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3I97
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B1 domain of human Neuropilin-1 bound with small molecule EG00229
Descriptor: (S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)thiophene-2-carboxamido)-5-guanidinopentanoic acid, GLYCEROL, Neuropilin-1
Authors:Allerston, C.K, Djordjevic, S.
Deposit date:2009-07-10
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction.
J.Med.Chem., 53, 2010
3HNY
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Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
Descriptor: Coagulation factor VIII
Authors:Liu, Z, Yuan, C.
Deposit date:2009-06-01
Release date:2010-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding.
J.Biol.Chem., 285, 2010
3JD6
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BU of 3jd6 by Molmil
Double octamer structure of retinoschisin, a cell-cell adhesion protein of the retina
Descriptor: Retinoschisin
Authors:Tolun, G, Vijayasarathy, C, Huang, R, Zeng, Y, Li, Y, Steven, A.C, Sieving, P.A, Heymann, J.B.
Deposit date:2016-04-12
Release date:2016-05-11
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Paired octamer rings of retinoschisin suggest a junctional model for cell-cell adhesion in the retina.
Proc.Natl.Acad.Sci.USA, 113, 2016
3HNB
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Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
Descriptor: (2R)-1-(2,4-dichlorophenoxy)-3-[(2E)-2-imino-3-(2-piperidin-1-ylethyl)-2,3-dihydro-1H-benzimidazol-1-yl]propan-2-ol, Coagulation factor VIII
Authors:Liu, Z, Yuan, C.
Deposit date:2009-05-31
Release date:2010-01-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding.
J.Biol.Chem., 285, 2010
4AAX
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CpGH89CBM32-5, from Clostridium perfringens, in complex with N- acetylgalactosamine
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, ALPHA-N-ACETYLGLUCOSAMINIDASE, CALCIUM ION, ...
Authors:Ficko-Blean, E, Stuart, C.P, Suits, M.D, Cid, M, Tessier, M, Woods, R.J, Boraston, A.B.
Deposit date:2011-12-05
Release date:2012-04-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Carbohydrate Recognition by an Architecturally Complex Alpha-N-Acetylglucosaminidase from Clostridium Perfringens.
Plos One, 7, 2012
4A42
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CpGH89CBM32-6 produced by Clostridium perfringens
Descriptor: ALPHA-N-ACETYLGLUCOSAMINIDASE FAMILY PROTEIN, CALCIUM ION
Authors:Ficko-Blean, E, Stuart, C.P, Suits, M.D, Cid, M, Tessier, M, Woods, R.J, Boraston, A.B.
Deposit date:2011-10-06
Release date:2012-04-04
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Carbohydrate Recognition by an Architecturally Complex Alpha-N-Acetylglucosaminidase from Clostridium Perfringens.
Plos One, 7, 2012
4A45
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CpGH89CBM32-5, from Clostridium perfringens, in complex with GalNAc- beta-1,3-galactose
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-beta-D-galactopyranose, ALPHA-N-ACETYLGLUCOSAMINIDASE FAMILY PROTEIN, CALCIUM ION, ...
Authors:Ficko-Blean, E, Stuart, C.P, Suits, M.D, Cid, M, Tessier, M, Woods, R.J, Boraston, A.B.
Deposit date:2011-10-06
Release date:2012-04-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Carbohydrate Recognition by an Architecturally Complex Alpha-N-Acetylglucosaminidase from Clostridium Perfringens.
Plos One, 7, 2012
4A41
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CpGH89CBM32-5, from Clostridium perfringens, in complex with galactose
Descriptor: ALPHA-N-ACETYLGLUCOSAMINIDASE FAMILY PROTEIN, CALCIUM ION, SODIUM ION, ...
Authors:Ficko-Blean, E, Stuart, C.P, Suits, M.D, Cid, M, Tessier, M, Woods, R.J, Boraston, A.B.
Deposit date:2011-10-06
Release date:2012-04-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Carbohydrate Recognition by an Architecturally Complex Alpha-N-Acetylglucosaminidase from Clostridium Perfringens.
Plos One, 7, 2012
4A44
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BU of 4a44 by Molmil
CpGH89CBM32-5, from Clostridium perfringens, in complex with the Tn Antigen
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Alpha-N-acetylglucosaminidase, CALCIUM ION, ...
