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8BQS
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BU of 8bqs by Molmil
Cryo-EM structure of the I-II-III2-IV2 respiratory supercomplex from Tetrahymena thermophila
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
Authors:Muhleip, A, Kock Flygaard, R, Baradaran, R, Amunts, A.
Deposit date:2022-11-21
Release date:2023-08-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
To Be Published
8TID
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BU of 8tid by Molmil
Combined linker domain of N-DRC and associated proteins Tetrahymena
Descriptor: AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ...
Authors:Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H.
Deposit date:2023-07-19
Release date:2023-09-27
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
8TEK
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BU of 8tek by Molmil
Baseplate of Nexin-dynein regulatory complex from Tetrahymena thermophila
Descriptor: CFAP20, Cilia- and flagella-associated protein 91, Coiled-coil protein, ...
Authors:Ghanaeian, A.G, Black, C.S, Yang, S.K, Bui, K.H.
Deposit date:2023-07-06
Release date:2023-09-20
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
8TH8
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BU of 8th8 by Molmil
Linker domain of Nexin-dynein regulatory complex from Tetrahymena thermophila
Descriptor: AAA family ATPase CDC48 subfamily protein, Calmodulin 7-2, Coiled-coil domain-containing protein 153, ...
Authors:Ghanaeian, A.G, Bui, K.H.
Deposit date:2023-07-14
Release date:2023-09-20
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
1KLO
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BU of 1klo by Molmil
CRYSTAL STRUCTURE OF THREE CONSECUTIVE LAMININ-TYPE EPIDERMAL GROWTH FACTOR-LIKE (LE) MODULES OF LAMININ GAMMA1 CHAIN HARBORING THE NIDOGEN BINDING SITE
Descriptor: LAMININ
Authors:Stetefeld, J, Mayer, U, Timpl, R, Huber, R.
Deposit date:1996-02-02
Release date:1997-08-20
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of three consecutive laminin-type epidermal growth factor-like (LE) modules of laminin gamma1 chain harboring the nidogen binding site.
J.Mol.Biol., 257, 1996
6D6V
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BU of 6d6v by Molmil
CryoEM structure of Tetrahymena telomerase with telomeric DNA at 4.8 Angstrom resolution
Descriptor: DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3'), RNA (159-MER), Telomerase associated protein p65, ...
Authors:Jiang, J, Wang, Y, Susac, L, Chan, H, Basu, R, Zhou, Z.H, Feigon, J.
Deposit date:2018-04-22
Release date:2018-05-30
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of Telomerase with Telomeric DNA.
Cell, 173, 2018
8QA4
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BU of 8qa4 by Molmil
MTHFR + SAH symmetric dis-inhibited state
Descriptor: Methylenetetrahydrofolate reductase (NADPH), S-ADENOSYL-L-HOMOCYSTEINE
Authors:Blomgren, L.K.M, Yue, W.W, Froese, D.S, McCorvie, T.J.
Deposit date:2023-08-22
Release date:2023-11-08
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase.
Nat Commun, 15, 2024
5XAZ
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BU of 5xaz by Molmil
Crystal structure of full length native tylp, a tetr regulator from streptomyces fradiae
Descriptor: Gamma-butyrolactone receptor protein
Authors:Ray, S, Panjikar, S, Anand, R.
Deposit date:2017-03-15
Release date:2017-08-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional insights into the mode of DNA and ligand binding of the TetR family regulator TylP from Streptomyces fradiae
J. Biol. Chem., 292, 2017
5XAY
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BU of 5xay by Molmil
Crystal structure of full length tylp, a tetr regulator from streptomyces fradiae
Descriptor: Gamma-butyrolactone receptor protein
Authors:Ray, S, Panjikar, S, Anand, R.
Deposit date:2017-03-15
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Functional insights into the mode of DNA and ligand binding of the TetR family regulator TylP from Streptomyces fradiae
J. Biol. Chem., 292, 2017
3MQ7
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BU of 3mq7 by Molmil
Crystal Structure of Ectodomain Mutant of BST-2/Tetherin/CD317
Descriptor: Bone marrow stromal antigen 2, CALCIUM ION
Authors:Xiong, Y, Yang, H, Wang, J, Meng, W.
Deposit date:2010-04-27
Release date:2010-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural insight into the mechanisms of enveloped virus tethering by tetherin.
Proc.Natl.Acad.Sci.USA, 107, 2010
8D78
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BU of 8d78 by Molmil
Crystal structure of a Ba stabilized four-tetrad, parallel Tetrahymena thermophila telomeric G-quadruplex in complex with N-methyl mesoporphyrin IX
Descriptor: BARIUM ION, DNA (5'-D(*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*G)-3'), N-METHYLMESOPORPHYRIN
Authors:Chen, E.V, Beseiso, D, Yatsunyk, L.A.
Deposit date:2022-06-07
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Biophysical and structural characterization of telomeric G-quadruplexes from Tetrahymena thermophila in complex with N-Methyl Mesoporphyrin IX
To Be Published
8D79
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BU of 8d79 by Molmil
Crystal structure of a four-tetrad, parallel, and Na+ stabilized Tetrahymena thermophila telomeric G-quadruplex in complex with N-methyl mesoporphyrin IX
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3'), N-METHYLMESOPORPHYRIN, ...
Authors:Chen, E.V, Beseiso, D, Yatsunyk, L.A.
Deposit date:2022-06-07
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Biophysical and structural characterization of telomeric G-quadruplexes from Tetrahymena thermophila in complex with N-Methyl Mesoporphyrin IX
To Be Published
3LS5
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BU of 3ls5 by Molmil
Anti-tetrahydrocannabinol Fab Fragment, Free Form
Descriptor: Heavy chain of antibody Fab fragment, Light chain of antibody Fab fragment
Authors:Niemi, M.H, Rouvinen, J.
