03-28 Last modified: 2012-06-20 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Structural Characterization of Closely Related O-antigen Lipopolysaccharide (LPS) Chain Length Regulators. J.Biol.Chem., 287, 2012
4E2S	Crystal structure of (S)-Ureidoglycine Aminohydrolase from Arabidopsis thaliana in complex with its substrate, (S)-Ureidoglycine Descriptor: (2S)-amino(carbamoylamino)ethanoic acid, MANGANESE (II) ION, Ureidoglycine aminohydrolase Authors: Shin, I, Rhee, S. Deposit date: 2012-03-09 Release date: 2012-04-18 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana J.Biol.Chem., 287, 2012
4DX5	Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop Descriptor: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, DARPIN, ... Authors: Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M. Deposit date: 2012-02-27 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proc.Natl.Acad.Sci.USA, 109, 2012
4DZH	Crystal structure of an adenosine deaminase from xanthomonas campestris (target nysgrc-200456) with bound zn Descriptor: AMIDOHYDROLASE, GLYCEROL, MAGNESIUM ION, ... Authors: Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Chamala, S, Kar, A, Lafleur, J, Villigas, G, Evans, B, Hammonds, J, Gizzi, A, Zencheck, W.D, Hillerich, B, Love, J, Seidel, R.D, Bonanno, J.B, Raushel, F.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2012-03-01 Release date: 2012-03-21 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.552 Å) Cite: Crystal structure of an adenosine deaminase from xanthomonas campestris (target nysgrc-200456) with bound zn to be published
4E05	Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... Authors: Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. Deposit date: 2012-03-02 Release date: 2012-12-05 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.304 Å) Cite: Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc.Natl.Acad.Sci.USA, 109, 2012
4E19	Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1 Descriptor: MANGANESE (II) ION, ribonuclease H1 Authors: You, D.J, Angkawidjaja, C, Koga, Y, Kanaya, S. Deposit date: 2012-03-06 Release date: 2013-03-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1 To be Published
4E2G	Crystal structure of Cupin fold protein Sthe2323 from Sphaerobacter thermophilus Descriptor: ACETATE ION, Cupin 2 conserved barrel domain protein, NICKEL (II) ION, ... Authors: Chang, C, Hatzos-Skintges, C, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2012-03-08 Release date: 2012-03-21 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Crystal structure of Cupin fold protein Sthe2323 from Sphaerobacter thermophilus To be Published
4E1S	X-ray crystal structure of the transmembrane beta-domain from intimin from EHEC strain O157:H7 Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, ... Authors: Fairman, J.W, Dautin, N, Wojtowicz, D, Wei, L, Noinaj, N, Barnard, T.J, Udho, E, Finkelstein, A, Przytycka, T.M, Cherezov, V, Buchanan, S.K. Deposit date: 2012-03-07 Release date: 2012-06-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.855 Å) Cite: Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis. Structure, 20, 2012
4DLC	Crystal Structure of Trypanosoma brucei dUTPase with dUMP, MgF3- transition state analogue, and Mg2+ Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Deoxyuridine triphosphatase, MAGNESIUM ION, ... Authors: Hemsworth, G.R, Gonzalez-Pacanowska, D, Wilson, K.S. Deposit date: 2012-02-06 Release date: 2013-08-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.759 Å) Cite: On the catalytic mechanism of dimeric dUTPases. Biochem.J., 456, 2013

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