PDB: 82 resultsInfo pagesStatus searchChemie searchBIRD

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7KX9	Cryo-EM structure of Ephydatia fluviatilis PiwiA-piRNA-target complex Descriptor: MAGNESIUM ION, Piwi-A, RNA (5'-R(P*UP*CP*UP*CP*UP*UP*GP*AP*GP*UP*UP*GP*GP*AP*CP*AP*AP*AP*UP*GP*GP*CP*AP*(OMG))-3'), ... Authors: Anzelon, T.A, Chowdhury, S, Lander, G.C, MacRae, I.J. Deposit date: 2020-12-03 Release date: 2021-07-14 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis for piRNA targeting. Nature, 597, 2021
6MFR	Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3) Descriptor: PHENOL, PHOSPHATE ION, Protein argonaute-2, ... Authors: Sheu-Gruttadauria, J, MacRae, I.J. Deposit date: 2018-09-12 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
2YHB	Crystal Structure of the N. crassa QDE-2 AGO MID-PIWI Domains Descriptor: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION Authors: Boland, A, Weichenrieder, O. Deposit date: 2011-04-27 Release date: 2011-06-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.65 Å) Cite: Crystal Structure of the Mid-Piwi Lobe of a Eukaryotic Argonaute Protein Proc.Natl.Acad.Sci.USA, 108, 2011
7SWF	Cryo-EM structure of Arabidopsis Ago10-guide-target RNA complex in a central duplex conformation Descriptor: MAGNESIUM ION, Protein argonaute 10, RNA (5'-R(P*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*A)-3'), ... Authors: Xiao, Y, MacRae, I.J. Deposit date: 2021-11-19 Release date: 2022-08-03 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: The molecular mechanism of microRNA duplex selectivity of Arabidopsis ARGONAUTE10. Nucleic Acids Res., 50, 2022
7SWQ	Cryo-EM structure of Arabidopsis Ago10-guide-target RNA complex in a bent duplex conformation Descriptor: MAGNESIUM ION, Protein argonaute 10, RNA (5'-R(P*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), ... Authors: Xiao, Y, MacRae, I.J. Deposit date: 2021-11-21 Release date: 2022-11-23 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: Structural basis for RNA slicing by a plant Argonaute. Nat.Struct.Mol.Biol., 30, 2023
7KX7	Cryo-EM structure of Ephydatia fluviatilis PiwiA-piRNA complex Descriptor: MAGNESIUM ION, Piwi-A, RNA (5'-R(P*UP*CP*UP*CP*AP*GP*(OMC))-3') Authors: Anzelon, T.A, Chowdhury, S, Lander, G.C, MacRae, I.J. Deposit date: 2020-12-03 Release date: 2021-07-14 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural basis for piRNA targeting. Nature, 597, 2021
6NIT	Human Argonaute2-miR-122 bound to a target RNA with four central mismatches (bu4) Descriptor: Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*CP*CP*AP*UP*CP*CP*AP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3') Authors: Sheu-Gruttadauria, J, MacRae, I.J. Deposit date: 2018-12-31 Release date: 2019-08-07 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019

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