Authors:Ficko-Blean, E, Stuart, C.P, Suits, M.D, Cid, M, Tessier, M, Woods, R.J, Boraston, A.B.
Deposit date:2011-10-06
Release date:2012-04-04
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Carbohydrate Recognition by an Architecturally Complex Alpha-N-Acetylglucosaminidase from Clostridium Perfringens.
Plos One, 7, 2012
7JJC
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BU of 7jjc by Molmil
Crystal structure of neuropilin-1 b1 domain in complex with SARS-CoV-2 S1 C-end rule (CendR) peptide
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Neuropilin-1, ...
Authors:Chen, K.-E, Collins, B.M.
Deposit date:2020-07-25
Release date:2020-10-28
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Neuropilin-1 is a host factor for SARS-CoV-2 infection.
Science, 370, 2020
7JNB
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BU of 7jnb by Molmil
The structure of CBM32-1 and CBM32-2 domains from Clostridium perfringens ZmpB in complex with GalNAc
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, F5/8 type C domain protein, ...
Authors:Pluvinage, B, Boraston, A.B.
Deposit date:2020-08-04
Release date:2021-02-03
Last modified:2021-08-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Architecturally complex O -glycopeptidases are customized for mucin recognition and hydrolysis.
Proc.Natl.Acad.Sci.USA, 118, 2021
7JND
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BU of 7jnd by Molmil
The structure of CBM32-1 and CBM32-2 domains from Clostridium perfringens ZmpB
Descriptor: CALCIUM ION, F5/8 type C domain protein, GLYCEROL
Authors:Pluvinage, B, Boraston, A.B.
Deposit date:2020-08-04
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Architecturally complex O -glycopeptidases are customized for mucin recognition and hydrolysis.
Proc.Natl.Acad.Sci.USA, 118, 2021
7JNF
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BU of 7jnf by Molmil
The structure of CBM32-1 and CBM32-2 domains from Clostridium perfringens ZmpB in complex with GalNAc
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, F5/8 type C domain protein, ...
Authors:Pluvinage, B, Boraston, A.B.
Deposit date:2020-08-04
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Architecturally complex O -glycopeptidases are customized for mucin recognition and hydrolysis.
Proc.Natl.Acad.Sci.USA, 118, 2021
2QQJ
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BU of 2qqj by Molmil
Crystal Structure of the b1b2 Domains from Human Neuropilin-2
Descriptor: GLYCEROL, Neuropilin-2
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2007-07-26
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2RV9
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BU of 2rv9 by Molmil
Solution structure of chitosan-binding module 1 derived from chitosanase/glucanase from Paenibacillus sp. IK-5
Descriptor: Glucanase
Authors:Shinya, S, Nishimura, S, Fukamizo, T.
Deposit date:2015-05-12
Release date:2016-04-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Mechanism of chitosan recognition by CBM32 carbohydrate-binding modules from a Paenibacillus sp. IK-5 chitosanase/glucanase.
Biochem.J., 473, 2016
2RVA
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BU of 2rva by Molmil
Solution structure of chitosan-binding module 2 derived from chitosanase/glucanase from Paenibacillus sp. IK-5
Descriptor: Glucanase
Authors:Shinya, S, Nishimura, S, Fukamizo, T.
Deposit date:2015-05-13
Release date:2016-04-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Mechanism of chitosan recognition by CBM32 carbohydrate-binding modules from a Paenibacillus sp. IK-5 chitosanase/glucanase.
Biochem.J., 473, 2016
2W1Q
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BU of 2w1q by Molmil
Unique ligand binding specificity for a family 32 Carbohydrate- Binding Module from the Mu toxin produced by Clostridium perfringens
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, HYALURONOGLUCOSAMINIDASE, ...
Authors:Ficko-Blean, E, Boraston, A.B.
Deposit date:2008-10-20
Release date:2009-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:N-Acetylglucosamine Recognition by a Family 32 Carbohydrate-Binding Module from Clostridium Perfringens Nagh.
