PDB: 394 resultsInfo pagesStatus searchChemie searchBIRD

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2R0J	Crystal structure of the putative ubiquitin conjugating enzyme, PFE1350c, from Plasmodium falciparum Descriptor: Ubiquitin carrier protein Authors: Wernimont, A.K, Lew, J, Lin, Y.H, Hassanali, A, Kozieradzki, I, Zhao, Y, Schapira, M, Bochkarev, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) Deposit date: 2007-08-20 Release date: 2007-09-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure of the putative ubiquitin conjugating enzyme, PFE1350c, from Plasmodium falciparum. To be Published
1Y6L	Human ubiquitin conjugating enzyme E2E2 Descriptor: Ubiquitin-conjugating enzyme E2E2 Authors: Walker, J.R, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Bochkarev, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2004-12-06 Release date: 2005-01-11 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
1J7D	Crystal Structure of hMms2-hUbc13 Descriptor: MMS2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA Authors: Moraes, T.F, Edwards, R.A, McKenna, S, Pashushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J. Deposit date: 2001-05-16 Release date: 2001-08-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13. Nat.Struct.Biol., 8, 2001
4JUE	Crystal structure of Plasmodium falciparum ubiquitin conjugating enzyme UBC9 Descriptor: Ubiquitin conjugating enzyme UBC9 Authors: Reiter, K.H, Boucher, L.E, Bosch, J, Matunis, J.M. Deposit date: 2013-03-24 Release date: 2013-08-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.851 Å) Cite: Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum. J.Biol.Chem., 288, 2013
2FO3	Plasmodium vivax ubiquitin conjugating enzyme E2 Descriptor: Ubiquitin-conjugating enzyme Authors: Dong, A, Zhao, Y, Lew, J, Kozieradski, I, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Bochkarev, A, Qiu, W, Structural Genomics Consortium (SGC) Deposit date: 2006-01-12 Release date: 2006-01-31 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
3E46	Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington interacting protein 2) M172A mutant Descriptor: CALCIUM ION, Ubiquitin-conjugating enzyme E2-25 kDa Authors: Hughes, R.C, Wilson, R.C, Flatt, J.W, Meehan, E.J, Ng, J.D, Twigg, P.D. Deposit date: 2008-08-09 Release date: 2008-08-26 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2). Acta Crystallogr.,Sect.F, 65, 2009
4Q5E	Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate Descriptor: Polyubiquitin, Protein kinase OspG, Ubiquitin-conjugating enzyme E2 L3 Authors: Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2014-04-16 Release date: 2014-07-02 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (1.869 Å) Cite: Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure, 22, 2014
2EKE	Structure of a SUMO-binding-motif mimic bound to Smt3p-Ubc9p: conservation of a noncovalent Ubiquitin-like protein-E2 complex as a platform for selective interactions within a SUMO pathway Descriptor: SUMO-conjugating enzyme UBC9, Ubiquitin-like protein SMT3 Authors: Duda, D.M, Schulman, B.A. Deposit date: 2007-03-23 Release date: 2007-05-29 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of a SUMO-binding-motif Mimic Bound to Smt3p-Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein-E2 Complex as a Platform for Selective Interactions within a SUMO Pathway J.Mol.Biol., 369, 2007
2PWQ	Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii Descriptor: Ubiquitin conjugating enzyme Authors: Qiu, W, Dong, A, Hassanali, A, Lin, L, Brokx, S, Altamentova, S, Hills, T, Lew, J, Ravichandran, M, Kozieradzki, I, Zhao, Y, Schapira, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) Deposit date: 2007-05-11 Release date: 2007-05-22 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii. To be Published
3RCZ	Rad60 SLD2 Ubc9 Complex Descriptor: DNA repair protein rad60, SUMO-conjugating enzyme ubc9 Authors: Perry, J.J.P, Arvai, A.S, Tainer, J.A. Deposit date: 2011-03-31 Release date: 2011-04-27 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes. Mol.Cell.Biol., 31, 2011
6SYF	Human Ubc9 with covalent isopeptide ligand Descriptor: ACE-ILE-LYS-GLN-GLU, ACE-LEU-ARG-LEU-ARG-GLY-CYS, SUMO-conjugating enzyme UBC9 Authors: Hofmann, R, Akimoto, G, Wucherpfennig, T.G, Zeymer, C, Bode, J.W. Deposit date: 2019-09-27 Release date: 2020-08-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins. Nat.Chem., 12, 2020
1FZY	CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE UBIQUITIN CONJUGATING ENZYME 1 Descriptor: UBIQUITIN-CONJUGATING ENZYME E2-24 KDA Authors: Glover, M, Williams, R.S. Deposit date: 2000-10-04 Release date: 2001-10-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail. Structure, 9, 2001
