6WU9
| |
8WB0
| De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt downstream of TSS | Descriptor: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-08 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
|
|
8WAU
| De novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt downstream of TSS | Descriptor: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-08 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
|
|
5FKI
| Pseudorabies virus (PrV) nuclear egress complex proteins fitted as a hexameric lattice into a sub-tomogram average derived from focused- ion beam milled lamellae electron cryo-microscopic data | Descriptor: | CHLORIDE ION, UL31, UL34 protein, ... | Authors: | Hagen, C, Dent, K.C, Zeev Ben Mordehai, T, Vasishtan, D, Antonin, W, Mettenleiter, T.C, Gruenewald, K. | Deposit date: | 2015-10-16 | Release date: | 2016-03-16 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (35 Å) | Cite: | Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights Into Inner Nuclear Membrane Remodelling Cell Rep., 13, 2015
|
|
6NSH
| Modified ASL proline bound to Thermus thermophilus 70S (near-cognate) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M. | Deposit date: | 2019-01-24 | Release date: | 2020-10-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.397 Å) | Cite: | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife, 9, 2020
|
|
6XIR
| Cryo-EM Structure of K63 Ubiquitinated Yeast Translocating Ribosome under Oxidative Stress | Descriptor: | 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Zhou, Y, Bartesaghi, A, Silva, G.M. | Deposit date: | 2020-06-21 | Release date: | 2020-08-26 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6XQE
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S. | Deposit date: | 2020-07-09 | Release date: | 2020-08-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6CFJ
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with histidyl-CAM and bound to mRNA and A-, P-, and E-site tRNAs at 2.8A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Tereshchenkov, A.G, Dobosz-Bartoszek, M, Osterman, I.A, Marks, J, Sergeeva, V.A, Kasatsky, P, Komarova, E.S, Stavrianidi, A.N, Rodin, I.A, Konevega, A.L, Sergiev, P.V, Sumbatyan, N.V, Mankin, A.S, Bogdanov, A.A, Polikanov, Y.S. | Deposit date: | 2018-02-15 | Release date: | 2018-03-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome. J. Mol. Biol., 430, 2018
|
|
6XRE
| Structure of the p53/RNA polymerase II assembly | Descriptor: | Cellular tumor antigen p53, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | Liou, S.-H, Singh, S, Singer, R.H, Coleman, R.A, Liu, W. | Deposit date: | 2020-07-12 | Release date: | 2021-03-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structure of the p53/RNA polymerase II assembly. Commun Biol, 4, 2021
|
|
5FJ1
| |
8UKT
| RNA polymerase II elongation complex with Fapy-dG lesion with AMP added | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Hou, P, Oh, J, Wang, D. | Deposit date: | 2023-10-15 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
|
|
8UKS
| RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | Authors: | Hou, P, Oh, J, Wang, D. | Deposit date: | 2023-10-15 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
|
|
6WQQ
| |
5FCJ
| Structure of the anisomycin-containing uL3 W255C mutant 80S yeast ribosome | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M. | Deposit date: | 2015-12-15 | Release date: | 2016-05-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency. J.Mol.Biol., 428, 2016
|
|
6XR2
| |
7N56
| |
6ECJ
| |
7EGB
| TFIID-based holo PIC on SCP promoter | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
|
|
5HCQ
| Crystal structure of antimicrobial peptide Oncocin d15-19 bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. | Deposit date: | 2016-01-04 | Release date: | 2016-04-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
|
|
6YS3
| Cryo-EM structure of the 50S ribosomal subunit at 2.58 Angstroms with modeled GBC SecM peptide | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Schulte, L, Reitz, J, Kudlinzki, D, Hodirnau, V.V, Frangakis, A, Schwalbe, H. | Deposit date: | 2020-04-20 | Release date: | 2020-09-30 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Cryo-EM structure of the 50S ribosomal subunit at 2.58 Angstroms with modeled GBC SecM peptide Nat Commun, 2020
|
|
7EGC
| p53-bound TFIID-based holo PIC on HDM2 promoter | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
|
|
5I2D
| Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo | Descriptor: | DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Feng, Y, Zhang, Y, Ebright, R.H. | Deposit date: | 2016-02-08 | Release date: | 2016-06-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4.405 Å) | Cite: | Structural basis of transcription activation. Science, 352, 2016
|
|
5OKZ
| Crystal Strucrure of the Mpp6 Exosome complex | Descriptor: | CHLORIDE ION, Exosome complex component CSL4, Exosome complex component MTR3, ... | Authors: | Falk, S, Ebert, J, Conti, E. | Deposit date: | 2017-07-26 | Release date: | 2017-08-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.200039 Å) | Cite: | Mpp6 Incorporation in the Nuclear Exosome Contributes to RNA Channeling through the Mtr4 Helicase. Cell Rep, 20, 2017
|
|
8WAV
| De novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt downstream of TSS | Descriptor: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-08 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
|
|
8WAZ
| De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt downstream of TSS | Descriptor: | Alpha-amanitin, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-08 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
|
|