8D58
| Crystal structure of human METTL1-WDR4 complex | Descriptor: | CHLORIDE ION, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Raj, R, Babu, K, Nam, Y. | Deposit date: | 2022-06-04 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structures and mechanisms of tRNA methylation by METTL1-WDR4. Nature, 613, 2023
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7ORK
| La Crosse virus polymerase in transcription mode with cleaved capped RNA entering the polymerase active site | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (5'-D(*(GTG))-R(P*A)-3'), ... | Authors: | Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. | Deposit date: | 2021-06-06 | Release date: | 2022-02-16 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
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4WNL
| The X-ray structure of a RNA-binding protein complex | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, SULFATE ION, ... | Authors: | Singh, N, Blobel, G, Shi, H. | Deposit date: | 2014-10-13 | Release date: | 2014-12-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Hooking She3p onto She2p for myosin-mediated cytoplasmic mRNA transport. Proc.Natl.Acad.Sci.USA, 112, 2015
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6HA8
| Cryo-EM structure of the ABCF protein VmlR bound to the Bacillus subtilis ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Crowe-McAuliffe, C, Graf, M, Huter, P, Abdelshahid, M, Novacek, J, Wilson, D.N. | Deposit date: | 2018-08-07 | Release date: | 2018-08-29 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for antibiotic resistance mediated by theBacillus subtilisABCF ATPase VmlR. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8TVY
| Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) | Descriptor: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | Deposit date: | 2023-08-18 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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3L8U
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7V2Q
| T.thermophilus 30S ribosome with KsgA, class K6 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2N
| T.thermophilus 30S ribosome with KsgA, class K2 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2O
| T.thermophilus 30S ribosome with KsgA, class K4 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2M
| T.thermophilus 30S ribosome with KsgA, class K1k4 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2L
| T.thermophilus 30S ribosome with KsgA, class K1k2 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2P
| T.thermophilus 30S ribosome with KsgA, class K5 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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8PJ6
| Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3 (off-pathway) | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | Deposit date: | 2023-06-22 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
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7QCA
| Spraguea lophii ribosome | Descriptor: | 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ... | Authors: | Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. | Deposit date: | 2021-11-22 | Release date: | 2022-11-30 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state Nat Microbiol, 2023
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7SYK
| Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII) | Descriptor: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | Authors: | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2021-11-25 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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8BSJ
| Giardia Ribosome in PRE-T Classical State (C) | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | Deposit date: | 2022-11-25 | Release date: | 2023-03-22 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (6.49 Å) | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis. Nucleic Acids Res., 51, 2023
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8PJ3
| Structure of human 48S translation initiation complex upon transfer of initiator tRNA to eIF5B (48S-3) | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | Deposit date: | 2023-06-22 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
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8BTD
| Giardia Ribosome in PRE-T Hybrid State (D1) | Descriptor: | 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ... | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | Deposit date: | 2022-11-28 | Release date: | 2023-03-22 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis. Nucleic Acids Res., 51, 2023
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8BQX
| Yeast 80S ribosome in complex with Map1 (conformation 2) | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | Deposit date: | 2022-11-21 | Release date: | 2023-03-22 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains. Plos Biol., 21, 2023
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8BTR
| Giardia Ribosome in PRE-T Hybrid State (D2) | Descriptor: | 5.8S rRNA, 5S rRNA, Large Subunit rRNA, ... | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | Deposit date: | 2022-11-29 | Release date: | 2023-03-22 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis. Nucleic Acids Res., 51, 2023
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1N8R
| Structure of large ribosomal subunit in complex with virginiamycin M | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L13P, ... | Authors: | Hansen, J.L, Moore, P.B, Steitz, T.A. | Deposit date: | 2002-11-21 | Release date: | 2003-07-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of
the Large Ribosomal Subunit J.Mol.Biol., 330, 2003
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6YBW
| Structure of a human 48S translational initiation complex - 40S body | Descriptor: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | Authors: | Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. | Deposit date: | 2020-03-18 | Release date: | 2020-09-16 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of a human 48Stranslational initiation complex. Science, 369, 2020
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8EMM
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1NJI
| Structure of chloramphenicol bound to the 50S ribosomal subunit | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L13P, ... | Authors: | Hansen, J.L, Moore, P.B, Steitz, T.A. | Deposit date: | 2002-12-31 | Release date: | 2003-07-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of
the Large Ribosomal Subunit J.Mol.Biol., 330, 2003
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8IPA
| Wheat 80S ribosome stalled on AUG-Stop boron dependently with cycloheximide | Descriptor: | 18S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 40S ribosomal protein eL8, ... | Authors: | Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. | Deposit date: | 2023-03-14 | Release date: | 2024-02-21 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1. Nat.Chem.Biol., 20, 2024
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