5FQD
Structural basis of Lenalidomide induced CK1a degradation by the crl4crbn ubiquitin ligase
Summary for 5FQD
Entry DOI | 10.2210/pdb5fqd/pdb |
Descriptor | DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, CASEIN KINASE I ISOFORM ALPHA, ... (6 entities in total) |
Functional Keywords | ligase, dna binding |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 6 |
Total formula weight | 368753.44 |
Authors | Petzold, G.,Fischer, E.S.,Thoma, N.H. (deposition date: 2015-12-09, release date: 2016-02-24, Last modification date: 2024-01-10) |
Primary citation | Petzold, G.,Fischer, E.S.,Thoma, N.H. Structural Basis of Lenalidomide-Induced Ck1Alpha Degradation by the Crl4(Crbn) Ubiquitin Ligase. Nature, 532:127-, 2016 Cited by PubMed: 26909574DOI: 10.1038/NATURE16979 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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