3N2S
| Structure of NfrA1 nitroreductase from B. subtilis | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, NADPH-dependent nitro/flavin reductase | Authors: | Morera, S, Gueguen-Chaignon, V, Meyer, P, Cortial, S, Ouazzani, J. | Deposit date: | 2010-05-19 | Release date: | 2010-09-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | NADH oxidase activity of Bacillus subtilis nitroreductase NfrA1: insight into its biological role. Febs Lett., 584, 2010
|
|
5UU6
| The crystal structure of nitroreductase A from Vibrio parahaemolyticus RIMD 2210633 | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Tan, K, Zhou, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-02-16 | Release date: | 2017-03-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The crystal structure of nitroreductase A from Vibrio parahaemolyticus RIMD 2210633 To Be Published
|
|
7S1A
| Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae Rd KW20 | Descriptor: | ACETIC ACID, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | Authors: | Maltseva, N, Kim, Y, Endres, M, Crofts, T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-09-01 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens. Microbiol Spectr, 10, 2022
|
|
7TMF
| |
8CJ0
| E. coli NfsB-T41Q/N71S/F124T/M127V mutant bound to nicotinate | Descriptor: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... | Authors: | White, S.A, Hyde, E.I, Day, M.A. | Deposit date: | 2023-02-11 | Release date: | 2023-04-19 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
|
|
3EOF
| |
1IDT
| STRUCTURAL STUDIES ON A PRODRUG-ACTIVATING SYSTEM-CB1954 AND FMN-DEPENDENT NITROREDUCTASE | Descriptor: | 5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE, FLAVIN MONONUCLEOTIDE, MINOR FMN-DEPENDENT NITROREDUCTASE | Authors: | Johansson, E, Parkinson, G.N, Denny, W.A, Neidle, S. | Deposit date: | 2001-04-05 | Release date: | 2003-09-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form. J.Med.Chem., 46, 2003
|
|
3HJ9
| |
8Q5G
| |
7VQK
| |
7JH4
| Crystal structure of NAD(P)H-flavin oxidoreductase (NfoR) from S. aureus complexed with reduced FMN and NAD+ | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, NAD(P)H-dependent oxidoreductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Zheng, Y, O'Neill, A.G, Beaupre, B.A, Liu, D, Moran, G.R. | Deposit date: | 2020-07-20 | Release date: | 2020-09-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | NfoR: Chromate Reductase or Flavin Mononucleotide Reductase? Appl.Environ.Microbiol., 86, 2020
|
|
3GB5
| Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) bound to FMN | Descriptor: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Iodotyrosine dehalogenase 1, ... | Authors: | Thomas, S.R, McTamney, P.M, Adler, J.M, LaRonde-LeBlanc, N, Rokita, S.E. | Deposit date: | 2009-02-18 | Release date: | 2009-05-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands. J.Biol.Chem., 284, 2009
|
|
3GBH
| |
1YLU
| The structure of E. coli nitroreductase with bound acetate, crystal form 2 | Descriptor: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | Authors: | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | Deposit date: | 2005-01-19 | Release date: | 2005-02-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme. J.Biol.Chem., 280, 2005
|
|
1OOQ
| Nitroreductase from e-coli in complex with the inhibitor dicoumarol | Descriptor: | BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE], FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | Authors: | Johansson, E, Parkinson, G.N, Denny, W.A, Neidle, S. | Deposit date: | 2003-03-04 | Release date: | 2003-04-02 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form J.Med.Chem., 46, 2003
|
|
3QDL
| Crystal structure of RdxA from Helicobacter pyroli | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, Oxygen-insensitive NADPH nitroreductase | Authors: | Rojas, A.L, Martinez-Julvez, M, Olekhnovich, I.N, Hoffman, P.S, Sancho, J. | Deposit date: | 2011-01-18 | Release date: | 2012-01-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of RdxA--an oxygen-insensitive nitroreductase essential for metronidazole activation in Helicobacter pylori. Febs J., 279, 2012
|
|
1OO6
| Nitroreductase from e-coli in complex with the dinitrobenzamide prodrug SN23862 | Descriptor: | 5-[BIS-2(CHLORO-ETHYL)-AMINO]-2,4-DINTRO-BENZAMIDE, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | Authors: | Johansson, E, Parkinson, G.N, Denny, W.A, Neidle, S. | Deposit date: | 2003-03-03 | Release date: | 2003-04-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form J.Med.Chem., 46, 2003
|
|
1V5Z
| Binding of coumarins to NAD(P)H:FMN oxidoreductase | Descriptor: | (2E)-3-(2-HYDROXYPHENYL)ACRYLIC ACID, FLAVIN MONONUCLEOTIDE, Major NAD(P)H-flavin oxidoreductase | Authors: | Kobori, T, Koike, H, Sasaki, H, Zenno, S, Saigo, K, Tanokura, M. | Deposit date: | 2003-11-26 | Release date: | 2005-03-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of coumarins to NAD(P)H:FMN oxidoreductase To be Published
|
|
3BM1
| |
3X22
| Crystal structure of Escherichia coli nitroreductase NfsB mutant N71S/F123A/F124W | Descriptor: | FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | Authors: | Bai, J, Yang, J, Zhou, Y, Yang, Q. | Deposit date: | 2014-12-06 | Release date: | 2015-11-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural basis of Escherichia coli nitroreductase NfsB triple mutants engineered for improved activity and regioselectivity toward the prodrug CB1954 PROCESS BIOCHEM, 50, 2015
|
|
7DP1
| |
4QLY
| Crystal structure of CLA-ER, a novel enone reductase catalyzing a key step of a gut-bacterial fatty acid saturation metabolism, biohydrogenation | Descriptor: | Enone reductase CLA-ER, FLAVIN MONONUCLEOTIDE | Authors: | Hou, F, Miyakawa, T, Tanokura, M. | Deposit date: | 2014-06-13 | Release date: | 2015-02-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.005 Å) | Cite: | Structure and reaction mechanism of a novel enone reductase. Febs J., 282, 2015
|
|
4XOQ
| F420 complex of coenzyme F420:L-glutamate ligase (FbiB) from Mycobacterium tuberculosis (C-terminal domain) | Descriptor: | COENZYME F420, Coenzyme F420:L-glutamate ligase, SULFATE ION | Authors: | Rehan, A.M, Bashiri, G, Baker, H.M, Baker, E.N, Squire, C.J. | Deposit date: | 2015-01-16 | Release date: | 2016-02-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
|
|
2B67
| Crystal structure of the Nitroreductase Family Protein from Streptococcus pneumoniae TIGR4 | Descriptor: | ACETIC ACID, COG0778: Nitroreductase, FLAVIN MONONUCLEOTIDE | Authors: | Kim, Y, Volkart, L, Abdullah, J, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-09-30 | Release date: | 2005-11-15 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal Structure of the Nitroreductase Family Protein from Streptococcus pneumoniae TIGR4 To be Published
|
|
1DS7
| |