7F1E
| Structure of METTL6 bound with SAM | Descriptor: | S-ADENOSYLMETHIONINE, tRNA N(3)-methylcytidine methyltransferase METTL6 | Authors: | Li, S, Liao, S, Xu, C. | Deposit date: | 2021-06-09 | Release date: | 2022-01-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.589 Å) | Cite: | Structural basis for METTL6-mediated m3C RNA methylation. Biochem.Biophys.Res.Commun., 589, 2021
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8PIH
| Structure of Api m1 in complex with two nanobodies | Descriptor: | CHLORIDE ION, Phospholipase A2, nanobdoy AM1-1, ... | Authors: | Aagaard, J.B, Gandini, R, Spillner, E, Miehe, M, Andersen, G.R. | Deposit date: | 2023-06-21 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Nanobody-based IgG formats as blocking antibodies of the major honeybee venom allergen Api m 1 To be published
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4H9L
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7F83
| Crystal Structure of a receptor in Complex with inverse agonist | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone, Growth hormone secretagogue receptor type 1,Soluble cytochrome b562 | Authors: | Xu, Z, Shao, Z. | Deposit date: | 2021-07-01 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Molecular mechanism of agonism and inverse agonism in ghrelin receptor. Nat Commun, 13, 2022
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7BUA
| Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SIgN-3C Fab heavy chain, ... | Authors: | Zhang, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Lok, S.M. | Deposit date: | 2020-04-06 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | A Human Antibody Neutralizes Different Flaviviruses by Using Different Mechanisms. Cell Rep, 31, 2020
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7BV8
| Mature 50S ribosomal subunit from RrmJ knock out E.coli strain | Descriptor: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Wang, W, Li, W.Q, Ge, X.L, Yan, K.G, Mandava, C.S, Sanyal, S, Gao, N. | Deposit date: | 2020-04-09 | Release date: | 2020-07-01 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation. Proc.Natl.Acad.Sci.USA, 117, 2020
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7BYT
| Crystal structure of exo-beta-1,3-galactanase from Phanerochaete chrysosporium Pc1,3Gal43A with galactose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Matsuyama, K, Ishida, T, Kishine, N, Fujimoto, Z, Igarashi, K, Kaneko, S. | Deposit date: | 2020-04-24 | Release date: | 2020-11-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Unique active-site and subsite features in the arabinogalactan-degrading GH43 exo-beta-1,3-galactanase from Phanerochaete chrysosporium . J.Biol.Chem., 295, 2020
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8Q0F
| Inward-facing, open2 proteoliposome complex I at 3.1 A. Initially purified in DDM. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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5G09
| The crystal structure of a S-selective transaminase from Bacillus megaterium bound with R-alpha-methylbenzylamine | Descriptor: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | Authors: | van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. | Deposit date: | 2016-03-17 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases Biochemistry, 55, 2016
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7F81
| Structure of the bacterial cellulose synthase subunit Z from Enterobacter sp. CJF-002 | Descriptor: | GLYCEROL, Glucanase, S,R MESO-TARTARIC ACID | Authors: | Fujiwara, T, Fujishima, A, Yao, M. | Deposit date: | 2021-06-30 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural snapshot of a glycoside hydrolase family 8 endo-beta-1,4-glucanase capturing the state after cleavage of the scissile bond. Acta Crystallogr.,Sect.D, 78, 2022
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4GRW
| Structure of a complex of human IL-23 with 3 Nanobodies (Llama vHHs) | Descriptor: | Interleukin-12 subunit beta, Interleukin-23 subunit alpha, Nanobody 124C4, ... | Authors: | Desmyter, A, Spinelli, S, Button, C, Saunders, M, de Haard, H, Rommelaere, H, Union, A, Cambillau, C. | Deposit date: | 2012-08-27 | Release date: | 2014-02-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Neutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine-Nanobody Complex. Front Immunol, 8, 2017
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8POO
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7F8J
| Cryo-EM structure of human pannexin-1 in a nanodisc | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2021-07-02 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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8Q0Q
| Outward-facing, slack proteoliposome complex I at 3.6 A. Initially purified in DDM | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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8Q2P
| Structure of the membrane integral lipoprotein N-acyltransferase Lnt from E. coli by using Se-MAG for the the lipid cubic phase crystallization | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Apolipoprotein N-acyltransferase, ... | Authors: | Huang, C.-Y, Boland, C, Kaki, S.S, Wang, M, Olieric, V, Caffrey, M. | Deposit date: | 2023-08-03 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Se-MAG Is a Convenient Additive for Experimental Phasing and Structure Determination of Membrane Proteins Crystallised by the Lipid Cubic Phase (In Meso) Method Crystals, 2023
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8Q45
| Inward-facing, closed proteoliposome complex I at 2.7 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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5FQD
| Structural basis of Lenalidomide induced CK1a degradation by the crl4crbn ubiquitin ligase | Descriptor: | CASEIN KINASE I ISOFORM ALPHA, DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, ... | Authors: | Petzold, G, Fischer, E.S, Thoma, N.H. | Deposit date: | 2015-12-09 | Release date: | 2016-02-24 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural Basis of Lenalidomide-Induced Ck1Alpha Degradation by the Crl4(Crbn) Ubiquitin Ligase. Nature, 532, 2016
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7F82
| Structure of the bacterial cellulose synthase subunit Z in complex with cellooligosaccharides from Enterobacter sp. CJF-002 | Descriptor: | Glucanase, S,R MESO-TARTARIC ACID, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | Authors: | Fujiwara, T, Fujishima, A, Yao, M. | Deposit date: | 2021-06-30 | Release date: | 2022-02-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural snapshot of a glycoside hydrolase family 8 endo-beta-1,4-glucanase capturing the state after cleavage of the scissile bond. Acta Crystallogr.,Sect.D, 78, 2022
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8Q49
| Outward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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7F8O
| Cryo-EM structure of the C-terminal deletion mutant of human PANX1 in a nanodisc | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2021-07-02 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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8Q0A
| Inward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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8Q0O
| Outward-facing, open2 proteoliposome complex I at 3.1 A. Initially purified in DDM. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-07-28 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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8Q46
| Inward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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8Q4A
| Outward-facing, open1 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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7F8N
| Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2021-07-02 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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