J.Mol.Biol., 390, 2009
2W1U
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BU of 2w1u by Molmil
A family 32 carbohydrate-binding module, from the Mu toxin produced by Clostridium perfringens, in complex with beta-D-glcNAc-beta(1,3) galNAc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ACETATE ION, ...
Authors:Ficko-Blean, E, Boraston, A.B.
Deposit date:2008-10-20
Release date:2009-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-Acetylglucosamine Recognition by a Family 32 Carbohydrate-Binding Module from Clostridium Perfringens Nagh.
J.Mol.Biol., 390, 2009
2V72
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The structure of the family 32 CBM from C. perfringens NanJ in complex with galactose
Descriptor: CALCIUM ION, EXO-ALPHA-SIALIDASE, beta-D-galactopyranose
Authors:Boraston, A.B, Ficko-Blean, E, Healey, M.
Deposit date:2007-07-25
Release date:2007-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Carbohydrate Recognition by a Large Sialidase Toxin from Clostridium Perfringens.
Biochemistry, 46, 2007
2WDB
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BU of 2wdb by Molmil
A family 32 carbohydrate-binding module, from the Mu toxin produced by Clostridium perfringens, in complex with beta-D-glcNAc-beta(1,2) mannose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, CALCIUM ION, HYALURONOGLUCOSAMINIDASE
Authors:Ficko-Blean, E, Boraston, A.B.
Deposit date:2009-03-23
Release date:2009-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:N-Acetylglucosamine Recognition by a Family 32 Carbohydrate-Binding Module from Clostridium Perfringens Nagh.
J.Mol.Biol., 390, 2009
2W1S
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BU of 2w1s by Molmil
Unique ligand binding specificity of a family 32 Carbohydrate-Binding Module from the Mu toxin produced by Clostridium perfringens
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, HYALURONOGLUCOSAMINIDASE, ...
Authors:Ficko-Blean, E, Boraston, A.B.
Deposit date:2008-10-20
Release date:2009-05-05
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:N-Acetylglucosamine Recognition by a Family 32 Carbohydrate-Binding Module from Clostridium Perfringens Nagh.
J.Mol.Biol., 390, 2009
2WUH
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BU of 2wuh by Molmil
Crystal structure of the DDR2 discoidin domain bound to a triple- helical collagen peptide
Descriptor: COLLAGEN PEPTIDE, DISCOIDIN DOMAIN RECEPTOR 2
Authors:Carafoli, F, Bihan, D, Stathopoulos, S, Konitsiotis, A.D, Kvansakul, M, Farndale, R.W, Leitinger, B, Hohenester, E.
Deposit date:2009-10-05
Release date:2009-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic Insight Into Collagen Recognition by Discoidin Domain Receptor 2
Structure, 17, 2009
7NSN
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BU of 7nsn by Molmil
Multi-domain GH92 alpha-1,2-mannosidase from Neobacillus novalis: mannoimidazole complex
Descriptor: (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
Authors:Kolaczkowski, B.M, Moroz, O.V, Blagova, E, Davies, G.J, Wilson, K.S, Moeler, M.S, Meyer, A.S, Westh, P, Jensen, K, Krogh, K.B.R.M.
Deposit date:2021-03-08
Release date:2022-09-21
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural and functional characterization of a multi-domain GH92 alpha-1,2-mannosidase from Neobacillus novalis.
Acta Crystallogr D Struct Biol, 79, 2023
8FDG
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BU of 8fdg by Molmil
Cryo-EM structure of coagulation factor V short
Descriptor: Coagulation factor V
Authors:Mohammed, B.M, Pelc, L.A, Rau, M.J, Di Cera, E.
Deposit date:2022-12-03
Release date:2023-03-15
Last modified:2023-07-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of coagulation factor V short.
Blood, 141, 2023
8C5G
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BU of 8c5g by Molmil
Structure of human Neuropilin-1 b1b2 domains in complex with Chlorotoxin (Leiurus quinquestriatus)
Descriptor: Chlorotoxin, Neuropilin-1
Authors:Boros, E, Ecsedi, P, Szakacs, D, Nyitray, L.
Deposit date:2023-01-09
Release date:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of human Neuropilin-1 b1b2 domains in complex with Chlorotoxin (Leiurus quinquestriatus)
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