4QPL	Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex Descriptor: 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate), E3 ubiquitin-protein ligase RNF146, Ubiquitin-conjugating enzyme E2 D1, ... Authors: Wang, Z, DaRosa, P.A, Klevit, R.E, Xu, W. Deposit date: 2014-06-23 Release date: 2014-10-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal. Nature, 517, 2015
1J74	Crystal Structure of Mms2 Descriptor: MMS2 Authors: Moraes, T.F, Edwards, R.A, McKenna, S, Pastushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J. Deposit date: 2001-05-15 Release date: 2001-08-08 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13. Nat.Struct.Biol., 8, 2001
4LDT	The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ... Authors: Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C. Deposit date: 2013-06-25 Release date: 2013-08-14 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.901 Å) Cite: E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1. Nat.Struct.Mol.Biol., 20, 2013
5D0M	Structure of UbE2D2:RNF165:Ub complex Descriptor: PHOSPHATE ION, Polyubiquitin-B, RING finger protein 165, ... Authors: Wright, J.D, Day, C.L, Mace, P.D. Deposit date: 2015-08-03 Release date: 2015-12-09 Last modified: 2016-01-20 Method: X-RAY DIFFRACTION (1.913 Å) Cite: Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity. Nat.Struct.Mol.Biol., 23, 2016
1ZDN	Ubiquitin-conjugating enzyme E2S Descriptor: SODIUM ION, Ubiquitin-conjugating enzyme E2S Authors: Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2005-04-14 Release date: 2005-05-03 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.93 Å) Cite: A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics, 11, 2012
2CLW	Crystal structure of human ubiquitin-conjugating enzyme UbcH5B Descriptor: GLYCEROL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E2 D2 Authors: Dodd, R.B, Read, R.J. Deposit date: 2006-05-02 Release date: 2007-06-12 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.945 Å) Cite: Structures of Two Human Ubiquitin-Conjugating Enzymes from Twinned Crystals To be Published
4NRG	Crystal Structure of a human Mms2/Ubc13 D118G mutant Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 Authors: Hodge, C.D, Edwards, R.A, Glover, J.N.M. Deposit date: 2013-11-26 Release date: 2014-12-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes. J.Am.Chem.Soc., 136, 2014
5ULH	Structure of RNF165 in complex with a UbcH5b~Ub conjugate Descriptor: E3 ubiquitin-protein ligase RNF165, GLYCEROL, THIOCYANATE ION, ... Authors: Middleton, A.J, Day, C.L, Wright, J.D. Deposit date: 2017-01-24 Release date: 2017-06-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Discovery of new non-covalent ubiquitin binding sites on UbcH5 To be published
1I7K	CRYSTAL STRUCTURE OF HUMAN MITOTIC-SPECIFIC UBIQUITIN-CONJUGATING ENZYME, UBCH10 Descriptor: UBIQUITIN-CONJUGATING ENZYME E2 H10 Authors: Basavappa, R, Lin, Y. Deposit date: 2001-03-09 Release date: 2001-04-04 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10. J.Biol.Chem., 277, 2002
6QHK	PAO-linked dimer of the catalytic domain of the human ubiquitin-conjugating enzyme UBE2S Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Phenylarsine oxide, ... Authors: Liess, A.K.L, Lorenz, S. Deposit date: 2019-01-16 Release date: 2019-07-17 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination. Structure, 27, 2019
6ULH	Structure of MavC in complex with its substrate in R3 spacegroup Descriptor: LPG2147 (MavC), Ubiquitin, Ubiquitin-conjugating enzyme E2 N Authors: Iyer, S, Puvar, K, Das, C. Deposit date: 2019-10-08 Release date: 2020-05-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.968 Å) Cite: Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
8E2E	Cryo-EM structure of helical arch of BIRC6 (from local refinement 1) Descriptor: Baculoviral IAP repeat-containing protein 6 Authors: Hunkeler, M, Fischer, E.S. Deposit date: 2022-08-15 Release date: 2023-02-15 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (1.98 Å) Cite: Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases. Science, 379, 2023
4Q5H	Shigella Effector Kinase OspG bound to AMPPNP and E2-Ub UbcH7-Ub Conjugate Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Polyubiquitin, ... Authors: Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2014-04-16 Release date: 2014-07-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.999 Å) Cite: Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure, 22, 2014

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