1N48
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![BU of 1n48 by Molmil](/molmil-images/mine/1n48) | Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion | Descriptor: | 5'-D(*CP*AP*(3DR)P*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Ling, H, Boudsocq, F, Woodgate, R, Yang, W. | Deposit date: | 2002-10-30 | Release date: | 2004-02-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A Y-family polymerase complexed with abasic lesions: catching DNA with a loaded nucleoside triphosphate To be Published
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6RSW
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![BU of 6rsw by Molmil](/molmil-images/mine/6rsw) | HFD domain of mouse CAP1 bound to the pointed end of G-actin | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Kotila, T, Kogan, K, Lappalainen, P. | Deposit date: | 2019-05-22 | Release date: | 2019-11-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin. Nat Commun, 10, 2019
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3VQR
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![BU of 3vqr by Molmil](/molmil-images/mine/3vqr) | Structure of a dye-linked L-proline dehydrogenase mutant from the aerobic hyperthermophilic archaeon, Aeropyrum pernix | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Sakuraba, H, Ohshima, T, Satomura, T, Yoneda, K. | Deposit date: | 2012-03-29 | Release date: | 2012-04-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal Structure of Novel Dye-linked L-Proline Dehydrogenase from Hyperthermophilic Archaeon Aeropyrum pernix J.Biol.Chem., 287, 2012
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1VZ6
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4ZT9
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1MUU
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![BU of 1muu by Molmil](/molmil-images/mine/1muu) | 2.0 A crystal structure of GDP-mannose dehydrogenase | Descriptor: | GDP-mannose 6-dehydrogenase, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER, ... | Authors: | Snook, C.F, Tipton, P.A, Beamer, L.J. | Deposit date: | 2002-09-24 | Release date: | 2003-05-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Crystal structure of GDP-mannose dehydrogenase: A key enzyme of alginate biosynthesis in P. aeruginosa Biochemistry, 42, 2003
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1MVZ
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![BU of 1mvz by Molmil](/molmil-images/mine/1mvz) | NMR solution structure of a Bowman Birk inhibitor isolated from snail medic seeds (Medicago Scutellata) | Descriptor: | Bowman-Birk type protease inhibitor, (MSTI) | Authors: | Catalano, M, Ragona, L, Molinari, H, Tava, A, Zetta, L. | Deposit date: | 2002-09-27 | Release date: | 2003-04-22 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Anticarcinogenic Bowman Birk inhibitor isolated from snail medic seeds (Medicago Scutellata): solution structure and analysis of self-association behaviour Biochemistry, 42, 2003
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5AA7
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![BU of 5aa7 by Molmil](/molmil-images/mine/5aa7) | Structural and functional characterization of a chitin-active 15.5 kDa lytic polysaccharide monooxygenase domain from a modular chitinase from Jonesia denitrificans | Descriptor: | CHITINASE, COPPER (I) ION | Authors: | Mekasha, S, Forsberg, Z, Dalhus, B, Choudhary, S, Schmidt-Dannert, C, Vaaje-Kolstad, G, Eijsink, V. | Deposit date: | 2015-07-23 | Release date: | 2015-12-09 | Last modified: | 2017-09-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural and Functional Characterization of a Small Chitin-Active Lytic Polysaccharide Monooxygenase Domain of a Multi-Modular Chitinase from Jonesia Denitrificans. FEBS Lett., 590, 2016
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1IXX
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![BU of 1ixx by Molmil](/molmil-images/mine/1ixx) | CRYSTAL STRUCTURE OF COAGULATION FACTORS IX/X-BINDING PROTEIN (IX/X-BP) FROM VENOM OF HABU SNAKE WITH A HETERODIMER OF C-TYPE LECTIN DOMAINS | Descriptor: | CALCIUM ION, COAGULATION FACTORS IX/X-BINDING PROTEIN | Authors: | Mizuno, H, Fujimoto, Z, Koizumi, M, Kano, H. | Deposit date: | 1997-05-01 | Release date: | 1998-05-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of coagulation factors IX/X-binding protein, a heterodimer of C-type lectin domains. Nat.Struct.Biol., 4, 1997
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6RU5
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![BU of 6ru5 by Molmil](/molmil-images/mine/6ru5) | human complement C3 in complex with the hC3Nb1 nanobody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jensen, R.K, Andersen, G.R. | Deposit date: | 2019-05-27 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6RTI
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![BU of 6rti by Molmil](/molmil-images/mine/6rti) | X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with aptamer A9g | Descriptor: | (2S)-2-(PHOSPHONOMETHYL)PENTANEDIOIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Motlova, L, Kolenko, P, Barinka, C. | Deposit date: | 2019-05-24 | Release date: | 2020-06-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer. Nucleic Acids Res., 48, 2020
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6RU3
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3VS1
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![BU of 3vs1 by Molmil](/molmil-images/mine/3vs1) | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-phenylurea | Descriptor: | 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-phenylurea, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kuratani, M, Tomabechi, Y, Toyama, M, Handa, N, Yokoyama, S. | Deposit date: | 2012-04-21 | Release date: | 2013-05-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.464 Å) | Cite: | A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
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1AUO
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![BU of 1auo by Molmil](/molmil-images/mine/1auo) | CARBOXYLESTERASE FROM PSEUDOMONAS FLUORESCENS | Descriptor: | CARBOXYLESTERASE | Authors: | Kim, K.K, Song, H.K, Suh, S.W. | Deposit date: | 1997-09-01 | Release date: | 1998-03-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of carboxylesterase from Pseudomonas fluorescens, an alpha/beta hydrolase with broad substrate specificity. Structure, 5, 1997
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6RW1
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![BU of 6rw1 by Molmil](/molmil-images/mine/6rw1) | Crystal structure of hCA II in complex with Urea, N-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)-N'-(phenylmethyl)- | Descriptor: | 1-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-trien-4-yl]-3-(phenylmethyl)thiourea, Carbonic anhydrase 2, ZINC ION | Authors: | Di Fiore, A, De Simone, G. | Deposit date: | 2019-06-03 | Release date: | 2019-08-28 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity. J Enzyme Inhib Med Chem, 34, 2019
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5AE1
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![BU of 5ae1 by Molmil](/molmil-images/mine/5ae1) | Ether Lipid-Generating Enzyme AGPS in complex with inhibitor ZINC69435460 | Descriptor: | (3-(2-FLUOROPHENYL)-N-(1-(2-OXO-2,3-DIHYDRO-1H-BENZO[D]IMIDAZOL-5-YL)ETHYL)BUTANAMIDE), ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, ... | Authors: | Piano, V, Benjamin, D.I, Valente, S, Nenci, S, Marrocco, B, Mai, A, Aliverti, A, Nomura, D.K, Mattevi, A. | Deposit date: | 2015-08-25 | Release date: | 2015-09-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of Inhibitors for the Ether Lipid-Generating Enzyme Agps as Anti-Cancer Agents. Acs Chem.Biol., 10, 2015
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5WP9
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![BU of 5wp9 by Molmil](/molmil-images/mine/5wp9) | Structural Basis of Mitochondrial Receptor Binding and Constriction by Dynamin-Related Protein 1 | Descriptor: | Dynamin-1-like protein, MAGNESIUM ION, Mitochondrial dynamics protein MID49, ... | Authors: | Kalia, R, Wang, R.Y.R, Yusuf, A, Thomas, P.V, Agard, D.A, Shaw, J.M, Frost, A. | Deposit date: | 2017-08-03 | Release date: | 2018-06-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.22 Å) | Cite: | Structural basis of mitochondrial receptor binding and constriction by DRP1. Nature, 558, 2018
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1VFA
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2BNF
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![BU of 2bnf by Molmil](/molmil-images/mine/2bnf) | The structure of E. coli UMP kinase in complex with UTP | Descriptor: | GLYCEROL, URIDINE 5'-TRIPHOSPHATE, URIDYLATE KINASE | Authors: | Briozzo, P, Evrin, C, Meyer, P, Assairi, L, Joly, N, Barzu, O, Gilles, A.M. | Deposit date: | 2005-03-23 | Release date: | 2005-04-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of Escherichia Coli Ump Kinase Differs from that of Other Nucleoside Monophosphate Kinases and Sheds New Light on Enzyme Regulation. J.Biol.Chem., 280, 2005
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5AGD
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![BU of 5agd by Molmil](/molmil-images/mine/5agd) | An inactive (D125N) variant of the catalytic domain, BcGH76, of Bacillus circulans Aman6 in complex with alpha-1,6-mannopentaose | Descriptor: | ALPHA-1,6-MANNANASE, alpha-D-mannopyranose, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose | Authors: | Thompson, A.J, Speciale, G, Iglesias-Fernandez, J, Hakki, Z, Belz, T, Cartmell, A, Spears, R.J, Chandler, E, Temple, M.J, Stepper, J, Gilbert, H.J, Rovira, C, Williams, S.J, Davies, G.J. | Deposit date: | 2015-01-29 | Release date: | 2015-03-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Evidence for a Boat Conformation at the Transition State of Gh76 Alpha-1,6-Mannanases- Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism Angew.Chem.Int.Ed.Engl., 54, 2015
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1VSD
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![BU of 1vsd by Molmil](/molmil-images/mine/1vsd) | ASV INTEGRASE CORE DOMAIN WITH MG(II) COFACTOR AND HEPES LIGAND, HIGH MG CONCENTRATION FORM | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, INTEGRASE, MAGNESIUM ION | Authors: | Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A. | Deposit date: | 1995-11-29 | Release date: | 1996-04-03 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations. Structure, 4, 1996
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1N0W
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![BU of 1n0w by Molmil](/molmil-images/mine/1n0w) | Crystal structure of a RAD51-BRCA2 BRC repeat complex | Descriptor: | 1,2-ETHANEDIOL, ARTIFICIAL GLY-SER-MSE-GLY PEPTIDE, Breast cancer type 2 susceptibility protein, ... | Authors: | Pellegrini, L, Yu, D.S, Lo, T, Anand, S, Lee, M, Blundell, T.L, Venkitaraman, A.R. | Deposit date: | 2002-10-15 | Release date: | 2002-11-27 | Last modified: | 2020-01-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Insights into DNA recombination from the structure of a RAD51-BRCA2 complex Nature, 420, 2002
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4V2E
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![BU of 4v2e by Molmil](/molmil-images/mine/4v2e) | FLRT3 LRR domain | Descriptor: | FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 3 | Authors: | Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R. | Deposit date: | 2014-10-08 | Release date: | 2014-11-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development. Neuron, 84, 2014
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1N14
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![BU of 1n14 by Molmil](/molmil-images/mine/1n14) | Structure and Dynamics of Thioguanine-modified Duplex DNA in Comparison with Unmodified DNA; Structure of Unmodified Duplex DNA | Descriptor: | 5'-D(*GP*CP*TP*AP*AP*GP*GP*AP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*TP*CP*CP*TP*TP*AP*GP*C)-3' | Authors: | Somerville, L, Krynetski, E.Y, Krynetskaia, N.F, Beger, R.D, Zhang, W, Marhefka, C.A, Evans, W.E, Kriwacki, R.W. | Deposit date: | 2002-10-16 | Release date: | 2002-10-23 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure and dynamics of thioguanine-modified duplex DNA J.Biol.Chem., 278, 2003
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1VSC
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![BU of 1vsc by Molmil](/molmil-images/mine/1vsc) | VCAM-1 | Descriptor: | VASCULAR CELL ADHESION MOLECULE-1 | Authors: | Wang, J, Stehle, T, Osborn, L. | Deposit date: | 1995-04-27 | Release date: | 1996-06-20 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-alpha 4 integrin interaction. Proc.Natl.Acad.Sci.USA, 92, 1995
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