Deposit date:2010-02-12
Release date:2010-06-02
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural insight into the molecular recognition of a (-)-Delta9-tetrahydrocannabinol and the development of a sensitive, one-step, homogeneous immunocomplex-based assay for its detection
J.Mol.Biol., 400, 2010
3FK6
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BU of 3fk6 by Molmil
Crystal structure of TetR triple mutant (H64K, S135L, S138I)
Descriptor: Tetracycline repressor protein class B from transposon Tn10, Tetracycline repressor protein class D
Authors:Klieber, M.A, Scholz, O, Lochner, S, Gmeiner, P, Hillen, W, Muller, Y.A.
Deposit date:2008-12-16
Release date:2009-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural origins for selectivity and specificity in an engineered bacterial repressor-inducer pair.
Febs J., 276, 2009
8HME
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BU of 8hme by Molmil
head module state 1 of Tetrahymena IFT-A
Descriptor: Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ...
Authors:Ma, Y, Wu, J, Lei, M.
Deposit date:2022-12-03
Release date:2023-06-14
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
7NWD
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BU of 7nwd by Molmil
Three-quartet c-kit2 G-quadruplex stabilized by a pyrene conjugate
Descriptor: POTASSIUM ION, c-kit2_py1
Authors:Peterkova, K, Durnik, I, Marek, R, Plavec, J, Podbevsek, P.
Deposit date:2021-03-16
Release date:2021-08-04
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:c-kit2 G-quadruplex stabilized via a covalent probe: exploring G-quartet asymmetry.
Nucleic Acids Res., 49, 2021
3L93
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BU of 3l93 by Molmil
Phosphopantetheine adenylyltransferase from Yersinia pestis.
Descriptor: FORMIC ACID, Phosphopantetheine adenylyltransferase
Authors:Osipiuk, J, Maltseva, N, Makowska-grzyska, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-01-04
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:X-ray crystal structure of phosphopantetheine adenylyltransferase from Yersinia pestis.
To be Published
6QMH
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BU of 6qmh by Molmil
Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 3-(1H-indol-3-yl)propanoic acid at 1.6A resolution.
Descriptor: 5-[3-(1~{H}-indol-3-yl)propoxy]-1-phenyl-pyrazole-4-carboxylic acid, Phosphopantetheine adenylyltransferase
Authors:Blaszczyk, M, Blundell, T.L.
Deposit date:2019-02-07
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.837 Å)
Cite:Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors
To Be Published
6QMG
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BU of 6qmg by Molmil
Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis in complex with 5-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid at 1.8A resolution.
Descriptor: INDOLYLPROPIONIC ACID, Phosphopantetheine adenylyltransferase
Authors:Blaszczyk, M, Blundell, T.L.
Deposit date:2019-02-07
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Fragment linking applied to the discovery of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase inhibitors
To Be Published
7LHK
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BU of 7lhk by Molmil
High-Resolution Crystal Structure of a Lipin/Pah Phosphatidic Acid Phosphatase
Descriptor: CACODYLATE ION, Nuclear elongation and deformation protein
Authors:Khayyo, V.I, Airola, M.V.
Deposit date:2021-01-25
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:High-resolution structure of phosphatidic acid phosphohydrolase from Tetrahymena thermophila
To be published
5TCX
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BU of 5tcx by Molmil
Crystal structure of human tetraspanin CD81
Descriptor: CD81 antigen, CHOLESTEROL
Authors:Zimmerman, B, McMillan, B.J, Seegar, T.C.M, Kruse, A.C, Blacklow, S.C.
Deposit date:2016-09-16
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.955 Å)
Cite:Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket.
Cell, 167, 2016
3L92
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BU of 3l92 by Molmil
Phosphopantetheine adenylyltransferase from Yersinia pestis complexed with coenzyme A.
Descriptor: COENZYME A, Phosphopantetheine adenylyltransferase
Authors:Osipiuk, J, Maltseva, N, Makowska-grzyska, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-01-04
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:X-ray crystal structure of phosphopantetheine adenylyltransferase from Yersinia pestis.
To be Published
4R0N
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BU of 4r0n by Molmil
Hexagonal form of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis
Descriptor: Phosphopantetheine adenylyltransferase, SULFATE ION
Authors:Timofeev, V.I, Smirnova, E.A, Chupova, L.A, Esipov, R.S, Kuranova, I.P.
Deposit date:2014-08-01
Release date:2014-08-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hexagonal form of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis
TO BE PUBLISHED
3LCJ
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BU of 3lcj by Molmil
Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis complexed with CoA
Descriptor: COENZYME A, Phosphopantetheine adenylyltransferase
Authors:Timofeev, V.I, Smirnova, E.A, Chupova, L.A, Esipov, R.S, Kuranova, I.P.
Deposit date:2010-01-11
Release date:2010-07-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Preparation of the Crystal Complex of Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis with Coenzyme A and Investigation of Its Three-Dimensional Structure at 2.1-A frame Resolution
CRYSTALLOGRAPHY REPORTS, 55, 2010
3HY4
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BU of 3hy4 by Molmil
Structure of human MTHFS with N5-iminium phosphate
Descriptor: 5-formyltetrahydrofolate cyclo-ligase, MAGNESIUM ION, N-({trans-4-[({(2R,4R,4aS,6S,8aS)-2-amino-4-hydroxy-5-[(phosphonooxy)methyl]decahydropteridin-6-yl}methyl)amino]cyclohexyl}carbonyl)-L-glutamic acid, ...
Authors:Wu, D, Li, Y, Song, G, Cheng, C, Shaw, N, Liu, Z.-J.
Deposit date:2009-06-22
Release date:2009-07-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009

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