4DY6

Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with 2'-phosphate bis(adenosine)-5'-diphosphate

Replaces:  2I2E

Summary for 4DY6

Descriptorinorganic polyphosphate/ATP-NAD kinase 1, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, CITRIC ACID, ... (4 entities in total)
Functional Keywordslmnadk1, nad analog, inorganic polyphosphates, transferase
Biological sourceListeria monocytogenes
Cellular locationCytoplasm (By similarity) Q8Y8D7
Total number of polymer chains1
Total molecular weight31993.81
Authors
Poncet-Montange, G.,Assairi, L.,Arold, S.,Pochet, S.,Labesse, G. (deposition date: 2012-02-28, release date: 2012-03-07)
Primary citation
Poncet-Montange, G.,Assairi, L.,Arold, S.,Pochet, S.,Labesse, G.
NAD kinases use substrate-assisted catalysis for specific recognition of NAD.
J.Biol.Chem., 282:33925-33934, 2007
PubMed: 17686780 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M701394200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24360.4%3.6%2.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution