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3UCX
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BU of 3ucx by Molmil
The structure of a Short chain dehydrogenase from Mycobacterium smegmatis
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, PENTAETHYLENE GLYCOL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-10-27
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3UF5
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BU of 3uf5 by Molmil
Crystal structure of the mouse Colony-Stimulating Factor 1 (mCSF-1) cytokine
Descriptor: CALCIUM ION, Macrophage colony-stimulating factor 1
Authors:Elegheert, J, Bracke, N, Bekaert, A, Savvides, S.N.
Deposit date:2011-10-31
Release date:2012-08-22
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1
Nat.Struct.Mol.Biol., 19, 2012
3SFG
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BU of 3sfg by Molmil
crystal structure of murine norovirus RNA dependent RNA polymerase in complex with 2thiouridine(2TU)
Descriptor: 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, GLYCEROL, MAGNESIUM ION, ...
Authors:Kim, K.H, Alam, I.
Deposit date:2011-06-13
Release date:2012-05-09
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin.
Virology, 426, 2012
3UVE
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BU of 3uve by Molmil
Crystal structure of Carveol dehydrogenase ((+)-trans-carveol dehydrogenase) from Mycobacterium avium
Descriptor: 1,2-ETHANEDIOL, Carveol dehydrogenase ((+)-trans-carveol dehydrogenase), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-11-29
Release date:2011-12-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
2FFY
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BU of 2ffy by Molmil
AmpC beta-lactamase N289A mutant in complex with a boronic acid deacylation transition state analog compound SM3
Descriptor: (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION, ...
Authors:Chen, Y, Minasov, G, Roth, T.A, Prati, F, Shoichet, B.K.
Deposit date:2005-12-20
Release date:2006-03-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution
J.Am.Chem.Soc., 128, 2006
2E1Q
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BU of 2e1q by Molmil
Crystal Structure of Human Xanthine Oxidoreductase mutant, Glu803Val
Descriptor: 2-HYDROXYBENZOIC ACID, BICARBONATE ION, CALCIUM ION, ...
Authors:Yamaguchi, Y, Matsumura, T, Ichida, K, Okamoto, K, Nishino, T.
Deposit date:2006-10-27
Release date:2007-09-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate
J.Biochem.(Tokyo), 141, 2007
2EC5
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BU of 2ec5 by Molmil
Crystal structures reveal a thiol-protease like catalytic triad in the C-terminal region of Pasteurella multocida toxin
Descriptor: Dermonecrotic toxin
Authors:Kitadokoro, K, Horiguchi, Y, Kamitani, S.
Deposit date:2007-02-09
Release date:2007-03-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures reveal a thiol protease-like catalytic triad in the C-terminal region of Pasteurella multocida toxin
Proc.Natl.Acad.Sci.Usa, 104, 2007
3TZU
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Crystal structure of a glycine cleavage system H protein (GCVH) from Mycobacterium marinum
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-09-27
Release date:2011-10-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3U6E
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BU of 3u6e by Molmil
MutM set 1 TpGo
Descriptor: DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*AP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*TP*(8OG)P*GP*AP*(08Q)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ...
Authors:Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L.
Deposit date:2011-10-12
Release date:2012-04-25
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM.
J.Biol.Chem., 287, 2012
3TLF
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Crystal structure of an enoyl-CoA hydratase/isomerase from Mycobacterium paratuberculosis
Descriptor: 1,2-ETHANEDIOL, enoyl-CoA hydratase/isomerase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-08-29
Release date:2011-10-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
2F47
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Xray crystal structure of T4 lysozyme mutant L20/R63A liganded to methylguanidinium
Descriptor: 1-METHYLGUANIDINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W.
Deposit date:2005-11-22
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme.
Protein Sci., 15, 2006
3U6S
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BU of 3u6s by Molmil
MutM set 1 TpG
Descriptor: DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*AP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*TP*GP*GP*AP*(08Q)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ...
Authors:Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L.
Deposit date:2011-10-12
Release date:2012-04-25
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM.
J.Biol.Chem., 287, 2012
3U8B
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BU of 3u8b by Molmil
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Descriptor: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
Authors:Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F.
Deposit date:2011-10-16
Release date:2012-10-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
3U8J
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BU of 3u8j by Molmil
Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3531 (1-(pyridin-3-yl)-1,4-diazepane)
Descriptor: 1-(pyridin-3-yl)-1,4-diazepane, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine-binding protein, ...
Authors:Rohde, L.A.H, Ahring, P.K, Jensen, M.L, Nielsen, E.O, Peters, D, Helgstrand, C, Krintel, C, Harpsoe, K, Gajhede, M, Kastrup, J.S, Balle, T.
