2NGR
| TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP. | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nassar, N, Hoffman, G, Clardy, J, Cerione, R. | Deposit date: | 1998-07-31 | Release date: | 1999-01-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP. Nat.Struct.Biol., 5, 1998
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1RRP
| STRUCTURE OF THE RAN-GPPNHP-RANBD1 COMPLEX | Descriptor: | MAGNESIUM ION, NUCLEAR PORE COMPLEX PROTEIN NUP358, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Vetter, I.R, Nowak, C, Nishimoto, T, Kuhlmann, J, Wittinghofer, A. | Deposit date: | 1999-01-15 | Release date: | 1999-05-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport. Nature, 398, 1999
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2NTY
| Rop4-GDP-PRONE8 | Descriptor: | Emb|CAB41934.1, GUANOSINE-5'-DIPHOSPHATE, Rac-like GTP-binding protein ARAC5 | Authors: | Thomas, C, Fricke, I, Scrima, A, Berken, A, Wittinghofer, A. | Deposit date: | 2006-11-08 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Evidence for a Common Intermediate in Small G Protein-GEF Reactions Mol.Cell, 25, 2007
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2MSD
| NMR data-driven model of GTPase KRas-GNP tethered to a lipid-bilayer nanodisc | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | Authors: | Mazhab-Jafari, M, Stathopoulos, P, Marshall, C, Ikura, M. | Deposit date: | 2014-07-29 | Release date: | 2015-06-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site. Proc.Natl.Acad.Sci.USA, 112, 2015
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2NZ8
| N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1 | Descriptor: | ras-related C3 botulinum toxin substrate 1 isoform Rac1, triple functional domain protein | Authors: | Chhatriwala, M.K, Betts, L, Worthylake, D.K, Sondek, J. | Deposit date: | 2006-11-22 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation J.Mol.Biol., 368, 2007
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2KWI
| RalB-RLIP76 (RalBP1) complex | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RalA-binding protein 1, ... | Authors: | Fenwick, R.B, Campbell, L.J, Rajasekar, K, Prasannan, S, Nietlispach, D, Camonis, J, Owen, D, Mott, H.R. | Deposit date: | 2010-04-12 | Release date: | 2010-09-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction Structure, 18, 2010
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4LWZ
| Crystal structure of Myo5b globular tail domain in complex with inactive Rab11a | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-11A, ... | Authors: | Pylypenko, O, Attanda, W, Gauquelin, C, Houdusse, A. | Deposit date: | 2013-07-29 | Release date: | 2013-11-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis of myosin V Rab GTPase-dependent cargo recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
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4M8N
| Crystal Structure of PlexinC1/Rap1B Complex | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Pascoe, H.G, Wang, Y, Brautigam, C.A, He, H, Zhang, X. | Deposit date: | 2013-08-13 | Release date: | 2013-10-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.294 Å) | Cite: | Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin. Elife, 2, 2013
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4MIT
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3BC1
| Crystal Structure of the complex Rab27a-Slp2a | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-27A, ... | Authors: | Chavas, L.M.G, Ihara, K, Kawasaki, M, Wakatsuki, S. | Deposit date: | 2007-11-12 | Release date: | 2008-09-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a Structure, 16, 2008
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4NYI
| Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange | Descriptor: | GTPase HRas, MAGNESIUM ION, N-{1-[(5-methyl-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide, ... | Authors: | Burns, M.C, Sun, Q, Phan, J, Fesik, S.W. | Deposit date: | 2013-12-10 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9612 Å) | Cite: | Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange. Proc.Natl.Acad.Sci.USA, 111, 2014
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4OL0
| Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex with Ran | Descriptor: | GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Tsirkone, V.G, Strelkov, S.V. | Deposit date: | 2014-01-23 | Release date: | 2014-04-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran. Acta Crystallogr.,Sect.F, 70, 2014
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3CH5
| The crystal structure of the RanGDP-Nup153ZnF2 complex | Descriptor: | Fragment of Nuclear pore complex protein Nup153, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Vetter, I.R, Schrader, N. | Deposit date: | 2008-03-07 | Release date: | 2008-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of the Ran-Nup153ZnF2 Complex: a General Ran Docking Site at the Nuclear Pore Complex Structure, 16, 2008
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3BJI
| Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1 | Descriptor: | Proto-oncogene vav, Ras-related C3 botulinum toxin substrate 1 precursor, ZINC ION | Authors: | Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | Deposit date: | 2007-12-04 | Release date: | 2008-07-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. J.Mol.Biol., 380, 2008
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3CPJ
| Crystal structure of Ypt31 in complex with yeast Rab-GDI | Descriptor: | CHLORIDE ION, GTP-binding protein YPT31/YPT8, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. | Deposit date: | 2008-03-31 | Release date: | 2008-05-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008
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3CUE
| Crystal structure of a TRAPP subassembly activating the Rab Ypt1p | Descriptor: | GTP-binding protein YPT1, PALMITIC ACID, Transport protein particle 18 kDa subunit, ... | Authors: | Cai, Y, Reinisch, K.M. | Deposit date: | 2008-04-16 | Release date: | 2008-07-08 | Last modified: | 2012-03-21 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes. Cell(Cambridge,Mass.), 133, 2008
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3CWZ
| Structure of RAB6(GTP)-R6IP1 complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab6-interacting protein 1, ... | Authors: | Recacha, R, Houdusse, A, Goud, B, Khan, A.R. | Deposit date: | 2008-04-23 | Release date: | 2008-11-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain. Structure, 17, 2009
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3BBP
| Rab6-GTP:GCC185 Rab binding domain complex | Descriptor: | GRIP and coiled-coil domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Schweizer Burguete, A, Fenn, T.D, Brunger, A.T, Pfeffer, S.R. | Deposit date: | 2007-11-09 | Release date: | 2008-02-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. Cell(Cambridge,Mass.), 132, 2008
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3CPH
| Crystal structure of Sec4 in complex with Rab-GDI | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rab GDP-dissociation inhibitor, ... | Authors: | Kravchenko, S, Ignatev, A, Goody, R.S, Rak, A, Pylypenko, O. | Deposit date: | 2008-03-31 | Release date: | 2008-05-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism. J.Biol.Chem., 283, 2008
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3DDC
| Crystal Structure of NORE1A in Complex with RAS | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Stieglitz, B, Bee, C, Schwarz, D, Yildiz, O, Moshnikova, A, Khokhlatchev, A, Herrmann, C. | Deposit date: | 2008-06-05 | Release date: | 2008-07-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II Embo J., 27, 2008
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4NYM
| Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange | Descriptor: | GTPase HRas, MAGNESIUM ION, N-[1-(1H-indol-3-ylmethyl)piperidin-4-yl]-L-tryptophanamide, ... | Authors: | Burns, M.C, Sun, Q, Phan, J, Fesik, S.W. | Deposit date: | 2013-12-10 | Release date: | 2014-03-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5529 Å) | Cite: | Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange. Proc.Natl.Acad.Sci.USA, 111, 2014
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3B13
| Crystal structure of the DHR-2 domain of DOCK2 in complex with Rac1 (T17N mutant) | Descriptor: | Dedicator of cytokinesis protein 2, Ras-related C3 botulinum toxin substrate 1 | Authors: | Hanawa-Suetsugu, K, Kukimoto-Niino, M, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S. | Deposit date: | 2011-06-24 | Release date: | 2012-03-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.006 Å) | Cite: | Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms. Proc.Natl.Acad.Sci.USA, 109, 2012
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3CLV
| Crystal Structure of Rab5a from plasmodium falciparum, PFB0500c | Descriptor: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Rab5 protein, ... | Authors: | Chattopadhyay, D, Wernimont, A.K, Langsley, G, Lew, J, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Sukumar, D, Structural Genomics Consortium (SGC) | Deposit date: | 2008-03-20 | Release date: | 2008-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Crystal Structure of Rab5a from plasmodium falciparum, PFB0500c To be Published
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3BRW
| Structure of the Rap-RapGAP complex | Descriptor: | BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Scrima, A, Thomas, C, Deaconescu, D, Wittinghofer, A. | Deposit date: | 2007-12-21 | Release date: | 2008-03-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues Embo J., 27, 2008
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3EA5
| Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics | Descriptor: | GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ... | Authors: | Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B. | Deposit date: | 2008-08-24 | Release date: | 2008-10-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. J.Mol.Biol., 383, 2008
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