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4R8I
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High Resolution Structure of a Mirror-Image RNA Oligonucleotide Aptamer in Complex with the Chemokine CCL2
Descriptor: C-C motif chemokine 2, Mirror-Image RNA Oligonucleotide Aptamer NOXE36, POTASSIUM ION, ...
Authors:Oberthuer, D, Achenbach, J, Gabdulkhakov, A, Falke, S, Buchner, K, Maasch, C, Rehders, D, Klussmann, S, Betzel, C.
Deposit date:2014-09-02
Release date:2015-04-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.
Nat Commun, 6, 2015
4RAU
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crystal structure of RTOFab in complex with human PF4
Descriptor: Platelet factor 4, RTOFab heavy chain, RTOFab light chain
Authors:Cai, Z, Zhu, Z, Liu, Q, Greene, M.I.
Deposit date:2014-09-11
Release date:2016-03-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.74 Å)
Cite:crystal structure of RTOFab in complex with platelet factor 4
To be Published
4R9Y
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Crystal structure of KKOFab in complex with platelet factor 4
Descriptor: Platelet factor 4, Platelet factor 4 antibody KKO heavy chain, Platelet factor 4 antibody KKO light chain
Authors:Cai, Z, Zhu, Z, Liu, Q, Greene, M.I.
Deposit date:2014-09-08
Release date:2015-12-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.11 Å)
Cite:Atomic description of the immune complex involved in heparin-induced thrombocytopenia.
Nat Commun, 6, 2015
1SDF
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BU of 1sdf by Molmil
SOLUTION STRUCTURE OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: STROMAL CELL-DERIVED FACTOR-1
Authors:Crump, M.P, Rajarathnam, K, Clark-Lewis, I, Sykes, B.D.
Deposit date:1997-11-15
Release date:1998-01-28
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.
EMBO J., 16, 1997
1U4L
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human RANTES complexed to heparin-derived disaccharide I-S
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACETIC ACID, Small inducible cytokine A5
Authors:Shaw, J.P, Johnson, Z, Borlat, F, Zwahlen, C, Kungl, A, Roulin, K, Harrenga, A, Wells, T.N.C, Proudfoot, A.E.I.
Deposit date:2004-07-26
Release date:2004-11-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.
Structure, 12, 2004
1U4M
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human RANTES complexed to heparin-derived disaccharide III-S
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose, ACETIC ACID, Small inducible cytokine A5
Authors:Shaw, J.P, Johnson, Z, Borlat, F, Zwahlen, C, Kungl, A, Roulin, K, Harrenga, A, Wells, T.N.C, Proudfoot, A.E.I.
Deposit date:2004-07-26
Release date:2004-11-09
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.
Structure, 12, 2004
1U4P
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Crystal Structure of human RANTES mutant K45E
Descriptor: ACETIC ACID, Small inducible cytokine A5
Authors:Shaw, J.P, Johnson, Z, Borlat, F, Zwahlen, C, Kungl, A, Roulin, K, Harrenga, A, Wells, T.N.C, Proudfoot, A.E.I.
Deposit date:2004-07-26
Release date:2004-11-09
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.
Structure, 12, 2004
1TVX
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NEUTROPHIL ACTIVATING PEPTIDE-2 VARIANT FORM M6L WITH FIVE ADDITIONAL AMINO TERMINAL RESIDUES (DSDLY)
Descriptor: NEUTROPHIL ACTIVATING PEPTIDE 2 VARIANT
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1996-11-05
Release date:1997-01-11
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The amino-terminal residues in the crystal structure of connective tissue activating peptide-III (des10) block the ELR chemotactic sequence.
J.Mol.Biol., 266, 1997
1VMP
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STRUCTURE OF THE ANTI-HIV CHEMOKINE VMIP-II
Descriptor: PROTEIN (ANTI-HIV CHEMOKINE MIP VII)
Authors:Liwang, A.C, Wang, Z.-X, Sun, Y, Peiper, S.C, Liwang, P.J.
Deposit date:1999-03-25
Release date:1999-11-24
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The solution structure of the anti-HIV chemokine vMIP-II.
Protein Sci., 8, 1999
1VMC
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STROMA CELL-DERIVED FACTOR-1ALPHA (SDF-1ALPHA)
Descriptor: Stromal cell-derived factor 1
Authors:Gozansky, E.K, Clore, G.M.
Deposit date:2004-09-20
Release date:2005-03-01
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha.
J.Mol.Biol., 345, 2005
1U4R
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BU of 1u4r by Molmil
Crystal Structure of human RANTES mutant 44-AANA-47
Descriptor: SULFATE ION, Small inducible cytokine A5
Authors:Shaw, J.P, Johnson, Z, Borlat, F, Zwahlen, C, Kungl, A, Roulin, K, Harrenga, A, Wells, T.N.C, Proudfoot, A.E.I.
Deposit date:2004-07-26
Release date:2004-11-09
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.
Structure, 12, 2004
1IKL
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NMR study of monomeric human interleukin-8 (minimized average structure)
Descriptor: HUMAN INTERLEUKIN-8 (MONOMERIC)
Authors:Rajarathnam, K, Clark-Lewis, I, Sykes, B.D.
Deposit date:1995-08-03
Release date:1995-10-15
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:1H NMR solution structure of an active monomeric interleukin-8.
Biochemistry, 34, 1995
1IL8
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THREE-DIMENSIONAL STRUCTURE OF INTERLEUKIN 8 IN SOLUTION
Descriptor: INTERLEUKIN-8
Authors:Clore, G.M, Gronenborn, A.M.
Deposit date:1990-03-08
Release date:1991-01-15
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Three-dimensional structure of interleukin 8 in solution.
Biochemistry, 29, 1990
1J9O
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SOLUTION STRUCTURE OF HUMAN LYMPHOTACTIN
Descriptor: LYMPHOTACTIN
Authors:Kuloglu, E.S, McCaslin, D.R, Kitabwalla, M, Pauza, C.D, Markley, J.L, Volkman, B.F.
Deposit date:2001-05-28
Release date:2001-10-24
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Monomeric solution structure of the prototypical 'C' chemokine lymphotactin.
Biochemistry, 40, 2001
1JE4
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BU of 1je4 by Molmil
Solution structure of the monomeric variant of the chemokine MIP-1beta
Descriptor: macrophage inflammatory protein 1-beta
Authors:Kim, S, Jao, S, Laurence, J.S, LiWang, P.J.
Deposit date:2001-06-15
Release date:2001-10-03
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Structural comparison of monomeric variants of the chemokine MIP-1beta having differing ability to bind the receptor CCR5.
Biochemistry, 40, 2001
4ZLT
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BU of 4zlt by Molmil
Crystal structure of viral chemokine binding protein R17 in complex with CCL3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 3, Putative uncharacterized protein
Authors:Lubman, O.Y, Fremont, D.H.
Deposit date:2015-05-01
Release date:2015-11-18
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors.
Structure, 24, 2016
5COY
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BU of 5coy by Molmil
Crystal structure of CC chemokine 5 (CCL5)
Descriptor: C-C motif chemokine 5, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
Authors:Liang, W.G, Tang, W.
Deposit date:2015-07-20
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.443 Å)
Cite:Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
1LV9
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BU of 1lv9 by Molmil
CXCR3 Binding Chemokine IP-10/CXCL10
Descriptor: Small inducible cytokine B10
Authors:Booth, V, Keizer, D.W, Kamphuis, M.B, Clark-Lewis, I, Sykes, B.D.
Deposit date:2002-05-27
Release date:2002-09-18
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions.
Biochemistry, 41, 2002
1MI2
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BU of 1mi2 by Molmil
SOLUTION STRUCTURE OF MURINE MACROPHAGE INFLAMMATORY PROTEIN-2, NMR, 20 STRUCTURES
Descriptor: MACROPHAGE INFLAMMATORY PROTEIN-2
Authors:Shao, W, Jerva, L.F, West, J, Lolis, E, Schweitzer, B.I.
Deposit date:1997-10-24
Release date:1998-04-29
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Solution structure of murine macrophage inflammatory protein-2.
Biochemistry, 37, 1998
5CMD
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BU of 5cmd by Molmil
Oligomer crystal structure of CC chemokine 5 (CCL5)
Descriptor: C-C motif chemokine 5, SULFATE ION
Authors:Liang, W.G, Tang, W.-J.
Deposit date:2015-07-16
Release date:2016-04-13
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.086 Å)
Cite:Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
5COR
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BU of 5cor by Molmil
X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) N-TERMINAL-SWITCH POLYMER
Descriptor: ACETATE ION, C-C motif chemokine 3, HEXANE-1,6-DIOL
Authors:Liang, W.G, Tang, W.
Deposit date:2015-07-20
Release date:2016-04-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.548 Å)
Cite:Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
1M8A
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BU of 1m8a by Molmil
Human MIP-3alpha/CCL20
Descriptor: ISOPROPYL ALCOHOL, Small inducible cytokine A20
Authors:Hoover, D.M, Boulegue, C, Yang, D, Oppenheim, J.J, Tucker, K, Lu, W, Lubkowski, J.
Deposit date:2002-07-24
Release date:2002-07-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins
J.Biol.Chem., 277, 2002
1MGS
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BU of 1mgs by Molmil
THE SOLUTION STRUCTURE OF MELANOMA GROWTH STIMULATING ACTIVITY
Descriptor: HUMAN MELANOMA GROWTH STIMULATORY ACTIVITY
Authors:Fairbrother, W.J.
Deposit date:1994-07-19
Release date:1994-09-30
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The solution structure of melanoma growth stimulating activity.
J.Mol.Biol., 242, 1994
1MSG
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SOLUTION STRUCTURE OF GRO(SLASH)MELANOMA GROWTH STIMULATORY ACTIVITY DETERMINED BY 1H NMR SPECTROSCOPY
Descriptor: HUMAN MELANOMA GROWTH STIMULATORY ACTIVITY
Authors:Kim, K.-S, Clark-Lewis, I, Sykes, B.D.
Deposit date:1995-01-25
Release date:1995-03-31
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Solution structure of GRO/melanoma growth stimulatory activity determined by 1H NMR spectroscopy.
J.Biol.Chem., 269, 1994
5D65
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X-RAY STRUCTURE OF MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (CCL3) WITH HEPARIN COMPLEX
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-C motif chemokine 3, CHLORIDE ION, ...
Authors:Liang, W.G, Hwang, D.Y, Zulueta, M.M, Hung, S.C, Tang, W.
Deposit date:2015-08-11
Release date:2016-04-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016

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