Deposit date:2011-10-17
Release date:2011-12-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha 4 beta 2 receptors: unique role of halogen bonding revealed.
J.Biol.Chem., 287, 2012
3UF2
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BU of 3uf2 by Molmil
Crystal structure of the human Colony-Stimulating Factor 1 (hCSF-1) cytokine
Descriptor: Macrophage colony-stimulating factor 1
Authors:Elegheert, J, Savvides, S.N.
Deposit date:2011-10-31
Release date:2012-08-22
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1
Nat.Struct.Mol.Biol., 19, 2012
3V4O
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BU of 3v4o by Molmil
Human MALT1 (caspase domain) in complex with an irreversible peptidic inhibitor
Descriptor: MALT1 Inhibitor, Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Authors:Renatus, M, Wiesmann, C.
Deposit date:2011-12-15
Release date:2012-03-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Determinants of MALT1 Protease Activity.
J.Mol.Biol., 419, 2012
2F2Q
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BU of 2f2q by Molmil
High resolution crystal structure of T4 lysozyme mutant L20R63/A liganded to guanidinium ion
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, GUANIDINE, ...
Authors:Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W.
Deposit date:2005-11-17
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme.
Protein Sci., 15, 2006
2F32
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BU of 2f32 by Molmil
Xray crystal structure of lysozyme mutant L20/R63A liganded to ethylguanidinium
Descriptor: BETA-MERCAPTOETHANOL, Lysozyme, N-ETHYLGUANIDINE
Authors:Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W.
Deposit date:2005-11-18
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme.
Protein Sci., 15, 2006
2FJU
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BU of 2fju by Molmil
Activated Rac1 bound to its effector phospholipase C beta 2
Descriptor: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CALCIUM ION, ...
Authors:Jezyk, M.R, Snyder, J.T, Harden, T.K, Sondek, J.
Deposit date:2006-01-03
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Rac1 bound to its effector phospholipase C-beta2.
Nat.Struct.Mol.Biol., 13, 2006
2D0D
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BU of 2d0d by Molmil
Crystal Structure of a Meta-cleavage Product Hydrolase (CumD) A129V Mutant
Descriptor: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, CHLORIDE ION, PHOSPHATE ION
Authors:Jun, S.Y, Fushinobu, S, Nojiri, H, Omori, T, Shoun, H, Wakagi, T.
Deposit date:2005-08-01
Release date:2006-06-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Improving the catalytic efficiency of a meta-cleavage product hydrolase (CumD) from Pseudomonas fluorescens IP01
Biochim.Biophys.Acta, 1764, 2006
3V4L
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BU of 3v4l by Molmil
Mouse MALT1(caspase-IG3 domains) in complex with a irreversible peptidic inhibitor
Descriptor: MALT1 Inhibitor, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog
Authors:Renatus, M, Wiesmann, C.
Deposit date:2011-12-15
Release date:2012-03-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural Determinants of MALT1 Protease Activity.
J.Mol.Biol., 419, 2012
3V55
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BU of 3v55 by Molmil
Human MALT1 (334-719) in its ligand free form
Descriptor: Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Authors:Renatus, M, Wiesmann, C.
Deposit date:2011-12-16
Release date:2012-03-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural Determinants of MALT1 Protease Activity.
J.Mol.Biol., 419, 2012
2CW2
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BU of 2cw2 by Molmil
Crystal structure of Superoxide dismutase from P. Marinus
Descriptor: FE (III) ION, superoxide dismutase 1
Authors:Asojo, O.A, Schott, E.J, Vasta, G.R, Silva, A.M.
Deposit date:2005-06-16
Release date:2006-07-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structures of PmSOD1 and PmSOD2, two superoxide dismutases from the protozoan parasite Perkinsus marinus
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2FPB
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BU of 2fpb by Molmil
Structure of Strictosidine Synthase, the Biosynthetic Entry to the Monoterpenoid Indole Alkaloid Family
Descriptor: 2-(1H-INDOL-3-YL)ETHANAMINE, Strictosidine Synthase
Authors:Panjikar, S.
Deposit date:2006-01-16
Release date:2006-05-23
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins
Plant Cell, 18, 2006
2FP8
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BU of 2fp8 by Molmil
Structure of Strictosidine Synthase, the Biosynthetic Entry to the Monoterpenoid Indole Alkaloid Family
Descriptor: Strictosidine synthase
Authors:Panjikar, S.
Deposit date:2006-01-16
Release date:2006-05-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of Rauvolfia serpentina strictosidine synthase is a novel six-bladed beta-propeller fold in plant proteins
Plant Cell, 18, 2006

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